Class 1 integrons in resistant Escherichia coli and Klebsiella spp., US hospitals

Emerging Infectious Diseases

Volumn 12, Issue 6, 2006, Pages 1011-1014

  Rao, Aarati N ^a,c   Barlow, Miriam ^a,d   Clark, Leigh Ann ^b   Boring III, John R ^a   Tenover, Fred C ^b   McGowan Jr , John E ^a,e  

^a EMORY UNIVERSITY   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c MIDWESTERN UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIINFECTIVE AGENT; AZTREONAM; BETA LACTAMASE INHIBITOR; CARBAPENEM DERIVATIVE; CEFEPIME; CEFOTAXIME; CEFPODOXIME; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CHLORAMPHENICOL; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; MINOCYCLINE; MONOBACTAM; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; QUINOLONE DERIVATIVE; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL INFECTION; BACTERIUM ISOLATION; DISEASE CONTROL; DRUG SENSITIVITY; ESCHERICHIA COLI; GEL ELECTROPHORESIS; HOSPITAL INFECTION; HUMAN; INTEGRON; KLEBSIELLA; NONHUMAN; POLYMERASE CHAIN REACTION; PREVALENCE; RISK FACTOR; UNITED STATES;

EID: 33744937618     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid1206.051596     Document Type: Article

References (15)

1. Leverstein-van Hall MA, Blok HEM, Donders ART, Paauw A, Fluit AC, Verhoef J. Multidrug resistance among Enterobacteriaceae is strongly associated with the presence of integrons and is independent of species or isolate origin. J Infect Dis. 2003;187:251-9.
2. Norrby SR. Integrons: adding another threat to the use of antibiotic therapy. Clin Infect Dis. 2005;41:10-1.
3. Sallen B, Rajoharison A, Desvarenne S, Mabilat C. Molecular epidemiology of integron-associated antibiotic resistance genes in clinical isolates of Enterobacteriaceae. Microb Drug Resist. 1995;1:195-202.
4. Martinez-Freijo P, Fluit AC, Schmitz FJ, Grek VS, Verhoef J, Jones ME. Class I integrons in gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compounds. J Antimicrob Chemother. 1998;42:689-96.
5. Yu HS, Lee JC, Kang HY, Ro DW, Chung JY, Jeong YS, et al. Changes in gene cassettes of class 1 integrons among Escherichia coli isolates from urine specimens collected in Korea during the last two decades. J Clin Microbiol. 2003;41:5429-33.
6. McGowan JE Jr, Hill HA, Volkova NV, Lawton RM, Haber MJ, Tenover FC, et al. Does antimicrobial resistance cluster in individual hospitals? J Infect Dis. 2002;186:1362-5.
7. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. 6th ed. NCCLS document M7-A6. Wayne (PA): The Committee; 2003.
8. Forbes B, Sahm D, Weissfeld A. Enterobacteriaceae. Saint Louis (MO): Mosby; 1998.
9. Farmer JJ III. Enterobacteriaceae: introduction and identification. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, editors. Manual of clinical microbiology. 8th ed. Washington: American Society for Microbiology; 2003. p. 636-53.
10. Grape M, Farra A, Kronvall G, Sundstrom L. Integrons and gene cassettes in clinical isolates of co-trimoxazole-resistant gram-negative bacteria. Clin Microbiol Infect. 2005;11:185-92.
11. Heir E, Lindstedt BA, Leegaard TM, Gjernes E, Kapperud G. Prevalence and characterization of integrons in blood culture Enterobacteriaceae and gastrointestinal Escherichia coli in Norway and reporting of a novel class 1 integron-located lincosamide resistance gene. Ann Clin Microbiol Antimicrob. 2004;3:12.
12. Jones LA, McIver CJ, Kim MJ, Rawlinson WD, White PA. The aadB gene cassette is associated with blaSHV genes in Klebsiella species producing extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 2005;49:794-7.
13. Bonnet R. Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. Antimicrob Agents Chemother. 2004;48:1-14.
14. Machado E, Canton R, Baquero F, Galan JC, Rollan A, Peixe L, et al. Integron content of extended-spectrum-beta-lactamase-producing Escherichia coli strains over 12 years in a single hospital in Madrid, Spain. Antimicrob Agents Chemother. 2005;49:1823-9.
15. Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, et al. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med. 2006;12:83-8.