Characterization and quantitative analysis of xanthones in gamboges

Chinese Journal of Natural Medicines

Volumn 4, Issue 3, 2006, Pages 210-214

  Han, Quan Bin ^a   Song, Jing Zheng ^a   Qiao, Chun Feng ^a   Xu, Hong Xi ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Characterization analysis; Gamboge; Garcinia hanburyi; Quantitative analysis; Xanthones

Indexed keywords

30 HYDROXYGAMBOGIC ACID; BIOCHEMICAL MARKER; GAMBOGENIC ACID; HERBACEOUS AGENT; ISOGAMBOGENIC ACID; ISOGAMBOGIC ACID; ISOMORELLIC ACID; MORELLIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ARTICLE; CHINA; DRUG DETERMINATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; GARCINIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDIA; LIQUID CHROMATOGRAPHY; QUALITY CONTROL; QUANTITATIVE ANALYSIS; SAMPLING; STRUCTURE ANALYSIS; VALIDATION PROCESS;

EID: 33744805360     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Ampofo AS, Waterman GP. Xanthones from three Garcinia species [J]. Phytochemistry, 1986, 25 (10):2351-2355.
2. Tandon RN, Srivastava OP, Baslas RK, et al. Preliminary investigation on the antimicrobial activity of a phytochemical, xanthochymol from the fruits of Garcinia xanthochymus Hook. f. [J]. Curr Sci, 1980, 49:472-473.
3. Gopalakrishnan C, Banumathi B, Sureshm G. Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives[J]. J Nat Prod, 1997, 60 (5):519-524.
4. Weng JR, Lin CN, Tsao LT, et al. Novel and anti-inflammatory constituents of Garcinia subelliptica [J]. Chem Eur J, 2003, 9 (9): 1958-1963.
5. Gustafson KR, Blunt JW, Munro MHG, et al. The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia liningstonei, Garicinia ovalifolia, and Clusia rosea [J]. Tetrahedron, 1992, 48 (46):10093-10102.
6. Guo QL, Zhao L, You QD, et al. Gambogic acid inducing apoptosis in human gastric adenocarcinom SGC-7901 cells[J]. Chin J Nat Med, 2004, 2 (2):106-110.
7. Guo QL, You QD, Wu ZQ, et al. General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice[J]. Acta Pharmacol Sin, 2004, 25:769-774.
8. Zhao L, Guo QL, You QD, et al. Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells[J]. Biol Pharm Bull, 2004, 27 (7): 998-1003.
9. Wu ZQ, Guo QL, You QD, et al. Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells[J]. Biol Pharm Bull, 2004, 27 (11):1769-1774.
10. Lin LJ, Lin LZ, Pezzuto JM, et al. Isogambogic acid and isomorellinol from Garcinia hanburyi [J]. Magn Reson Chem, 1993, 31:340-347.
11. Asano J, Chiba K, Tada M, et al. Cytotoxic xanthones from Garcinia hanburyi[J]. Phytochemistry, 1996, 41 (1):815-820.
12. Zhang HZ, Kasibhatia S, Wang Y, et al. Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay[J]. Bioorg Med Chem, 2004, 12(2): 309-317.
13. Liu WY, Feng F, Chen YS, et al. Studies on the structure of alkaline degradation of gambogic acid[J]. Chin J Nat Med, 2004, 2 (2), 75-77.
14. Han QB, Cheung S, Tai J, et al. Stability and cytotoxicity of gambogic acid and its derivative, gambogoic acid[J]. Biol Pharm Bull, 2005, 28 (12), 2335-2337.
15. Zhang X, Liu WY, Feng F, et al. HPLC fingerprinting of gamboge [J]. Chin J Pharm, 2003, 34 (12):605-606.
16. Yang H, Cong XD, Jiang WL, et al. Determination of the content of gambogic acid and its dervatives in gamboge by ELSD[J]. J China Pharm Univ, 1999, 30 (3):202-203.
17. Han QB, Wang YL, Yang L, et al. Cytotoxic xanthones from the resin of Garcinia hanburyi[J]. Chem Pharm Bull, 2006, 54(2): 265-267.
18. Han QB, Yang L, Wang YL, et al. A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges [J]. Chem Biodivers, 2006, 3:101-105.