Nuclear compartmentalization of FAK and FRNK in cardiac myocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 6, 2006, Pages

  Xian, Ping Yi ^a,b   Zhou, Jibin ^a   Huber, Lu ^a   Qu, Jiaxiang ^a   Wang, Xuejun ^a   Gerdes, A Martin ^a   Li, Faqian ^a,c  

^a UNIVERSITY OF SOUTH DAKOTA   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c SANFORD RESEARCH   (United States)

Author keywords

Cardiac hypertrophy; Focal adhesion kinase; Focal adhesion kinase related nonkinase; Hypertension; Nucleus; Protein kinase C

Indexed keywords

FIBRILLARIN; FOCAL ADHESION KINASE; FOCAL ADHESION RELATED NONKINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN SAM68; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FEMALE; HEART MUSCLE CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; CELL SEPARATION; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA-BINDING PROTEINS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HEART FAILURE, CONGESTIVE; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; MYOCYTES, CARDIAC; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RNA-BINDING PROTEINS; SERINE; TETRADECANOYLPHORBOL ACETATE;

EID: 33744924190     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00659.2005     Document Type: Article

References (23)

1. Albert CJ and Ford DA. Protein kinase C translocation and PKC-dependent protein phosphorylation during myocardial ischemia. Am J Physiol Heart Circ Physiol 276: H642-H650, 1999.
2. Benmerah A, Scott M, Poupon V, and Marullo S. Nuclear functions for plasma membrane-associated proteins? Traffic 4: 503-511, 2003.
3. Bettinger BT, Gilbert DM, and Amberg DC. Actin up in the nucleus. Nat Rev Mol Cell Biol 5: 410-415, 2004.
4. Clark EA and Brugge JS. Integrins and signal transduction pathways: the road taken. Science 268: 233-239, 1995.
5. Fonseca PM, Inoue RY, Kobarg CB, Crosara-Alberto DP, Kobarg J, and Franchini KG. Targeting to C-terminal myosin heavy chain may explain mechanotransduction involving focal adhesion kinase in cardiac myocytes. Circ Res 96: 73-81, 2005.
6. Franchini KG, Torsoni AS, Soares PH, and Saad MJ. Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart. Circ Res 87: 558-565, 2000.
7. Hug H and Sarre TF. Protein kinase C isoenzymes: divergence in signal transduction? Biochem J 291: 329-343, 1993.
8. Johnsen DD, Kacimi R, Anderson BE, Thomas TA, Said S, and Gerdes AM. Protein kinase C isozymes in hypertension and hypertrophy: insight from SHHF rat hearts. Mol Cell Biochem 270: 63-69, 2005.
9. Kadare G, Toutant M, Formstecher E, Corvol JC, Carnaud M, Boutterin MC, and Girault JA. PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation. J Biol Chem 278: 47434-47440, 2003.
10. Kuppuswamy D, Kerr C, Narishige T, Kasi VS, Menick DR, and Cooper G IV. Association of tyrosine-phosphorylated c-Src with the cytoskeleton of hypertrophying myocardium. J Biol Chem 272: 4500-4508, 1997.
11. Laser M, Kasi VS, Hamawaki M, Cooper G IV, Kerr CM, and Kuppuswamy D. Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal. J Biol Chem 273: 24610-24619, 1998.
12. Li F, Wang X, Capasso JM, and Gerdes AM. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol 28: 1737-1746, 1996.
13. Li X, Lee JW, Graves LM, and Earp HS. Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway. EMBO J 17: 2574-2583, 1998.
14. Ma A, Richardson A, Schaefer EM, and Parsons JT. Serine phosphorylation of focal adhesion kinase in interphase and mitosis: a possible role in modulating binding to p130(Cas). Mol Biol Cell 12: 1-12, 2001.
15. Misteli T. Protein dynamics: implications for nuclear architecture and gene expression. Science 291: 843-847, 2001.
16. Nishikawa K, Toker A, Johannes FJ, Songyang Z, and Cantley LC. Determination of the specific substrate sequence motifs of protein kinase C isozymes. J Biol Chem 272: 952-960, 1997.
17. Richard S, Yu D, Blumer K, Hausladen D, Olszowy M, Connelly P, and Shaw A. Association of p62, a multifunctional SH2- and SH3- domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase Cγ-1. Mol Cell Biol 15: 186-197, 1995.
18. Richardson A, Shannon JD, Adams RB, Schaller MD, and Parsons J. Identification of integrin-stimulated sites of serine phosphorylation in FRNK, the separately expressed C-terminal domain of focal adhesion kinase: a potential role for protein kinase A. Biochem J 324: 141-149, 1997.
19. Wells A and Marti U. Signalling shortcuts: cell-surface receptors in the nucleus? Nat Rev Mol Cell Biol 3: 697-702, 2002.
20. Yamakita Y, Totsukawa G, Yamashiro S, Fry D, Zhang X, Hanks SK, and Matsumura F. Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK. J Cell Biol 144: 315-324, 1999.
21. Yi XP, Gerdes AM, and Li F. Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats. Hypertension 39: 1058-1063, 2002.
22. Yi XP, Wang X, Gerdes AM, and Li F. Subcellular redistribution of focal adhesion kinase and its related nonkinase in hypertrophic myocardium. Hypertension 41: 1317-1323, 2003.
23. Yi XP, Zhou J, Baker J, Wang X, Gerdes AM, and Li F. Myocardial expression and redistribution of GRKs in hypertensive hypertrophy and failure. Anat Rec A Discov Mol Cell Evol Biol 282: 13-23, 2005.