Airway remodeling in allergen-challenged Brown Norway rats: Distribution of proteoglycans

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 6, 2006, Pages

  Pini, Laura ^a   Torregiani, Chiara ^a   Martin, James G ^a   Hamid, Qutayba ^a   Ludwig, Mara S ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Biglycan; Collagen; Decorin

Indexed keywords

ALLERGEN; BIGLYCAN; COLLAGEN TYPE 1; DECORIN; FORMALDEHYDE; LEUCINE; OVALBUMIN; PROTEOGLYCAN; SODIUM CHLORIDE;

ADVENTITIA; AIRWAY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BREATHING MUSCLE; CONTROLLED STUDY; INCUBATION TIME; MALE; NONHUMAN; NORWAY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RESPIRATORY EPITHELIUM; SENSITIZATION; SMOOTH MUSCLE;

ADJUVANTS, IMMUNOLOGIC; AIRWAY RESISTANCE; ALLERGENS; ANIMALS; BORDETELLA PERTUSSIS; EOSINOPHIL MAJOR BASIC PROTEIN; MALE; OVALBUMIN; PROTEOGLYCANS; RATS; RATS, INBRED BN; REFERENCE VALUES; RESPIRATORY MUCOSA;

EID: 33744811666     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00122.2005     Document Type: Article

References (32)

1. Al Jamal R, Roughley PJ, and Ludwig MS. Effect of glycosaminoglycan degradation on lung tissue viscoelasticity. Am J Physiol Lung Cell Mol Physiol 280: L306-L315, 2001.
2. Bensadoun ES, Burke AK, Hogg JC, and Roberts CR. Proteoglycan deposition in pulmonary fibrosis. Am J Respir Crit Care Med 154: 1819-1828, 1996.
3. Brain JD and Valberg PA. Deposition of aerosol in the respiratory tract. Am Rev Respir Dis 120: 1325-1373, 1979.
4. Bramley AM, Roberts CR, and Schellenberg RR. Collagenase increases shortening of human bronchial smooth muscle in vitro. Am J Respir Crit Care Med 152: 1513-1517, 1995.
5. Chakir J, Shannon J, Molet S, Fukakusa M, Elias J, Laviolette M, Boulet LP, and Hamid Q. Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol 111: 1293-1298, 2003.
6. Du T, Sapienza S, Wang CG, Renzi PM, Pantano R, Rossi P, and Martin JG. Effect of nedocromil sodium on allergen-induced airway responses and changes in the quantity of airway smooth muscle in rats. J Allergy Clin Immunol 98: 400-407, 1996.
7. Evanko SP, Angello JC, and Wight TN. Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 19: 1004-1013, 1999.
8. Fisher LW, Stubbs JT III, and Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl 266: 61-65, 1995.
9. Flood-Page P, Menzies-Gow A, Phipps S, Ying S, Wangoo A, Ludwig MS, Barnes N, Robinson D, and Kay AB. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 112: 1029-1036, 2003.
10. Fust A, LeBellego F, Iozzo RV, Roughley PJ, and Ludwig MS. Alterations in lung mechanics in decorin-deficient mice. Am J Physiol Lung Cell Mol Physiol 288: L159-L166, 2005.
11. Hildebrand A, Romaris M, Rasmussen LM, Heinegard D, Twardzik DR, Border WA, and Ruoslahti E. Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta. Biochem J 302: 527-534, 1994.
12. Huang J, Olivenstein R, Taha R, Hamid Q, and Ludwig MS. Enhanced proteoglycan deposition in the airway wall of atopic asthmatics. Am J Respir Crit Care Med 160: 725-729, 1999.
13. Iozzo RV. Matrix proteoglycans: from molecular design to cellular function. Annu Rev Biochem 67: 609-652, 1998.
14. Johnson PR, Burgess JK, Underwood PA, Au W, Poniris MH, Tamm M, Ge Q, Roth M, and Black JL. Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism. J Allergy Clin Immunol 113: 690-696, 2004.
15. Kolb M, Margetts PJ, Sime PJ, and Gauldie J. Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung. Am J Physiol Lung Cell Mol Physiol 280: L1327-L1334, 2001.
16. Kraft M. The distal airways: are they important in asthma? Eur Respir J 14: 1403-1417, 1999.
17. Macklem PT. A theoretical analysis of the effect of airway smooth muscle load on airway narrowing. Am J Respir Crit Care Med 153: 83-89, 1996.
18. Mead J, Takishima T, and Leith D. Stress distribution in lungs: a model of pulmonary elasticity. J Appl Physiol 28: 596-608, 1970.
19. Minshall EM, Hogg JC, and Hamid QA. Cytokine mRNA expression in asthma is not restricted to the large airways. J Allergy Clin Immunol 101: 386-390, 1998.
20. Minshall EM, Leung DY, Martin RJ, Song YL, Cameron L, Ernst P, and Hamid Q. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 17: 326-333, 1997.
21. Moreno RH, Hogg JC, and Pare PD. Mechanics of airway narrowing. Am Rev Respir Dis 133: 1171-1180, 1986.
22. Palmans E, Kips JC, and Pauwels RA. Prolonged allergen exposure induces structural airway changes in sensitized rats. Am J Respir Crit Care Med 161: 627-635, 2000.
23. Pare PD. Airway hyperresponsiveness in asthma: geometry is not everything! Am J Respir Crit Care Med 168: 913-914, 2003.
24. Potter-Perigo S, Baker C, Tsoi C, Braun KR, Isenhath S, Altman GM, Altman LC, and Wight TN. Regulation of proteoglycan synthesis by leukotriene d4 and epidermal growth factor in bronchial smooth muscle cells. Am J Respir Cell Mol Biol 30: 101-108, 2004.
25. Redington AE, Roche WR, Holgate ST, and Howarth PH. Co-localization of immunoreactive transforming growth factor-beta 1 and decorin in bronchial biopsies from asthmatic and normal subjects. J Pathol 186: 410-415, 1998.
26. Roberts CR. Is asthma a fibrotic disease? Chest 107: 111S-117S, 1995.
27. Roche WR, Beasley R, Williams JH, and Holgate ST. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1: 520-524, 1989.
28. Roughley PJ, White RJ, Magny MC, Liu J, Pearce RH, and Mort JS. Non-proteoglycan forms of biglycan increase with age in human articular cartilage. Biochem J 295: 421-426, 1993.
29. Sapienza S, Du T, Eidelman DH, Wang NS, and Martin JG. Structural changes in the airways of sensitized brown Norway rats after antigen challenge. Am Rev Respir Dis 144: 423-427, 1991.
30. Tufvesson E and Westergren-Thorsson G. Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration. J Cell Sci 116: 4857-4864, 2003.
31. Venkatesan N, Ebihara T, Roughley PJ, and Ludwig MS. Alterations in large and small proteoglycans in bleomycin-induced pulmonary fibrosis in rats. Am J Respir Crit Care Med 161: 2066-2073, 2000.
32. Wang CG, Du T, Xu LJ, and Martin JG. Role of leukotriene D4 in allergen-induced increases in airway smooth muscle in the rat. Am Rev Respir Dis 148: 413-417, 1993.