Altered folding, turnover, and polarized sorting act in concert to define a novel pathomechanism of congenital sucrase-isomaltase deficiency

Journal of Biological Chemistry

Volumn 281, Issue 20, 2006, Pages 14393-14399

  Keiser, Markus ^a   Alfalah, Marwan ^a   Pröpsting, Marcus J ^a   Castelletti, Deborah ^a   Naim, Hassan Y ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIGENS; BIOLOGICAL MEMBRANES; DISEASES; PATHOLOGY; SOLUBILITY;

CDNA ENCODING; CONGENITAL SUCRASE-ISOMALTASE DEFICIENCY (CSID); MALABSORPTION DISORDER; SECRETORY PROTEINS;

PROTEINS;

ARGININE; COMPLEMENTARY DNA; CYSTEINE; SUCRASE ISOMALTASE;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ARTICLE; BASOLATERAL MEMBRANE; CARBOHYDRATE INTOLERANCE; CELL FUNCTION; CELL SURFACE; CELLULAR DISTRIBUTION; CONGENITAL SUCRASE ISOMALTASE DEFICIENCY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME LOCALIZATION; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; EPITOPE MAPPING; GENE MUTATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; WILD TYPE;

ADULT; AMINO ACID SEQUENCE; ANIMALS; CARBOHYDRATE METABOLISM, INBORN ERRORS; DETERGENTS; ENDOPLASMIC RETICULUM; EPITOPE MAPPING; HUMANS; INTESTINES; MALE; MOLECULAR SEQUENCE DATA; OCTOXYNOL; PROTEIN FOLDING; SEQUENCE HOMOLOGY, AMINO ACID; SUCRASE-ISOMALTASE COMPLEX;

EID: 33744917301     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513631200     Document Type: Article

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