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Volumn 12, Issue 3, 2006, Pages 247-252

Persistence of neutralizing antibodies after discontunuation of IFNβ therapy in patients with relapsing-remitting multiple sclerosis

Author keywords

IFN therapy; IFN 1a; IFN 1b; Neutralizing antibodies; Relapsing remilling multiple sclerosis

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; GLATIRAMER; IMMUNOGLOBULIN; INTERFERON BETA SERINE; NEUTRALIZING ANTIBODY;

EID: 33744781321     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1191/135248505ms1324oa     Document Type: Article
Times cited : (45)

References (28)
  • 1
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
    • The IFNB Multiple Sclerosis Study Group
    • The IFNB Multiple Sclerosis Study Group. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 1993; 43: 655-61.
    • (1993) Neurology , vol.43 , pp. 655-661
  • 2
    • 0032494792 scopus 로고    scopus 로고
    • Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis
    • European Study Group on interferon beta-1b in secondary progressive MS
    • European Study Group on interferon beta-1b in secondary progressive MS. Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. Lancet 1998; 352: 1491-97.
    • (1998) Lancet , vol.352 , pp. 1491-1497
  • 3
    • 0345601517 scopus 로고    scopus 로고
    • Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
    • PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group
    • PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/ remitting multiple sclerosis. Lancet 1998; 352: 1498-504.
    • (1998) Lancet , vol.352 , pp. 1498-1504
  • 4
    • 0008678962 scopus 로고    scopus 로고
    • Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
    • The Multiple Sclerosis Collaborative Research Group (MSCRG)
    • Jacobs LD, Cookfair DL, Rudick RA, Herndon RM, Richert JR, Salazar AM et al. Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann Neurol 1996; 39: 285-94.
    • (1996) Ann Neurol , vol.39 , pp. 285-294
    • Jacobs, L.D.1    Cookfair, D.L.2    Rudick, R.A.3    Herndon, R.M.4    Richert, J.R.5    Salazar, A.M.6
  • 5
    • 0035849496 scopus 로고    scopus 로고
    • Randomized controlled trial of interferon-beta-1a in secondary progressive MS: Clinical results
    • SPECTRIMS
    • SPECTRIMS. Randomized controlled trial of interferon-beta-1a in secondary progressive MS: clinical results. Neurology 2001; 56: 1496-504.
    • (2001) Neurology , vol.56 , pp. 1496-1504
  • 6
    • 0037180468 scopus 로고    scopus 로고
    • A randomized, double-blind, dose-comparison study of weekly interferon beta-1a in relapsing MS
    • Clanet M, Radue EW, Kappos L, Hartung HP, Hohlfeld R, Sandberg-Wollheim M et al. A randomized, double-blind, dose-comparison study of weekly interferon beta-1a in relapsing MS. Neurology 2002; 59: 1507-17.
    • (2002) Neurology , vol.59 , pp. 1507-1517
    • Clanet, M.1    Radue, E.W.2    Kappos, L.3    Hartung, H.P.4    Hohlfeld, R.5    Sandberg-Wollheim, M.6
  • 7
    • 8844222623 scopus 로고    scopus 로고
    • Interferon beta-1b in secondary progressive MS: Results from a 3-year controlled study
    • Panitch H, Miller A, Paty D, Weinshenker B. Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study. Neurology 2004; 63: 1788-95.
    • (2004) Neurology , vol.63 , pp. 1788-1795
    • Panitch, H.1    Miller, A.2    Paty, D.3    Weinshenker, B.4
  • 8
    • 0037180479 scopus 로고    scopus 로고
    • Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE Trial
    • Panitch H, Goodin DS, Francis G, Chang P, Coyle PK, O'Connor P et al. Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE Trial. Neurology 2002; 59: 1496-506.
    • (2002) Neurology , vol.59 , pp. 1496-1506
    • Panitch, H.1    Goodin, D.S.2    Francis, G.3    Chang, P.4    Coyle, P.K.5    O'Connor, P.6
  • 9
    • 0037181634 scopus 로고    scopus 로고
    • Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: Results of a 2-year prospective randomised multicentre study (INCOMIN)
    • Durelli L, Verdun E, Barbero P, Bergui M, Versino E, Ghezzi A et al. Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomised multicentre study (INCOMIN). Lancet 2002; 359: 1453-60.
    • (2002) Lancet , vol.359 , pp. 1453-1460
    • Durelli, L.1    Verdun, E.2    Barbero, P.3    Bergui, M.4    Versino, E.5    Ghezzi, A.6
  • 10
    • 0005489101 scopus 로고    scopus 로고
    • Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: Experience during the first three years
    • The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
    • The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years. Neurology 1996; 47: 889-94.
    • (1996) Neurology , vol.47 , pp. 889-894
  • 11
    • 0035954361 scopus 로고    scopus 로고
    • PRISMS-4: Long-term efficacy of interferon-beta-1a in relapsing MS
    • PRISMS Study Group
    • PRISMS Study Group. PRISMS-4: Long-term efficacy of interferon-beta-1a in relapsing MS. Neurology 2001; 56: 1628-36.
    • (2001) Neurology , vol.56 , pp. 1628-1636
  • 12
    • 20444490479 scopus 로고    scopus 로고
    • Appearance and disappearance of neutralizing antibodies during interferon-beta therapy
    • Sorensen PS, Koch-Henriksen N, Ross C, Clemmesen KM, Bendtzen K. Appearance and disappearance of neutralizing antibodies during interferon-beta therapy. Neurology 2005; 65: 33-39.
    • (2005) Neurology , vol.65 , pp. 33-39
    • Sorensen, P.S.1    Koch-Henriksen, N.2    Ross, C.3    Clemmesen, K.M.4    Bendtzen, K.5
  • 13
    • 0036329631 scopus 로고    scopus 로고
    • Differential effects of three interferon betas on neutralising antibodies in patients with multiple sclerosis: A follow up study in an independent laboratory
    • Bertolotto A, Malucchi S, Sala A, Orefice G, Carrieri PB, Capobianco M et al. Differential effects of three interferon betas on neutralising antibodies in patients with multiple sclerosis: a follow up study in an independent laboratory. J Neurol Neurosurg Psychiatry 2002; 73: 148-53.
    • (2002) J Neurol Neurosurg Psychiatry , vol.73 , pp. 148-153
    • Bertolotto, A.1    Malucchi, S.2    Sala, A.3    Orefice, G.4    Carrieri, P.B.5    Capobianco, M.6
  • 14
    • 0033763507 scopus 로고    scopus 로고
    • Immunogenicity of interferon-beta in multiple sclerosis patients: Influence of preparation, dosage, dose frequency, and route of administration
    • Danish Multiple Sclerosis Study Group [In Process Citation]
    • Ross C, Clemmesen KM, Svenson M, Sorensen PS, Koch-Henriksen N, Skovgaard GL et al. Immunogenicity of interferon-beta in multiple sclerosis patients: influence of preparation, dosage, dose frequency, and route of administration. Danish Multiple Sclerosis Study Group [In Process Citation]. Ann Neurol 2000; 48: 706-12.
    • (2000) Ann Neurol , vol.48 , pp. 706-712
    • Ross, C.1    Clemmesen, K.M.2    Svenson, M.3    Sorensen, P.S.4    Koch-Henriksen, N.5    Skovgaard, G.L.6
  • 15
    • 0032893144 scopus 로고    scopus 로고
    • The evolution of neutralizing antibodies in multiple sclerosis patients treated with interferon beta-1b
    • Rice GP, Paszner B, Oger J, Lesaux J, Paty D, Ebers G. The evolution of neutralizing antibodies in multiple sclerosis patients treated with interferon beta-1b. Neurology 1999; 52: 1277-79.
    • (1999) Neurology , vol.52 , pp. 1277-1279
    • Rice, G.P.1    Paszner, B.2    Oger, J.3    Lesaux, J.4    Paty, D.5    Ebers, G.6
  • 16
    • 0031978274 scopus 로고    scopus 로고
    • Development of neutralizing antibodies in patients with relapsing-remitting multiple sclerosis treated with IFN-beta1a
    • Antonelli G, Bagnato F, Pozzilli C, Simeoni E, Bastianelli S, Currenti M et al. Development of neutralizing antibodies in patients with relapsing-remitting multiple sclerosis treated with IFN-beta1a. J Interferon Cytokine Res 1998; 18: 345-50.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 345-350
    • Antonelli, G.1    Bagnato, F.2    Pozzilli, C.3    Simeoni, E.4    Bastianelli, S.5    Currenti, M.6
  • 17
    • 0002145306 scopus 로고    scopus 로고
    • Results of an ongoing, open-label, safety-extension study of interferon beta-1a (Avonex) treatment in multiple sclerosis
    • Herndon RM, Jacobs LD, Coats ME, Goodkin DE, Mass MK, Richert JR et al. Results of an ongoing, open-label, safety-extension study of interferon beta-1a (Avonex) treatment in multiple sclerosis. Int J MS Care 1999; 2: 1-6.
    • (1999) Int J MS Care , vol.2 , pp. 1-6
    • Herndon, R.M.1    Jacobs, L.D.2    Coats, M.E.3    Goodkin, D.E.4    Mass, M.K.5    Richert, J.R.6
  • 18
    • 0742304139 scopus 로고    scopus 로고
    • Long-term persisting interferon beta-1b neutralizing antibodies after discontinuation of treatment
    • Reske D, Walser A, Haupt WF, Petereit HF. Long-term persisting interferon beta-1b neutralizing antibodies after discontinuation of treatment. Acta Neurol Scand 2004; 109: 66-70.
    • (2004) Acta Neurol Scand , vol.109 , pp. 66-70
    • Reske, D.1    Walser, A.2    Haupt, W.F.3    Petereit, H.F.4
  • 19
    • 0034081983 scopus 로고    scopus 로고
    • The Danish National Project of interferon-beta treatment in relapsing-remitting multiple sclerosis
    • The Danish Multiple Sclerosis Group
    • Koch-Henriksen N, Sorensen PS. The Danish National Project of interferon-beta treatment in relapsing-remitting multiple sclerosis. The Danish Multiple Sclerosis Group. Mult Scler 2000; 6: 172-75.
    • (2000) Mult Scler , vol.6 , pp. 172-175
    • Koch-Henriksen, N.1    Sorensen, P.S.2
  • 20
    • 0242658889 scopus 로고    scopus 로고
    • Anti-IFN BAb and NAb antibodies: A minireview
    • Bendtzen K. Anti-IFN BAb and NAb antibodies: a minireview. Neurology 2003; 61: S6-S10.
    • (2003) Neurology , vol.61
    • Bendtzen, K.1
  • 21
    • 10744225329 scopus 로고    scopus 로고
    • Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis
    • Sorensen PS, Ross C, Clemmesen KM, Bendtzen K, Frederiksen JL, Jensen K et al. Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis. Lancet 2003; 362: 1184-91.
    • (2003) Lancet , vol.362 , pp. 1184-1191
    • Sorensen, P.S.1    Ross, C.2    Clemmesen, K.M.3    Bendtzen, K.4    Frederiksen, J.L.5    Jensen, K.6
  • 23
    • 0034796419 scopus 로고    scopus 로고
    • The neutralization of interferons by antibody. II. Neutralizing antibody unitage and its relationship to bioassay sensitivity: The tenfold reduction unit
    • Grossberg SE, Kawade Y, Kohase M, Klein JP. The neutralization of interferons by antibody. II. Neutralizing antibody unitage and its relationship to bioassay sensitivity: the tenfold reduction unit. J Interferon Cytokine Res 2001; 21: 743-55.
    • (2001) J Interferon Cytokine Res , vol.21 , pp. 743-755
    • Grossberg, S.E.1    Kawade, Y.2    Kohase, M.3    Klein, J.P.4
  • 24
    • 0034798067 scopus 로고    scopus 로고
    • The neutralization of interferons by antibody. I. Quantitative and theoretical analyses of the neutralization reaction in different bioassay systems
    • Grossberg SE, Kawade Y, Kohase M, Yokoyama H, Finter N. The neutralization of interferons by antibody. I. Quantitative and theoretical analyses of the neutralization reaction in different bioassay systems. J Interferon Cytokine Res 2001; 21: 729-42.
    • (2001) J Interferon Cytokine Res , vol.21 , pp. 729-742
    • Grossberg, S.E.1    Kawade, Y.2    Kohase, M.3    Yokoyama, H.4    Finter, N.5
  • 25
    • 27744509228 scopus 로고    scopus 로고
    • Guidelines on use of anti-interferon-beta antibody measurements in multiple sclerosis-Report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis
    • Sorensen PS, Deisenhammer F, Duda P, Hohlfeld R, Myhr KM, Palace J et al. Guidelines on use of anti-interferon-beta antibody measurements in multiple sclerosis-Report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis. Eur J Neurol 2005; 12: 1-11.
    • (2005) Eur J Neurol , vol.12 , pp. 1-11
    • Sorensen, P.S.1    Deisenhammer, F.2    Duda, P.3    Hohlfeld, R.4    Myhr, K.M.5    Palace, J.6
  • 26
    • 20444490479 scopus 로고    scopus 로고
    • Appearance and disappearance of neutralizing antibodies during interferon-beta therapy
    • Sorensen PS, Koch-Henriksen N, Ross C, Clemmesen KM, Bendtzen K. Appearance and disappearance of neutralizing antibodies during interferon-beta therapy. Neurology 2005; 65: 33-39.
    • (2005) Neurology , vol.65 , pp. 33-39
    • Sorensen, P.S.1    Koch-Henriksen, N.2    Ross, C.3    Clemmesen, K.M.4    Bendtzen, K.5
  • 27
    • 0036158851 scopus 로고    scopus 로고
    • Monthly corticosteroids decrease neutralizing antibodies to IFNbeta1 b: A randomized trial in multiple sclerosis
    • Pozzilli C, Antonini G, Bagnato F, Mainero C, Tomassini V, Onesti E et al. Monthly corticosteroids decrease neutralizing antibodies to IFNbeta1 b: a randomized trial in multiple sclerosis. J Neurol 2002; 249: 50-56.
    • (2002) J Neurol , vol.249 , pp. 50-56
    • Pozzilli, C.1    Antonini, G.2    Bagnato, F.3    Mainero, C.4    Tomassini, V.5    Onesti, E.6
  • 28
    • 0034744952 scopus 로고    scopus 로고
    • Interferon-beta (IFN-beta) antibodies in interferon-beta 1a- and interferon-beta 1b-treated multiple sclerosis patients. Prevalence, kinetics, cross-reactivity, and factors enhancing interferon-beta immunogenicity in vivo
    • Perini P, Facchinetti A, Bulian P, Massaro AR, De Pascalis D, Bertolotto A et al. Interferon-beta (IFN-beta) antibodies in interferon-beta 1a- and interferon-beta 1b-treated multiple sclerosis patients. Prevalence, kinetics, cross-reactivity, and factors enhancing interferon-beta immunogenicity in vivo. Eur Cytokine Netw 2001; 12: 56-61.
    • (2001) Eur Cytokine Netw , vol.12 , pp. 56-61
    • Perini, P.1    Facchinetti, A.2    Bulian, P.3    Massaro, A.R.4    De Pascalis, D.5    Bertolotto, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.