Continuous chromatographic separation of a baclofen precursor (N-Boc-4-[p-chloro-phenyl]-2-pyrrolidone) in a simulated moving bed using a polysaccharide carbamate as chiral stationary phase

Journal of Chromatography A

Volumn 1119, Issue 1-2, 2006, Pages 156-162

  de Veredas, Vinicius ^a   Carpes, Marcos José Sousa ^a   Correia, Carlos Roque Duarte ^a   Santana, Cesar Costapinto ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

(N Boc 4 p chloro phenyl 2 pyrrolidone); Cellulose tris(3,5 dimethylphenylcarbamate); Enantiomer separation; Preparative chromatography; SMB chromatography

Indexed keywords

ADSORPTION; CELLULOSE; COMPUTER SIMULATION; COST EFFECTIVENESS; LIQUID CHROMATOGRAPHY; POLYSACCHARIDES;

(N-BOC-4-[P-CHLORO-PHENYL]-2-PYRROLIDONE); CELLULOSE TRIS(3,5-DIMETHYLPHENYLCARBAMATE); ENANTIOMER SEPARATION; PREPARATIVE CHROMATOGRAPHY; SIMULATED MOVING BED (SMB) CHROMATOGRAPHY;

DRUG PRODUCTS;

2 PYRROLIDONE DERIVATIVE; ALCOHOL; CELLULOSE TRIS(3,5 DIMETHYLPHENYLCARBAMATE); HEXANE; N TERT BUTYLOXYCARBONYL 4 (4 CHLOROPHENYL) 2 PYRROLIDONE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; CHIRALITY; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POLARIMETER; PRIORITY JOURNAL; SIMULATION; ULTRAVIOLET SPECTROPHOTOMETRY;

BACLOFEN; CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ETHANOL; HEXANES; PHENYLCARBAMATES; PYRROLIDINONES; STEREOISOMERISM;

ADSORPTION; CELLULOSE; COST EFFECTIVENESS; DRUGS; LIQUID CHROMATOGRAPHY; POLYSACCHARIDES;

EID: 33744831758     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.01.003     Document Type: Article

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