Radiation exposure impairs luteinizing hormone signal transduction and steroidogenesis in cultured human Leydig cells

Toxicological Sciences

Volumn 91, Issue 2, 2006, Pages 550-556

  Sivakumar, Ramadoss ^a   Sivaraman, Puliyangudi Balakrishnan ^b   Mohan Babu, Narayanasami ^b   Jainul Abideen, Ibrahim Mohamed ^b   Kalliyappan, Perumal ^b   Balasubramanian, Karundevi ^a  

^a UNIVERSITY OF MADRAS   (India)

^b MADRAS MEDICAL COLLEGE   (India)

Author keywords

Gamma radiation; Human Leydig cell; LH receptor expression; LH signaling; Steroidogenesis

Indexed keywords

CYCLIC AMP; ESTRADIOL; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA;

ADVANCED CANCER; ARTICLE; CANCER PATIENT; CELL CULTURE; CELL STIMULATION; CONTROLLED STUDY; GAMMA RADIATION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; ISOLATION AND PURIFICATION; LEYDIG CELL; MALE; PROSTATE CARCINOMA; PROTEIN EXPRESSION; PROVOCATION TEST; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; RNA ISOLATION; SIGNAL TRANSDUCTION; STEROIDOGENESIS;

17-HYDROXYSTEROID DEHYDROGENASES; 3-HYDROXYSTEROID DEHYDROGENASES; AGED; CELL SURVIVAL; CELLS, CULTURED; CHORIONIC GONADOTROPIN; CYTOCHROME P-450 ENZYME SYSTEM; ESTRADIOL; GAMMA RAYS; GENE EXPRESSION REGULATION; HUMANS; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MIDDLE AGED; RECEPTORS, LH; RNA, MESSENGER; SIGNAL TRANSDUCTION; TESTOSTERONE;

EID: 33744792332     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj178     Document Type: Article

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