-
3
-
-
0036184605
-
Treatment and prevention of intraepithelial neoplasia an important target for accelerated new agent development
-
O'Shaughnessy JA, Kelloff GJ, Gordon GB, et al Treatment and prevention of intraepithelial neoplasia an important target for accelerated new agent development. Clin Cancer Res 2002;8:314-46.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 314-346
-
-
O'Shaughnessy, J.A.1
Kelloff, G.J.2
Gordon, G.B.3
-
4
-
-
0035953705
-
Molecular markers of the risk of oral cancer
-
Lippman SM, Hong WK. Molecular markers of the risk of oral cancer (editorial). N Engl J Med 2001;344: 1323-6.
-
(2001)
N Engl J Med
, vol.344
, pp. 1323-1326
-
-
Lippman, S.M.1
Hong, W.K.2
-
5
-
-
0343091242
-
Predicting cancer development in oral leukoplakia: Ten years of translational research
-
Lee JJ, Hong WK, Hittelman WN, et al. Predicting cancer development in oral leukoplakia: ten years of translational research. Clin Cancer Res 2000;6:1702-10.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1702-1710
-
-
Lee, J.J.1
Hong, W.K.2
Hittelman, W.N.3
-
6
-
-
33744808652
-
Retinoids, carotenoids, and micronutrients
-
7th ed. DeVita VT, Jr., Hellman S, Rosenberg SA, editors. Philadelphia: Lippincott Williams & Wilkins
-
Mayne ST, Lippman SM. Retinoids, carotenoids, and micronutrients. 7th ed. In: DeVita VT, Jr., Hellman S, Rosenberg SA, editors. Cancer: principles and practice of oncology. Philadelphia: Lippincott Williams & Wilkins: 2005. p. 521-36.
-
(2005)
Cancer: Principles and Practice of Oncology
, pp. 521-536
-
-
Mayne, S.T.1
Lippman, S.M.2
-
7
-
-
0022916262
-
13-Cis-retinoic acid in the treatment of oral leukoplakia
-
Hong WK, Endicott J, Itri LM, et al. 13-Cis-retinoic acid in the treatment of oral leukoplakia. N Engl J Med 1986;315:1501-5.
-
(1986)
N Engl J Med
, vol.315
, pp. 1501-1505
-
-
Hong, W.K.1
Endicott, J.2
Itri, L.M.3
-
8
-
-
0025091456
-
Prevention of second primary tumors with isotretinoin in squamous cell carcinoma of the head and neck
-
Hong WK, Lippman SM, Itri L, et al. Prevention of second primary tumors with isotretinoin in squamous cell carcinoma of the head and neck. N Engl J Med 1990;323:795-801.
-
(1990)
N Engl J Med
, vol.323
, pp. 795-801
-
-
Hong, W.K.1
Lippman, S.M.2
Itri, L.3
-
9
-
-
0027395951
-
Comparison of low-dose isotretinoin with β-carotene to prevent oral carcinogenesis
-
Lippman SM, Batsakis JG, Toth BB, et al. Comparison of low-dose isotretinoin with β-carotene to prevent oral carcinogenesis. N Engl J Med 1993;328:15-20.
-
(1993)
N Engl J Med
, vol.328
, pp. 15-20
-
-
Lippman, S.M.1
Batsakis, J.G.2
Toth, B.B.3
-
10
-
-
33645510414
-
Reducing the "risk" of chemoprevention: Defining and targeting high risk-2005 AACR Cancer Research and Prevention Foundation Award Lecture
-
Lippman SM, Lee JJ. Reducing the "risk" of chemoprevention: defining and targeting high risk-2005 AACR Cancer Research and Prevention Foundation Award Lecture. Cancer Res 2006;66:2893-903.
-
(2006)
Cancer Res
, vol.66
, pp. 2893-2903
-
-
Lippman, S.M.1
Lee, J.J.2
-
12
-
-
0032556189
-
Phenotype and genotype in advanced premalignant head and neck lesions after chemopreventive therapy
-
Mao L, El-Naggar AK, Papadimitrakopoulou V, et al. Phenotype and genotype in advanced premalignant head and neck lesions after chemopreventive therapy. J Natl Cancer Inst 1998;90:1545-51.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1545-1551
-
-
Mao, L.1
El-Naggar, A.K.2
Papadimitrakopoulou, V.3
-
13
-
-
0029044431
-
Suppression of retinoic acid receptor p in oral premalignant lesions and its upregulation by isotretinoin
-
Lotan R, Xu C, Lippman SM, et al. Suppression of retinoic acid receptor p in oral premalignant lesions and its upregulation by isotretinoin. N Engl J Med 1995;332:1405-10.
-
(1995)
N Engl J Med
, vol.332
, pp. 1405-1410
-
-
Lotan, R.1
Xu, C.2
Lippman, S.M.3
-
14
-
-
0032907350
-
Role of retinoic acid receptor overexpression in sensitivity to fenretinide and tumorigenicity of human ovarian carcinoma cells
-
Pergolizzi R, Appierto V, Crosti M, et al. Role of retinoic acid receptor overexpression in sensitivity to fenretinide and tumorigenicity of human ovarian carcinoma cells. Int J Cancer 1999;81:829-34.
-
(1999)
Int J Cancer
, vol.81
, pp. 829-834
-
-
Pergolizzi, R.1
Appierto, V.2
Crosti, M.3
-
15
-
-
1842450528
-
Nuclear retinoid receptors are involved in N-(4-hydroxyphenyl) retinamide (fenretinide)-induced gene expression and growth inhibition in HL-60 acute myeloid leukemia cells
-
Ozpolat B, Tari AM, Mehta K, Lopez-Berestein G. Nuclear retinoid receptors are involved in N-(4-hydroxyphenyl) retinamide (fenretinide)-induced gene expression and growth inhibition in HL-60 acute myeloid leukemia cells. Leuk Lymphoma 2004;45: 979-85.
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 979-985
-
-
Ozpolat, B.1
Tari, A.M.2
Mehta, K.3
Lopez-Berestein, G.4
-
16
-
-
0028787351
-
Retinoids and apoptosis: Implications for cancer chemoprevention and therapy
-
Lotan R. Retinoids and apoptosis: implications for cancer chemoprevention and therapy. J Natl Cancer Inst 1995;87:1655-7.
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1655-1657
-
-
Lotan, R.1
-
17
-
-
4444255936
-
Fenretinide activates a distinct apoptotic pathway
-
Dmitrovsky E. Fenretinide activates a distinct apoptotic pathway. J Natl Cancer Inst 2004;96:1264-5.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1264-1265
-
-
Dmitrovsky, E.1
-
18
-
-
1542359577
-
Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells
-
Appierto V, Villani MG, Cavadini E, Lotan R, Vinson C, Formelli F. Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells. Cell Death Differ 2004;11:270-9.
-
(2004)
Cell Death Differ
, vol.11
, pp. 270-279
-
-
Appierto, V.1
Villani, M.G.2
Cavadini, E.3
Lotan, R.4
Vinson, C.5
Formelli, F.6
-
19
-
-
10744230535
-
Heterogeneous role of caspase-8 in fenretinide-induced apoptosis in epithelial ovarian carcinoma cell lines
-
Kalli KR, Devine KE, Cabot MC, et al. Heterogeneous role of caspase-8 in fenretinide-induced apoptosis in epithelial ovarian carcinoma cell lines. Mol Pharmacol 2003;64:1434-43.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1434-1443
-
-
Kalli, K.R.1
Devine, K.E.2
Cabot, M.C.3
-
20
-
-
27144477320
-
N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(κ)B(α) kinase and nuclear factor-κB-regulated gene products
-
Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB. N-(4-hydroxyphenyl) retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(κ)B(α) kinase and nuclear factor-κB-regulated gene products. Cancer Res 2005;65:9555-65.
-
(2005)
Cancer Res
, vol.65
, pp. 9555-9565
-
-
Shishodia, S.1
Gutierrez, A.M.2
Lotan, R.3
Aggarwal, B.B.4
-
21
-
-
0032922598
-
Retinoid receptor-dependent and -independent effects of N-(4-hydroxyphenyl)retinamide in F9 embryonal carcinoma cells
-
Clifford JL, Menter DG, Wang M, Lotan R, Lippman SM. Retinoid receptor-dependent and -independent effects of N-(4-hydroxyphenyl)retinamide in F9 embryonal carcinoma cells. Cancer Res 1999;59:14-8.
-
(1999)
Cancer Res
, vol.59
, pp. 14-18
-
-
Clifford, J.L.1
Menter, D.G.2
Wang, M.3
Lotan, R.4
Lippman, S.M.5
-
22
-
-
0027332981
-
N-(4-hydroxyphenyl) retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid
-
Delia D, Aiello A, Lombardi L, et al. N-(4-hydroxyphenyl) retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid. Cancer Res 1993;53:6036-41.
-
(1993)
Cancer Res
, vol.53
, pp. 6036-6041
-
-
Delia, D.1
Aiello, A.2
Lombardi, L.3
-
23
-
-
0028840629
-
N-(4-hydroxyphenyl)retinamide (4-HPR)-mediated biological actions involve retinoid receptor-independent pathways in human breast carcinoma
-
Sheikh MS, Shao ZM, Li XS, et al. N-(4-hydroxyphenyl)retinamide (4-HPR)-mediated biological actions involve retinoid receptor-independent pathways in human breast carcinoma. Carcinogenesis 1995;16:2477-86.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2477-2486
-
-
Sheikh, M.S.1
Shao, Z.M.2
Li, X.S.3
-
24
-
-
0029887265
-
Differential induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in human head and neck squamous cell carcinoma cell lines
-
Oridate N, Lotan D, Xu XC, Hong WK, Lotan R. Differential induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in human head and neck squamous cell carcinoma cell lines. Clin Cancer Res 1996;2:855-63.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 855-863
-
-
Oridate, N.1
Lotan, D.2
Xu, X.C.3
Hong, W.K.4
Lotan, R.5
-
25
-
-
0023604520
-
NIST measurements of (4-hydroxyphenyl)retinamide in serum
-
MacCrehan WA. NIST measurements of (4-hydroxyphenyl)retinamide in serum. Clin Chem 1987; 33:1585-92.
-
(1987)
Clin Chem
, vol.33
, pp. 1585-1592
-
-
MacCrehan, W.A.1
-
26
-
-
0037480037
-
Breast tissue accumulation of retinamides in a randomized short-term study of fenretinide
-
Sabichi AL, Modiano MR, Lee JJ, et al. Breast tissue accumulation of retinamides in a randomized short-term study of fenretinide. Clin Cancer Res 2003;9: 2400-5.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2400-2405
-
-
Sabichi, A.L.1
Modiano, M.R.2
Lee, J.J.3
-
27
-
-
0029787426
-
4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors
-
Fanjul AN, Delia D, Pierotti MA, Rideout D, Qiu J, Pfahl M. 4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors. J Biol Chem 1996;271:22441-6.
-
(1996)
J Biol Chem
, vol.271
, pp. 22441-22446
-
-
Fanjul, A.N.1
Delia, D.2
Pierotti, M.A.3
Rideout, D.4
Qiu, J.5
Pfahl, M.6
-
28
-
-
0035880941
-
Effects of N-(4-hydroxyphenyl) retinamide on hTERT expression in the bronchial epithelium of cigarette smokers
-
Soria JC, Moon C, Wang L, et al. Effects of N-(4-hydroxyphenyl) retinamide on hTERT expression in the bronchial epithelium of cigarette smokers. J Natl Cancer Inst 2001;93:1257-63.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1257-1263
-
-
Soria, J.C.1
Moon, C.2
Wang, L.3
-
29
-
-
0033406452
-
Estrogen activates telomerase
-
Kyo S, Takakura M, Kanaya T, et al. Estrogen activates telomerase. Cancer Res 1999;59:5917-21.
-
(1999)
Cancer Res
, vol.59
, pp. 5917-5921
-
-
Kyo, S.1
Takakura, M.2
Kanaya, T.3
-
30
-
-
32944481310
-
Chemoprevention of skin carcinogenesis by phenylretinamides: Retinoid receptor independent tumor suppression
-
Xu H, Cheepala S, McCauley E, et al. Chemoprevention of skin carcinogenesis by phenylretinamides: retinoid receptor independent tumor suppression. Clin Cancer Res 2006;12:969-79.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 969-979
-
-
Xu, H.1
Cheepala, S.2
McCauley, E.3
-
31
-
-
0034904794
-
Identification of retinamides that are more potent than N-(4-hydroxyphenyl)-retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells
-
Sun SY, Yue P, Kelloff GJ, et al. Identification of retinamides that are more potent than N-(4-hydroxyphenyl)-retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells. Cancer Epidemiol Biomark Prev 2001;10:595-601.
-
(2001)
Cancer Epidemiol Biomark Prev
, vol.10
, pp. 595-601
-
-
Sun, S.Y.1
Yue, P.2
Kelloff, G.J.3
-
32
-
-
0027360292
-
Five-year administration of fenretinide: Pharmacokinetics and effects on plasma retinol concentrations
-
Formelli F, Clerici M, Campa T, et al. Five-year administration of fenretinide: pharmacokinetics and effects on plasma retinol concentrations. J Clin Oncol 1993;11:2036-42.
-
(1993)
J Clin Oncol
, vol.11
, pp. 2036-2042
-
-
Formelli, F.1
Clerici, M.2
Campa, T.3
-
33
-
-
0033792250
-
Ocular effects of fenretinide, a vitamin A analog, in a chemoprevention trial of bladder cancer
-
Baglietto L, Torrisi R, Arena G, et al. Ocular effects of fenretinide, a vitamin A analog, in a chemoprevention trial of bladder cancer. Cancer Detect Prev 2000;24: 369-75.
-
(2000)
Cancer Detect Prev
, vol.24
, pp. 369-375
-
-
Baglietto, L.1
Torrisi, R.2
Arena, G.3
-
34
-
-
0027078485
-
Effects of meals and meal composition on the bioavailability of fenretinide
-
Doose DR, Minn FL, Stellar S, Nayak RK. Effects of meals and meal composition on the bioavailability of fenretinide. J Clin Pharmacol 1992;32:1089-95.
-
(1992)
J Clin Pharmacol
, vol.32
, pp. 1089-1095
-
-
Doose, D.R.1
Minn, F.L.2
Stellar, S.3
Nayak, R.K.4
-
35
-
-
0033875561
-
N-(4-hydroxyphenyl) retinamide in the chemoprevention of squamous metaplasia and dysplasia of the branchial epithelium
-
Kurie JM, Lee JS, Khuri FR, et al. N-(4-hydroxyphenyl) retinamide in the chemoprevention of squamous metaplasia and dysplasia of the branchial epithelium. Clin Cancer Res 2000;6:2973-9.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2973-2979
-
-
Kurie, J.M.1
Lee, J.S.2
Khuri, F.R.3
-
36
-
-
0033746473
-
Serum retinol, the acute phase response, and the apparent misclassification of vitamin a status in the third National Health and Nutrition Examination Survey
-
Stephensen CB, Gildengorin G. Serum retinol, the acute phase response, and the apparent misclassification of vitamin A status in the third National Health and Nutrition Examination Survey. Am J Clin Nutr 2000;72:1170-8.
-
(2000)
Am J Clin Nutr
, vol.72
, pp. 1170-1178
-
-
Stephensen, C.B.1
Gildengorin, G.2
-
37
-
-
20844453913
-
Randomized trial of fenretinide (4-HPR) to prevent recurrences, new localizations and carcinomas in patients operated on for oral leukoplakia: Long-term results
-
Chiesa F, Tradati N, Grigolato R, et al. Randomized trial of fenretinide (4-HPR) to prevent recurrences, new localizations and carcinomas in patients operated on for oral leukoplakia: long-term results. Int J Cancer 2005;115:625-9.
-
(2005)
Int J Cancer
, vol.115
, pp. 625-629
-
-
Chiesa, F.1
Tradati, N.2
Grigolato, R.3
-
38
-
-
25144502891
-
Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4 HPR at clinically relevant concentrations
-
Sun SY, Schroeder CP, Yue P, Lotan D, Hong WK, Lotan R. Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4 HPR at clinically relevant concentrations. Cancer Biol Ther 2005;4:407-13.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 407-413
-
-
Sun, S.Y.1
Schroeder, C.P.2
Yue, P.3
Lotan, D.4
Hong, W.K.5
Lotan, R.6
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