Lignocaine and chlorhexidine toxicity in children resulting from mouth paint ingestion: A bottling problem

Journal of Paediatrics and Child Health

Volumn 42, Issue 6, 2006, Pages 350-353

  Balit, Corrine R ^a   Lynch, Anne Maree ^c   Gilmore, Simon P ^a,b   Murray, Lindsay ^a,d   Isbister, Geoffrey K ^a,e  

^a CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c SCGH   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

Author keywords

Chlorhexidine; Lignocaine; Toxicity

Indexed keywords

CHLORHEXIDINE; LIDOCAINE;

CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DEMOGRAPHY; DRUG INTOXICATION; DRUG PACKAGING; EXPOSURE; FEMALE; FOLLOW UP; FOOD INTAKE; HUMAN; INFANT; INGESTION; MALE; MEDICATION ERROR; PRESCHOOL CHILD; PRIORITY JOURNAL; REVIEW; SALIVATION; SYMPTOM; VOMITING;

ADMINISTRATION, ORAL; ANESTHETICS, LOCAL; CHILD, PRESCHOOL; CHLORHEXIDINE; DRUG LABELING; DRUG PACKAGING; FEMALE; HUMANS; INFANT; LIDOCAINE; MALE; MEDICATION ERRORS; MOUTHWASHES; POISON CONTROL CENTERS; SOUTH AUSTRALIA;

EID: 33744759311     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/j.1440-1754.2006.00871.x     Document Type: Review

References (17)

1. Smith M, Wolfram W, Rose R. Toxicity-seizures in an infant caused by (or related to) oral viscous lidocaine use. J. Emerg. Med. 1992 10: 587 90.
2. Gunter JB. Benefit and risks of local anesthetics in infants and children. Pediatr. Drugs 2002 4: 649 72.
3. Denaro CP, Benowitz NL. Poisoning due to class 1B antiarrhythmic drugs: lignocaine, mexiletine tocainide. Med. Toxicol. Adverse Drug Exp. 1989 4: 412 28.
4. Hess GP, Walson PD. Seizures secondary to oral viscous lidocaine. Ann. Emerg. Med. 1986 17: 725 7.
5. Chiang YY, Tseng KF, Lih YW, Tsai TC, Liu CT, Leung HK. Lidocaine-induced CNS toxicity - a case report. Acta Anaesthesiol. Sin. 1996 34: 243 6.
6. Gonzalez del Rey J, Wason S, Druckenbrod RW. Lidocaine overdose: another preventable case? Pediatr. Emerg. Care 1994 10: 344 6.
7. Chlorhexidine Salts Monograph. Micromedex health care series, version 125. Colorado: Thomson Health Care, 2005.
8. Eisinger AJ, Hellier MD. Oral lignocaine. Lancet 1969 2: 1303.
9. Rothstein P, Dornbusch J, Shaywitz BA. Prolonged seizures associated with the use of viscous lidocaine. J. Pediatr. 1982 101: 461 3.
10. Sakai S, Lattin JE. Lidocaine ingestion. Am. J. Dis. Child. 1980 134: 323.
11. Giard MJ, Uden DL, Whitlock DJ, Watson DM. Seizures induced by oral viscous lidocaine. Clin. Pharm. 1983 2: 110.
12. Garrettson LK, McGee EB. Rapid onset of seizures following aspiration of viscous lidocaine. Clin. Toxicol. 1992 30: 413 22.
13. Amitai Y, Whitesell L, Lovejoy FH Jr. Death following accidental lidocaine overdose in a child. N. Engl. J. Med. 1986 314: 182 3.
14. Mucklow ES. Accidental feeding of a dilute antiseptic solution (Chlorhexidine 0.05% with cetrimide 1%) to five babies. Hum. Toxicol. 1988 7: 567 9.
15. Quinn MW, Bini RM. Bradycardia associated with chlorhexidine spray. Arch. Dis. Child. 1989 64: 892 3.
16. Macknin ML, Piedmonte M, Jacobs J, Skibinski C. Symptoms associated with infant teething: a prospective study. Pediatrics 2000 105 4 Pt 1 747 52.
17. McIntyre GT, McIntrye GM. Teething troubles? Br. Dent. J. 2002 192: 251 5.