A new experimental protocol as an alternative to the colony-forming unit-granulocyte/macrophage (CFU-GM) clonogenic assay to assess the haematotoxic potential of new drugs

Toxicology in Vitro

Volumn 20, Issue 5, 2006, Pages 750-756

  Dal Negro, Gianni ^a   Vandin, Luca ^a   Bonato, Monica ^a   Repeto, Paolo ^a   Sciuscio, Davide ^b  

^a GSK   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Bone marrow; Colony forming unit granulocyte macrophages; Flow cytometry; In vitro; Monoclonal antibodies

Indexed keywords

DOXORUBICIN; MONOCLONAL ANTIBODY; ZIDOVUDINE;

ANIMAL CELL; ARTICLE; BLOOD TOXICITY; BONE MARROW TOXICITY; CELL COUNT; CELL SUBPOPULATION; CLONOGENIC ASSAY; COLONY FORMING UNIT GM; CONTROLLED STUDY; FLOW CYTOMETRY; IN VITRO STUDY; LIQUID CULTURE; MALE; MICROSCOPY; MOUSE; NONHUMAN;

ANIMALS; CELL LINEAGE; COLONY-FORMING UNITS ASSAY; CULTURE MEDIA; DOXORUBICIN; FLOW CYTOMETRY; GRANULOCYTES; HEMATOPOIETIC STEM CELLS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; ZIDOVUDINE;

EID: 33744546475     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.10.015     Document Type: Article

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