Effects of methotrexate on calcium flux in rat liver mitochondria, microsomes and plasma membrane vesicles

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 143, Issue 3, 2006, Pages 340-348

  Pagadigorria, Clairce L S ^a   Marcon, Fernanda ^a   Kelmer Bracht, Ana M ^a   Bracht, Adelar ^a   Ishii Iwamoto, Emy L ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Calcium transport; Liver; Methotrexate; Microsomes; Mitochondria; Plasma membrane

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; INOSITOL 1,4,5 TRISPHOSPHATE; METHOTREXATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; LIVER MITOCHONDRION; MALE; MEMBRANE VESICLE; MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 33744928425     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpc.2006.03.007     Document Type: Article

References (42)

1. Armstrong J.McD., and Newman J.D. A simple, rapid method for the preparation of plasma membranes from liver. Arch. Biochem. Biophys. 238 (1985) 619-628
2. 2+ channel antagonists and, in contrast to freshly isolated hepatocytes, does not require a pertussis toxin-sensitive trimeric GTP-binding protein. Biochem. Biophys. Acta 1497 (2000) 11-26
3. Barak A.J., Tuma D.J., and Beckenhauer H.C. Methotrexate hepatotoxicity. J. Am. Coll. Nutr. 3 (1985) 93-96
4. 2+ efflux from the intracellular stores of hepatocytes. Biochem. J. 334 (1998) 431-435
5. 2+ accumulation in liver microsomal fractions. Effects of inositol 1,4,5-triphosphate and GTP. J. Biol. Chem. 263 (1988) 3466-3473
6. Bergmeyer H.U., and Bernt E. Determination of glucose with glucose oxidase and peroxidase. In: Bergmeyer H.U. (Ed). Methods of Enzymatic Analysis (1974), Verlag Chemie/Academic Press, Weinheim/London 1205-1215
7. Berridge M.J. Capacitative calcium entry. Biochem. J. 312 (1995) 1-11
8. Betto R., Teresi A., Turcato F., Salviatti G., Sabbadini R.A., Krown K., Glembotski C.C., Kindman L.A., Dettbarn C., Pereon Y., Yasui K., and Palade P.T. Sphingosylphoscoline modulates the ryanodine receptor/calcium-release channel of cardiac sarcoplasmic reticulum membranes. Biochem. J. 322 (1997) 327-333
9. 2+ stores in induction and suppression of apoptosis in S49 cells. Am. J. Physiol. 272 (1997) C1241-C1249
10. Bootman M.D., Collins T.J., Peppiatt C.M., Prothero L.S., MacKenzie L., De Smet P., Travers M., Tovey S.C., Seo J.T., Berridge M.J., Ciccolini F., and Lipp P. Calcium signalling - an overview. Cell Dev. Biol. 12 (2001) 3-10
11. Bore O., Bruno R., Lena N., Favre R., and Cano J.P. Methotrexate and 7-hydroxy-methotrexate pharmacokinetics following intravenous bolus administration and high-dose infusion of methotrexate. Eur. J. Cancer Clin. Oncol. 23 (1987) 1385-1390
12. Burchell A., Hume R., and Burchell B. A new microtechnique for the analysis of the human hepatic microsomal glucose 6-phosphatase system. Clin. Chim. Acta 173 (1988) 183-192
13. Bygrave F.L. Properties of energy-dependent calcium transport by rat liver microsomal fraction as revealed by initial rate measurements. Biochem. J. 170 (1978) 87-91
14. Cronstein B.N., Eberle M.A., Gruber H.E., and Levin R.I. Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 2441-2445
15. 2+ fluxes in rat liver plasma-membrane vesicles. Biochem. J. 256 (1988) 117-124
16. 2+-stimulated ATPase of a rat liver microsomal fraction. Biochem. J. 210 (1983) 405-410
17. 2+ uptake and release properties of rat liver microsomes. Eur. J. Biochem. 234 (1995) 626-631
18. Fiske C.H., and Subbarow Y. The colorimetric determination of phosphorus. J. Biol. Chem. 66 (1925) 375-400
19. Genestier L., Paillot R., Fournel S., Ferraro C., Miossec P., and Revillard J.P. Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells. J. Clin. Invest. 102 (1998) 322-328
20. Genestier L., Paillot R., Quemeneur L., Izeradjene K., and Revillard J.P. Mechanisms of action of methotrexate. Immunopharmacology 47 (2000) 247-250
21. Hoth M., and Penner R. Calcium release-activated calcium current in rat mast cells. J. Physiol. 465 (1993) 359-386
22. Kobayashi K., Terada C., and Tsukamoto I. Methotrexate-induced apoptosis in hepatocytes after partial hepatectomy. Eur. J. Pharmacol. 438 (2002) 19-24
23. Lee H.C. A unified mechanism of enzymatic synthesis of two calcium messengers: cyclic ADP-ribose and NAADP. J. Biol. Chem. 380 (1999) 785-793
24. 2+-translocase inhibitors thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone on cellular calcium fluxes. Biochem. J. 277 (1991) 553-556
25. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with Folin phenol reagent. J. Biol. Chem. 193 (1982) 131-138
26. Merkle C.J., Moore I.M., Penton B.S., Torres B.J., Cueny R.K., Schaeffer Jr., and Montgomery D.W. Methotrexate causes apoptosis in postmitotic endothelial cells. Biol. Res. Nurs. 2 (2000) 5-14
27. Mihara K., and Sato R. Partial purification of NADH-cytochrome b5 reductase from rabbit liver microsomes with detergents and its properties. J. Biochem. 71 (1972) 725-735
28. Moore L., Chen T., Knapp Jr. H.R., and Landon E.J. Energy-dependent calcium sequestration activity in rat liver microsomes. J. Biol. Chem. 250 (1975) 4562-4568
29. 2+ by rat liver mitochondria. Chem. Pharm. Bull. 39 (1991) 224-226
30. Nishiyama A., Constantin J., Kelmer-Bracht A.M., Bracht A., and Ishii-Iwamoto E.L. Effects of methotrexate on ketogenesis in the perfused rat liver. Res. Commun. Pharmacol. Toxicol. 1 (1996) 51-65
31. Nishiyama A., Yamamoto N.S., Nascimento E.A., Kelmer-Bracht A.M., Bracht A., and Ishii-Iwamoto E.L. Effects of methotrexate on gluconeogenesis in the perfused rat liver. Res. Commun. Pharmacol. Toxicol. 1 (1996) 159-171
32. Oliveira M.B.M., Ishii E.L., Yamamoto N.S., Kelmer-Bracht A.M., Campelo A.P., Klüppel M.L.W., and Bracht A. Methotrexate increases glycogenolysis in the intact rat liver. Res. Commun. Chem. Pathol. Pharmacol. 53 (1986) 1273-1281
33. Parekh A.B., and Penner R. Store depletion and calcium influx. Physiol. Rev. 77 (1997) 901-930
34. Putney Jr. J.W. Capacitative calcium entry revised. Cell Calcium 11 (1990) 611-624
35. 2+ fluxes in mitochondria, microsomes and plasma membrane vesicles. Chem. Biol. Interact. 147 (2004) 49-63
36. Schanne F.A.X., and Moore L. Liver plasma membrane calcium transport. J. Biol. Chem. 261 (1986) 9886-9889
37. 2+ inflow pathway in hepatocytes stimulated by thapsigargin is similar to that activated by vasopressin. Biochem. Pharmacol. 45 (1993) 2163-2165
38. Thastrup O., Dawson A.P., Scharff O., Foder B., Cullen P.J., Drobak B.K., Bjerrum P.J., Christensen S.B., and Hanley M.R. Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage. Agents Actions 27 (1989) 17-23
39. Vakily M., Amer F., Kukulka M.J., and Andhivarothai N. Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. J. Clin. Pharmacol. 45 (2005) 1179-1186
40. Weinblatt M.E. Toxicity of low dose methotrexate in rheumatoid arthritis. J. Rheumatol. 12 (1985) 35-39
41. Yamamoto N.S., Ishii-Iwamoto E.L., and Bracht A. Activation of glycogenolysis by methotrexate. Influence of calcium and inhibitors of hormone action. Biochem. Pharmacol. 44 (1992) 761-767
42. 2+ homeostasis by Bcl-2. J. Biol. Chem. 19 (1999) 33267-33273