Baseline and stimulated turnover of cell surface c-Kit expression in different types of human mast cells

Experimental Dermatology

Volumn 15, Issue 7, 2006, Pages 530-537

  Babina, Magda ^a   Rex, Claudia ^a   Guhl, Sven ^a   Thienemann, Friedrich ^a   Artuc, Metin ^a   Henz, Beate M ^a   Zuberbier, Torsten ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

c Kit; Differentiation; Mast cells; Mastocytosis; Protein turnover

Indexed keywords

BETA1 INTEGRIN; CELL SURFACE RECEPTOR; CYCLOHEXIMIDE; DACTINOMYCIN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 3; STEM CELL FACTOR;

ARTICLE; CELL INTERACTION; CELL MATURATION; CELL STIMULATION; CELL SURFACE; CELL TYPE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MAST CELL; PROTEIN BINDING; PROTEIN EXPRESSION; SKIN CELL; WESTERN BLOTTING;

ANTIGENS, CD; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; CYCLOHEXIMIDE; DACTINOMYCIN; DOWN-REGULATION; ENDOCYTOSIS; FLOW CYTOMETRY; HUMANS; MAST CELLS; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-KIT; PYRIMIDINES; STEM CELL FACTOR; TETRADECANOYLPHORBOL ACETATE;

EID: 33744787111     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2006.00446.x     Document Type: Article

References (34)

1. Ashman L K. The biology of stem cell factor and its receptor c-Kit. Int J Biochem Cell Biol 1999: 31: 1037-1051.
2. Rö;nnstrand L. Signal transduction via the stem cell factor receptor/c-Kit Cell Mol Life Sci 2004 61 2535-2548
3. Roskoski R Jr. Signaling by Kit protein-tyrosine kinase -the stem cell factor receptor. Biochem Biophys Res Commun 2005: 337: 1-13.
4. Lyman S D, Jacobsen S E. c-kit ligand and Flt3 ligand: Stem/progenitor cell factors with overlapping yet distinct activities. Blood 1998: 91: 1101-1134.
5. Kitamura Y, Hirotab S. Kit as a human oncogenic tyrosine kinase. Cell Mol Life Sci 2004: 61: 2924-2931.
6. Heinrich M C, Blanke C D, Druker B J, Corless C L. Inhibition of KIT tyrosine kinase activity: A novel molecular approach to the treatment of KIT-positive malignancies. J Clin Oncol 2002: 20: 1692-1703.
7. Fletcher J A. Role of KIT and platelet-derived growth factor receptors as oncoproteins. Semin Oncol 2004: 31: 4-11.
8. Miettinen M, Lasota J. KIT (CD117): A review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation. Appl Immunohistochem Mol Morphol 2005: 13: 205-220.
9. Grabbe J, Welker P, Dippel E, Czarnetzki B M. Stem cell factor, a novel cutaneous growth factor for mast cells and melanocytes. Arch Dermatol Res 1994: 287: 78-84.
10. Metcalfe D D, Baram D, Mekori Y A. Mast cells. Physiol Rev 1997: 77: 1033-1079.
11. Iwaki S, Tkaczyk C, Metcalfe D D, Gilfillan A M. Roles of adaptor molecules in mast cell activation. Chem Immunol Allergy 2005: 87: 43-58.
12. Bischoff S C, Dahinden C A. c-kit ligand: A unique potentiator of mediator release by human lung mast cells. J Exp Med 1992: 175: 237-244.
13. Furitsu T, Tsujimura T, Tono T et al. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 1993: 92: 1736-1744.
14. Yee N S, Langen H, Besmer P. Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells. J Biol Chem 1993: 268: 14189-14201.
15. Yee N S, Hsiau C W, Serve H, Vosseller K, Besmer P. Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3′-kinase, and protein kinase C. J Biol Chem 1994: 269: 31991-31998.
16. Baghestanian M, Agis H, Bevec D et. al. Stem cell factor-induced. downregulation of c-kit in human lung mast cells and HMC-1 mast cells. Exp Hematol 1996: 24: 1377-1386.
17. Shimizu Y, Ashman L K, Du Z, Schwartz L B. Internalization of Kit together with stem cell factor on human fetal liver-derived mast cells: new protein and RNA synthesis are required for reappearance of Kit. J Immunol 1996: 156: 3443-3449.
18. Tsujimura T, Morii E, Nozaki M et al. Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice. Blood 1996: 88: 1225-1233.
19. Vandenbark G R, Chen Y, Friday E et al. Complex regulation of human c-kit transcription by promoter repressors, activators, and specific myb elements. Cell Growth Differ 1996: 7: 1383-1392.
20. Huang S, Jean D, Luca M, Tainsky M A, Bar-Eli M. Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis. EMBO J 1998: 17: 4358-5369.
21. Ratajczak M Z, Perrotti D, Melotti P et al. Myb and ets proteins are candidate regulators of c-kit expression in human hematopoietic cells. Blood 1998: 91:1934-1946
22. Krosl G, He G, Lefrancois M et al. Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells. J Exp Med 1998: 188: 439-450.
23. Park G H, Plummer H K III, Krystal G W. Selective Sp1 binding is critical for maximal activity of the human c-kit promoter. Blood 1998: 92: 4138 4149.
24. Lecuyer E, Herblot S, Saint-Denis M et al. The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1. Blood 2002: 100: 2430-2440.
25. Felli N, Fontana L, Pelosi E et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A 2005: 102: 18081-18086.
26. Cruz A C, Frank B T, Edwards S T, Dazin P F, Peschon J J, Fang K C. Tumor necrosis factor-alpha-converting enzyme controls surface expression of c-Kit and survival of embryonic stem cell-derived mast cells. J Biol Chem 2004: 279: 5612-5620.
27. Babina M, Guhl S, Stärke A, Kirchhof L, Zuberbier T, Henz B M. Comparative cytokine profile of human skin mast cells from two compartments -strong resemblance with monocytes at baseline, but induction of IL-5 by IL-4 priming. J Leukoc Biol 2004: 75: 244-252.
28. Butterfield J H, Weiler D, Dewald G, Gleich G J. Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk Res 1988: 12: 345-355.
29. Weber S, Babina M, Krüger-Krasagakes S.Grützkau A.Henz B M. A subclone (5C6) of the human mast cell line HMC-1 represents a more differentiated phenotype than the original cell line. Arch Dermatol Res 1996: 288: 778-782.
30. Kirshenbaum A S, Akin C, Wu Y et al. Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcεRI or FcγRI. Leuk Res 2003: 27: 677-682.
31. Babina M, Henz B M. All-trans retinoic acid down-regulates expression and function of β 2 integrins by human monocytes: Opposite effects on monocytic cell lines. Eur J Immunol 2003: 33: 616-625.
32. Artuc M, Hermes B, Steckelings U M, Grützkau A, Henz B M. Mast cells and their mediators in cutaneous wound healing -active participants or innocent bystanders? Exp Dermatol 1999: 8: 1-16.
33. Maurer M, Theoharides T, Granstein R D et al. What is the physiological function of mast cells? Exp Dermatol 2003: 12: 886-891.
34. Riekki R, Harvima I T, Jukkola A, Risteli J, Oikarinen A. The production of collagen and the activity of mast-cell chymase increase in human skin after irradiation therapy. Exp Dermatol 2004: 13: 364-371.