Efficient synthesis of 2-substituted indoles based on palladium(II) acetate/tri-tert-butylphosphine-catalyzed alkynylation/amination of 1,2-dihalobenzenes

Advanced Synthesis and Catalysis

Volumn 348, Issue 7-8, 2006, Pages 846-850

  Tang, Zhen Yu ^a   Hu, Qiao Sheng ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

1,2 dihalobenzenes; Alkynylation; Amination; Indoles; Palladium; Phosphane ligands

Indexed keywords

EID: 33744810847     PISSN: 16154150     EISSN: 15213897     Source Type: Journal    
DOI: 10.1002/adsc.200606022     Document Type: Article

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48. [10]). In addition, tri-tert-butylphosphine is cheaper than the sterically hindered 1,3-bis(2,6-diisopropylphenyl)imidazolium chloride: For example, the prices from the 2004-2006 Strem's catalog: tri-tert-phosphine: $ 37.0/g; 1,3-bis(2,6-diisopropylphenyl)imidazolium chloride: $ 58.0/500 mg.