DTX5c, a new OA sulphate ester derivative from cultures of Prorocentrum belizeanum

Toxicon

Volumn 47, Issue 8, 2006, Pages 920-924

  Cruz, Patricia G ^a   Daranas, Antonio H ^a   Fernández, José J ^a   Souto, María L ^a   Norte, Manuel ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

Dinophysistoxins; DSP; DTX5c; Marine toxins; Okadaic acid

Indexed keywords

DINOPHYSISTOXIN 5C; MARINE TOXIN; OKADAIC ACID; SULFATE; UNCLASSIFIED DRUG; WATER;

ALGA; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DINOFLAGELLATE; ISOLATION PROCEDURE; NONHUMAN; PRIORITY JOURNAL; PROROCENTRUM BELIZEANUM; SOLUBILITY; SPECTROSCOPY; TOXIN ANALYSIS; TOXIN STRUCTURE;

ANIMALS; DINOFLAGELLIDA; MOLECULAR STRUCTURE; OKADAIC ACID;

DINOPHYCEAE; PROROCENTRUM BELIZEANUM;

EID: 33744946273     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.03.005     Document Type: Article

References (12)

1. Britton R., Roberge M., Brown C., Van Soest R., and Andersen R.J. New okadaic acid analogues from the marine sponge Meriamum oxeato and their effects on mitosis. J. Nat. Prod. 66 6 (2003) 838-843
2. Daranas A.H., Norte M., and Fernández J.J. Toxic marine microalgae. Toxicon 39 8 (2001) 1101-1132
3. Fernández J.J., Candenas M.L., Souto M.L., Trujillo M.M., and Norte M. Okadaic acid, useful tool for studying cellular processes. Curr. Med. Chem. 9 2 (2002) 229-262
4. Fernández J.J., Suárez-Gómez B., Souto M.L., and Norte M. Identification a new okadaic acid derivative from laboratory cultures of Prorocentrum lima. J. Nat. Prod. 66 9 (2003) 1294-1296
5. Hu T., de Freitas A.S.W., Marr J., Quilliam M.A., Walter J.A., and Wright J.L.C. New diol esters (of okadaic acid) isolated from cultures of the dinoflagellates Prorocentrum lima and Prorocentrum concavum. J. Nat. Prod. 55 11 (1992) 1631-1637
6. Hu T., Curtis J.M., Walter J.A., McLachlan J.L., and Wright J.L.C. Two new water-soluble DSP toxin derivatives from the dinoflagellate Prorocentrum maculosum: possible storage and excretion products. Tetrahedron Lett. 36 51 (1995) 9273-9276
7. Hu T., Curtis J.M., Walter J.A., and Wright J.L.C. J. Chem. Soc., Chem. Commun. (1995) 597-599
8. Morton S.L., Moeller P.D.R., Young K.A., and Lanoue B. Okadaic acid production from the marine dinoglagellate Prorocentrum beliceanum faust isolated from the Belizean coral reef ecosystem. Toxicon 36 1 (1998) 201-206
9. Norte M., Padilla A., Fernández J.J., and Souto M.L. Structural determination and biosynthetic origin of two ester derivatives of okadaic acid isolated from Prorocentrum lima. Tetrahedron 50 30 (1994) 9175-9180
10. Suárez-Gómez B., Souto M.L., Norte M., and Fernández J.J. Isolation and structural determination of DTX6, a new okadaic acid derivative. J. Nat. Prod. 64 10 (2001) 1363-1364
11. Suárez-Gómez B., Souto M.L., Cruz P.G., Fernández J.J., and Norte M. New targets in diarrhetic shellfish poisoning control. J. Nat. Prod. 68 4 (2005) 596-599
12. Yasumoto T., and Murata M. Marine toxins. Chem. Rev. 93 5 (1993) 1867-1909