Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 290, Issue 6, 2006, Pages

  Song, Jin ^a   Kost Jr , Curtis K ^a   Martin, Douglas S ^a  

^a UNIVERSITY OF SOUTH DAKOTA   (United States)

Author keywords

Angiotensin; Hypertension; Kidney; Sex steroids

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; MESSENGER RNA; TESTOSTERONE; THIOBUTABARBITAL;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART RATE; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY VASCULAR RESISTANCE; MALE; MEAN ARTERIAL PRESSURE; NEW ZEALAND; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TESTOSTERONE BLOOD LEVEL; URINE VOLUME; WESTERN BLOTTING;

AGE FACTORS; ANDROGENS; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BODY WEIGHT; ENALAPRIL; GENE EXPRESSION; HEART RATE; HYPERTENSION; KIDNEY; MALE; ORCHIECTOMY; ORGAN SIZE; RATS; RATS, INBRED STRAINS; RECEPTOR, ANGIOTENSIN, TYPE 1; RENAL ARTERY; RENAL CIRCULATION; TESTOSTERONE;

EID: 33744808519     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00364.2005     Document Type: Article

References (46)

1. Arendshorst WJ, Chatziantoniou C, and Daniels FH. Role of angiotensin in the renal vasoconstriction observed during the development of genetic hypertension. Kidney Int 30: S92-S96, 1990.
2. Ashton N and Balment RJ. Sexual dimorphism in renal function and hormonal status of New Zealand genetically hypertensive rats. Acta Endocrinol 124: 91-97, 1991.
3. Baiardi G, Macova M, Armando I, Ando H, Tyurmin D, and Saavedra J. Estrogen upregulates renal angiotensin II AT1 and AT2 receptors in the rat. Regul Pept 124: 7-17, 2005.
4. Baylis C. Age dependent glomerular damage in the rat. J Clin Invest 94: 1823-1829, 1994.
5. Cambotti L, Cole F, Gerall A, Frohlich E, and MacPhee A. Neonatal gonadal hormones and blood pressure in the spontaneously hypertensive rat. Am J Physiol Endocrinol Metab 247: E258-E264, 1984.
6. Chen YF, Naftilan AJ, and Oparil S. Androgen dependent angiotensinogen and renin messenger RNA expression in hypertensive rats. Hypertension 19: 456-463, 1992.
7. Chen YF and Meng QC. Sexual dimorphism of blood pressure in spontaneously hypertensive rats is androgen dependent. Life Sci 48: 85-96, 1991.
8. Chrissobolis S, Budzyn K, Marley PD, and Sobey CG. Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo. Stroke 35: 2200-2205, 2004.
9. DiBona GF. Peripheral and central interactions between the renin-angiotensin system and the renal sympathetic nerves in control of renal function. Ann NY Acad Sci 940: 395-406, 2001.
10. DiBona GF. The sympathetic nervous system and hypertension: recent developments. Hypertension 43: 147-150, 2004.
11. Dubey RK, Oparil S, Imthurn B, and Jackson EK. Sex hormones and hypertension. Cardiovasc Res 53: 688-708, 2002.
12. Ellison KE, Ingelfinger JR, Pivor M, and Dzau VJ. Androgen regulation of rat renal angiotensinogen messenger RNA expression. J Clin Invest 83: 1941-1945, 1989.
13. Fortepiani LA, Yanes L, Zhang H, Racusen LC, and Reckelhoff JF. Role of androgens in mediating renal injury in aging SHR. Hypertension 42: 952-955, 2003.
14. Fortepiani LA, Zhang H, Racusen L, Racusen LC, and Reckelhoff JF. Characterization of an animal model of postmenopausal hypertension in spontaneously hypertensive rats. Hypertension 41: 640-645, 2003.
15. Ganten U, Schroder G, Witt M, Zimmermann. F, Ganten D, and Stock G. Sexual dimorphism of blood pressure in spontaneously hypertensive rats: effect of anti-androgen treatment. J Hypertens 7: 721-726, 1989.
16. Hall JE. Historical perspective of the renin-angiotensin system. Mol Biotechnol 24: 27-39, 2003.
17. Hall JE. The kidney, hypertension, and obesity. Hypertension 41: 625-633, 2003.
18. Hall JE, Guyton AC, and Mizelle HL. Role of the renin-angiotensin system in control of sodium excretion and arterial pressure. Acta Physiol Scand Suppl 591: 48-62, 1990.
19. Harrap SB. A developmental genetic mechanism involving angiotensin in spontaneously hypertensive rats. Clin Exp Pharmacol Physiol Suppl 19: 19-22, 1992.
20. Hinojosa Laborde C, Craig T, Zheng W, Ji H, Haywood JR, and Sandberg K. Ovariectomy augments hypertension in aging female Dahl salt-sensitive rats. Hypertension 44: 405-409, 2004.
21. Jenkins C, Salisbury R, and Ely D. Castration lowers and testosterone restores blood pressure in several rat strains on high-sodium diet. Clin Exp Hypertens 16: 611-625, 1994.
22. Ji H, Menini S, Mok K, Zheng W, Pesce C, Kim J, Mulroney S, and Sandberg K. Gonadal steroid regulation of renal injury in renal wrap hypertension. Am J Physiol Renal Physiol 288: F513-F520, 2005.
23. Kanashiro CA and Khalil RA. Gender-related distinctions in protein kinase C activity in rat vascular smooth muscle. Am J Physiol Cell Physiol 280: C34-C45, 2001.
24. Kang AK and Miller JA. Effects of gender on the renin angiotensin system, blood pressure and renal function. Curr Hypertens Rep 4: 143-151, 2002.
25. Karanian JW and Ramwell PW. Effect of gender and sex steroids on the contractile response of canine coronary and renal blood vessels. J Cardiovasc Pharmacol 27: 312-319, 1996.
26. Kost CK, Herzer WA, Li P, and Jackson EK. Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats. J Pharmacol Exp Ther 269: 82-88, 1994.
27. Leung PS, Wong TP, Chung YW, and Chan HC. Androgen-dependent expression of AT1 receptor and its regulation of anion secretion in rat epididymis. Cell Biol Int 26: 117-122, 2002.
28. Liu H, Ledingham JM, Mullaney I, and Laverty R. Endothelial function in mesenteric resistance arteries from the genetically hypertensive rat. Clin Exp Pharmacol Physiol 29: 405-411, 2002.
29. Olsen ME, Hall JE, Montani JP, and Guyton AC. Angiotensin II natriuresis and antinatriuresis: role of renal artery pressure, renal hemodynamics, and tubular reabsorption. Acta Med Scand Suppl 693: 81-88, 1985.
30. Quan A, Chakravarty S, Chen JK, Chen JC, Loleh S, Saini N, Harris RC, Capdevila J, and Quigley R. Androgens augment proximal tubule transport. Am J Physiol Renal Physiol 287: F452-F459, 2004.
31. Reckelhoff JF. Gender differences in the regulation of blood pressure. Hypertension 37: 1199-1208, 2001.
32. Reckelhoff JF. Sex steroids, cardioavascular disease and hypertension. Hypertension 45: 170-174, 2005.
33. Reckelhoff JF, Zhang H, and Granger J. Decline in renal hemodynamic function in aging SHR: role of androgens. Hypertension 30: 677-681, 1997.
34. Reckelhoff JF, Zhang H, and Srivastava K. Gender differences in the development of hypertension in spontaneously hypertensive rats. Role of the renin angiotensin system. Hypertension 35: 480-483, 2000.
35. Reckelhoff JF, Zhang H, Srivastava K, and Granger JP. Gender differences in hypertension in spontaneously hypertensive rats. Role of androgens and androgen receptor. Hypertension 34: 920-923, 1999.
36. Reckelhoff JF, Zhang J, and Granger JP. Testosterone exacerbates hypertension and reduces pressure natriuresis in male spontaneously hypertensive rats. Hypertension 31: 435-439, 1998.
37. Rettig R, Bandelow N, Patschan O, Kuttler B, Frey B, and Uber A. The importance of the kidney in primary hypertension: insights from cross-transplantation. J Hum Hypertens 10: 641-644, 1996.
38. Rodrigo MC, Martin DS, Redetzke RA, and Eyster KM. A method for the extraction of high quality RNA and protein from single small samples of arteries and veins preserved in RNA later. J Pharmacol Toxicol Methods 47: 87-92, 2002.
39. Sander S, Rettig R, and Ehrig B. Role of the native kidney in experimental post-transplantation hypertension. Pflügers Arch 431: 971-976, 1996.
40. Silva-Antonialli M, Tostes R, Fernandez L, Chadi DF, Cadamine E, Carvalho M, Fortes Z, and Nigro D. A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats. Cardiovasc Res 62: 587-593, 2004.
41. Simpson FO, Ledingham JM, and Phelan EL. Body sodium level in hypertensive and normotensive rats: effects of dietary sodium levels and sodium loads. J Cardiovasc Pharmacol 6 Suppl 1: S121-S125, 1984.
42. Simpson FO and Phelan EL. Hypertension in the genetically hypertensive strain. In: Handbook of Hypertension, edited by deJong W. New York: Elsevier, 1984, p. 200-223.
43. Tatchum-Talom R, Eyster KM, and Martin DS. Sexual dimorphism in angiotensin II induced hypertension and vascular alterations. Can J Physiol Pharmacol 83: 413-422, 2005.
44. Wagner D, Metzger R, Paul M, Ludwig G, Suzuki F, Takahashi S, Murakami K, and Ganten G. Andogen dependence and tissue specificity of renin messenger RNA expression in mice. J Hypertens 8: 45-52, 1990.
45. Wangensteen R, Moreno J, Sainz J, Rodriguez-Gomez W, Chamorro V, de Dios Luna J, Osuna A, and Vargas F. Gender difference in the role of endothelium derived relaxing factors modulating renal vascular reactivity. Eur J Pharmacol 486: 281-288, 2004.
46. Xue B, Pamidimukkala J, and Hay M. Sex differences in the development of angiotensin II-induced hypertension in conscious mice. Am J Physiol Heart Circ Physiol 288: H2177-H2184, 2005.