Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes

Journal of Medicinal Chemistry

Volumn 49, Issue 11, 2006, Pages 3244-3250

  Carroll, F Ivy ^a   Hu, Xingding ^a   Navarro, Hernán A ^a   Deschamps, Jeffrey ^b   Abdrakhmanova, Galya R ^c   Damaj, M Imad ^c   Martin, Billy R ^c  

^a RTI INTERNATIONAL   (United States)

^b NAVAL RESEARCH LABORATORY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE; NICOTINIC RECEPTOR; PYRIDO[3,4 B]HOMOTROPANE; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERISM; NONHUMAN; RAT; STEREOCHEMISTRY; TAIL FLICK TEST;

ANALGESICS; ANIMALS; CELL LINE; CEREBRAL CORTEX; CRYSTALLOGRAPHY, X-RAY; DISCRIMINATION LEARNING; MALE; NEURONS; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PAIN MEASUREMENT; PATCH-CLAMP TECHNIQUES; PYRIDINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, NICOTINIC; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TROPANES;

EID: 33744789408     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060122n     Document Type: Article

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