Examination of gene fusion status in archival samples of alveolar Rhabdomyosarcoma entered on the Intergroup Rhabdomyosarcoma Study - III trial: A report from the children's oncology group

Journal of Molecular Diagnostics

Volumn 8, Issue 2, 2006, Pages 202-208

  Barr, Frederic G ^a   Smith, Lynette M ^b   Lynch, James C ^b   Strzelecki, Donna ^a   Parham, David M ^c   Qualman, Stephen J ^d   Breitfeld, Philip P ^e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE; PARAFFIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX7;

ARTICLE; CHILD; COHORT ANALYSIS; CONSENSUS SEQUENCE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; FEMALE; GENE FUSION; GENE PROBE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; RHABDOMYOSARCOMA; SENSITIVITY ANALYSIS; TISSUE FIXATION;

EID: 33744523389     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.2353/jmoldx.2006.050124     Document Type: Article

References (10)

1. Barr FG, Ladanyi M: Sarcomas. Diagnostic Molecular Pathology. Edited by Leonard DGB. Philadelphia, Saunders, 2003, pp 53-76
2. Barr FG: Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene 2001, 20:5736-5746
3. Barr FG, Chatten J, D'Cruz CM, Wilson AE, Nauta LE, Nycum LM, Biegel JA, Womer RB: Molecular assays for chromosomal translocations in the diagnosis of pediatric soft tissue sarcomas. JAMA 1995, 273:553-557
4. Sorensen PH, Lynch JC, Qualman SJ, Tirabosco R, Lim JF, Maurer HM, Bridge JA, Crist WM, Triche TJ, Barr FG: PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group. J Clin Oncol 2002, 20:2672-2679
5. Crist W, Gehan EA, Ragab AH, Dickman PS, Donaldson SS, Fryer C, Hammond D, Hays DM, Herrmann J, Heyn R, Jones PM, Lawrence W, Newton W, Ortega J, Raney RB, Ruymann FB, Tefft M, Webber B, Wiener E, Wharam M, Vietti TJ, Maurer HM: The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 1995, 13:610-630
6. Edwards RH, Chatten J, Xiong QB, Barr FG: Detection of gene fusions in rhabdomyosarcoma by reverse transcriptase-polymerase chain reaction assay of archival samples. Diagn Mol Pathol 1997, 6:91-97
7. Horn Jr RC, Enterline HT: Rhabdomyosarcoma: a clinicopathological study and classification of 39 cases. Cancer 1958, 11:181-199
8. Petrie A, Sabin C: Medical Statistics at a Glance. Oxford, Blackwell Science Ltd., 2000
9. Zucman J, Melot T, Desmaze C, Ghysdael J, Plougastel B, Peter M, Zucker JM, Triche TJ, Sheer D, Turc-Carel C, Ambros P, Combaret V, Lenoir G, Aurias A, Thomas G, Delattre O: Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J 1993, 12:4481-4487
10. Newton Jr WA, Gehan EA, Webber BL, Marsden HB, van Unnik AJ, Hamoudi AB, Tsokos MG, Shimada H, Harms D, Schmidt D, Ninfo V, Cavazzana AO, Gonzalez-Crussi F, Parham DM, Reiman HM, Asmar L, Beltangady MS, Sachs NE, Triche TJ, Maurer HM: Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification - an Intergroup Rhabdomyosarcoma Study. Cancer 1995, 76:1073-1085