Enantiomeric separation of mineralocorticoid receptor (hMR) antagonists using the Chiralcel® OJ-H HPLC column with novel polar cosolvent eluent systems

Chirality

Volumn 18, Issue 6, 2006, Pages 437-445

  Sharp, V Scott ^a   Kennedy, Joseph H ^a   Belvo, Matthew D ^a   Williams, Jeffrey D ^a   Risley, Donald S ^a   Seest, Eric P ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Chiral separation; Chirality; Enantioseparation; Polar organic mode; Resolution

Indexed keywords

ACETONITRILE; ALCOHOL; INDOLE DERIVATIVE; METHANOL; MINERALOCORTICOID ANTAGONIST; MINERALOCORTICOID RECEPTOR; SOLVENT;

ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERISM; MOLECULAR WEIGHT; PRIORITY JOURNAL; STEREOCHEMISTRY; STEREOSPECIFICITY; THREE DIMENSIONAL IMAGING;

ACETONITRILES; ALCOHOLS; CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PHARMACEUTICAL PREPARATIONS; RECEPTORS, MINERALOCORTICOID; SENSITIVITY AND SPECIFICITY; SOLVENTS; STEREOISOMERISM;

EID: 33744951286     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20269     Document Type: Article

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