Prognostic factors in children with extragonadal malignant germ cell tumors: A pediatric intergroup study

Journal of Clinical Oncology

Volumn 24, Issue 16, 2006, Pages 2544-2548

  Marina, Neyssa ^a   London, Wendy B ^a   Frazier, A Lindsay ^a   Lauer, Stephen ^a   Rescorla, Frederick ^a   Cushing, Barbara ^a   Malogolowkin, Marcio H ^a   Castleberry, Robert P ^a   Womer, Richard B ^a   Olson, Thomas ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; BLEOMYCIN; CISPLATIN; ETOPOSIDE; TUMOR MARKER;

ARTICLE; CANCER LOCALIZATION; CANCER STAGING; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DRUG DOSE REGIMEN; DRUG MEGADOSE; FEMALE; GERM CELL TUMOR; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; NEWBORN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL TIME; ADOLESCENT; AGE; ANALYSIS OF VARIANCE; BLOOD; CHILD; METABOLISM; PATHOLOGY; PREDICTION AND FORECASTING; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; SURVIVAL;

ADOLESCENT; AGE FACTORS; ALPHA-FETOPROTEINS; ANALYSIS OF VARIANCE; CHILD; DISEASE-FREE SURVIVAL; FEMALE; GERMINOMA; HUMANS; MALE; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 33744969142     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.04.1251     Document Type: Article

References (29)

1. Bernstein L, Smith MA, Liu L, et al: Germ Cell, Trophoblastic and Other Gonadal Neoplasms, in Ries LAG SM, Gurney JG, Linet M, Tamra T, Young JL, Bunin GR (eds): Cancer Incidence and Survival among Children and Adolescents: United States SEER Program 1975-1995, National Cancer Institute, SEER Program. Bethesda, Cancer Statistics Branch Cancer Surveillance Research Program Division of Cancer Control and Population Sciences National Cancer Institute, Bethesda, MD, 1999, pp 125-138
2. Miller RW, Young JL Jr, Novakovic B: Childhood cancer. Cancer 75:395-405, 1995
3. Mulligan RM: Pathogenesis of teratoid tumors of the ovary and testis. Pathol Annu 10:271-298, 1975
4. Dehner LP: Gonadal and extragonadal germ cell neoplasia of childhood. Hum Pathol 14:493-511, 1983
5. Marina N, Fontanesi J, Kun L, et al: Treatment of childhood germ cell tumors. Review of the St. Jude experience from 1979 to 1988. Cancer 70:2568-2575, 1992
6. Mann JR, Pearson D, Barrett A, et al: Results of the United Kingdom Children's Cancer Study Group's malignant germ cell tumor studies. Cancer 63:1657-1667, 1989
7. Chretien PB, Milam JD, Foote FW, et al: Embryonal adenocarcinomas (a type of malignant teratoma) of the sacrococcygeal region: Clinical and pathologic aspects of 21 cases. Cancer 26:522-535, 1970
8. Kurman RJ, Norris HJ: Endodermal sinus tumor of the ovary: A clinical and pathologic analysis of 71 cases. Cancer 38:2404-2419, 1976
9. Slayton RE, Hreshchyshyn MM, Silverberg SC, et al: Treatment of malignant ovarian germ cell tumors: Response to vincristine, dactinomycin, and cyclophosphamide (preliminary report). Cancer 42:390-398, 1978
10. Slayton RE, Park RC, Silverberg SG, et al: Vincristine, dactinomycin, and cyclophosphamide in the treatment of malignant germ cell tumors of the ovary. A Gynecologic Oncology Group Study (a final report). Cancer 56:243-248, 1985
11. Cangir A, Smith J, van Eys J: Improved prognosis in children with ovarian cancers following modified VAC (vincristine sulfate, dactinomycin, and cyclophosphamide) chemotherapy. Cancer 42:1234-1238, 1978
12. Brodeur GM, Howarth CB, Pratt CB, et al: Malignant germ cell tumors in 57 children and adolescents. Cancer 48:1890-1898, 1981
13. Einhorn LH, Donohue J: Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer. Ann Intern Med 87:293-298, 1977
14. Mann JR, Raafat F, Robinson K, et al: The United Kingdom Children's Cancer Study Group's second germ cell tumor study: Carboplatin, etoposide, and bleomycin are effective treatment for children with malignant extracranial germ cell tumors, with acceptable toxicity. J Clin Oncol 18:3809-3818, 2000
15. Gobel U, Schneider DT, Calaminus G, et al: Germ-cell tumors in childhood and adolescence. GPOH MAKEI and the MAHO study groups. Ann Oncol 11:263-271, 2000
16. Cushing B, Giller R, Cullen JW, et al: Randomized Comparison of Combination Chemotherapy With Etoposide, Bleomycin, and Either High-Dose or Standard-Dose Cisplatin in Children and Adolescents With High-Risk Malignant Germ Cell Tumors: A Pediatric Intergroup Study - Pediatric Oncology Group 9049 and Children's Cancer Group 8882. J Clin Oncol 22:2691-2700, 2004
17. International Germ Cell Consensus Classification: A prognostic factor- based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group. J Clin Oncol 15:594-603, 1997
18. Baranzelli MC, Kramar A, Bouffet E, et al: Prognostic factors in children with localized malignant nonseminomatous germ cell tumors. J Clin Oncol 17:1212, 1999
19. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
20. Peto R, Peto J: Assymptotically efficient rank invariant test procedures. J R Stat Soc A 135:185-198, 1972
21. Cox DR: Regression Models and Life Tables (with discussion). J R Stat Soc B 34:187-220, 1972
22. Altman DG, Lausen B, Sauerbrei W, et al: Dangers of using "optimal" outpoints in the evaluation of prognostic factors. J Natl Cancer Inst 86:829-835, 1994
23. Nichols CR, Williams SD, Loehrer PJ, et al: Randomized study of cisplatin dose intensity in poor-risk germ cell tumors: A Southeastern Cancer Study Group and Southwest Oncology Group protocol. J Clin Oncol 9:1163-1172, 1991
24. Cushing B, Giller R, Lauer S, et al: Comparison of high dose or standard dose cisplatin with etoposide and bleomycin (HDPEB vs PEB) in children with stage I-IV extragonadal malignant germ cell tumors (MGCT): A Pediatric Intergroup report (POG9049/CCG8882), in Perry MC (ed): American Society of Clinical Oncology. Los Angeles, CA, W.B. Saunders Co, 1998, p 525
25. Horwich A, Sleijfer D, Fossa S, et al: Randomized trail of bleomycin, etoposide, and cisplatin compared with bleomycin, etoposide and carboplatin in good-prognosis metastatic nonseminomatous germ cell cancer: A multi-institutional medical research council/European organization for research and treatment of cancer trial. J Clin Oncol 15:1844-1852, 1997
26. Hartmann JT, Nichols CR, Droz JP, et al: Hematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors. J Natl Cancer Inst 92:54-61, 2000
27. Rogers PC, Olson TA, Cullen JW, et al: Treatment of children and adolescents with stage II testicular and stages I and II ovarian malignant germ cell tumors: A Pediatric Intergroup Study - Pediatric Oncology Group 9048 and Children's Cancer Group 8891. J Clin Oncol 22:3563-3569, 2004
28. Schneider DT, Schuster AE, Fritsch MK, et al: Genetic analysis of mediastinal nonseminomatous germ cell tumors in children and adolescents. Genes Chromosomes Cancer 34:115-125, 2002
29. Marina N, Chang KW, Malogolowkin M, et al: Amifostine does not protect against the ototoxicity of high-dose cisplatin combined with etoposide and bleomycin in pediatric germ-cell tumors. Cancer 104:841-847, 2005