Sex-, stage- and tissue-specific regulation by a mosquito hexamerin promoter

Insect Molecular Biology

Volumn 15, Issue 3, 2006, Pages 301-311

  Jinwal, U K ^a   Zakharkin, S O ^b   Litvinova, O V ^a   Jain, S ^a   Beneš, Helen ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Doublesex; Fat body; Gel shift assays; Hexamerin gene regulation; Mosquito; Sex specificity

Indexed keywords

DNA BINDING PROTEIN; DOUBLESEX PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; LUCIFERASE; NUCLEAR PROTEIN; TRANSFORMER PROTEIN, DROSOPHILA;

ANIMAL; ARTICLE; DNA FLANKING REGION; DROSOPHILA MELANOGASTER; FAT BODY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIFE CYCLE; MALE; METABOLISM; MUTATION; OCHLEROTATUS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROMOTER REGION; REPORTER GENE; SEXUAL DEVELOPMENT;

5' FLANKING REGION; ANIMALS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FAT BODY; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; LIFE CYCLE STAGES; LUCIFERASES; MALE; MUTATION; NUCLEAR PROTEINS; OCHLEROTATUS; PROMOTER REGIONS (GENETICS); SEX CHARACTERISTICS;

DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; OCHLEROTATUS ATROPALPUS;

EID: 33744514632     PISSN: 09621075     EISSN: 13652583     Source Type: Journal    
DOI: 10.1111/j.1365-2583.2006.00644.x     Document Type: Article

References (46)

1. Abel T. Bhatt R. Maniatis T. 1992 A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. Gen Dev 6 : 466 480.
2. Alphey L. Beard C.B. Billingsley P. Coetzee M. Crisanti A. Curtis C. et al. 2002 Malaria control with genetically manipulated insect vectors. Science 298 : 119 121.
3. An W. Wensink P.C. 1995a Three protein binding sites form an enhancer that regulates sex- and fat body-specific transcription of Drosophila yolk protein genes. EMBO J 14 : 1221 1230.
4. An W. Wensink P.C. 1995b Integrating sex- and tissue-specific regulation within a single Drosophila enhancer. Genes Dev 9 : 256 266.
5. Attardo G.M. Hansen I.A. Raikhel A.S. 2005 Nutritional regulation of vitellogenesis in mosquitoes: implications for anautogeny. Insect Biochem Mol Biol 35 : 661 675.
6. Beneš H. Neal K.C. Willis R.L. Gadde D. Castleberry A.B. Korochkina S.E. 1996 Overlapping Lsp-2 gene sequences target expression to both the larval and adult Drosophila fat body. Insect Mol Biol 5 : 39 49.
7. Burmester T. Massey H.C. Jr. Zakharkin S.O. Beneš H. 1998 The evolution of hexamerins and the phylogeny of insects. J Mol Evol 47 : 93 108.
8. Burtis K.C. Baker B.S. 1989 Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell 56 : 997 1010.
9. Burtis K.C. Coschigano K.T. Baker B.S. Wensink P.C. 1991 The doublesex proteins of Drosophila melanogaster bind directly to a sex-specific yolk protein gene enhancer. EMBO J 10 : 2577 2582.
10. Candy D.J. 1985 Intermediary metabolism. In : Comprehensive Insect Physiology, Biochemistry and Pharmacology Kerkurt G.A Gilbert L.I., eds), Vol. 10, pp. 1 41. Pergamon Press, Oxford.
11. Cho S. Wensink P.C. 1996 Purification and physical properties of the male and female Doublesex proteins of Drosophila. Proc Natl Acad Sci USA 93 : 2043 2047.
12. Cho S. Wensink P.C. 1997 DNA binding by the male and female Doublesex proteins of Drosophila melanogaster. J Biol Chem 272 : 3185 3189.
13. Cline T.W. Meyer B.J. 1996 Vive la difference: males vs females in flies vs worms. Annu Rev Genet 30 : 637 702.
14. Dulac C. 2005 Sex and the single splice. Cell 121 : 664 666.
15. Erdman S.E. Burtis K.C. 1993 The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain. EMBO J 12 : 527 535.
16. Erdman S.E. Chen H.J. Burtis K.C. 1996 Functional and genetic characterization of the oligomerization and DNA binding properties of the Drosophila doublesex proteins. Genetics 144 : 1639 1652.
17. Falb D. Maniatis T. 1992a Drosophila transcriptional repressor protein that binds specifically to negative control elements in fat body enhancers. Mol Cell Biol 12 : 4093 4103.
18. Falb D. Maniatis T. 1992b A conserved regulatory unit implicated in tissue-specific gene expression in Drosophila and man. Genes Dev 6 : 454 465.
19. Garabedian M.J. Shepherd B.M. Wensink P.C. 1986 A tissue-specific transcription enhancer from the Drosophila yolk protein 1 gene. Cell 45 : 859 867.
20. Haunerland N.H. 1996 Insect storage proteins: gene families and receptors. Insect Biochem Mol Biol 26 : 755 765.
21. Haunerland N.H. Shirk P.D. 1995 Regional and functional differentiation in the insect fat body. Annu Rev Entomol 40 : 121 145.
22. Hediger M. Burghardt G. Siegenthaler C. Buser N. Hilfiker-Kleiner D. Dûbendorfer, and Bopp D. 2004 Sex determination in Drosophila melanogaster and Musca domestica converges at the level of the terminal regulator doublesex. Dev Genes Evol 214 : 29 42.
23. Heinrichs V. Ryner L.C. Baker B.S. 1998 Regulation of sex-specific selection of fruitless 5′ splice sites by transformer and transformer-2. Mol Cell Biol 18 : 450 458.
24. Hodgkin J. 2002 The remarkable ubiquity of DM domain factors as regulators of sexual phenotype: ancestry or aptitude. Genes Dev 16 : 2322 2326.
25. Hoshijima K. Inoue K. Higuchi I. Sakamoto H. Shimura Y. 1991 Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila. Science 252 : 833 836.
26. Inoue K. Hoshijima K. Higuchi I. Sakamoto H. Shimura Y. 1992 Binding of the Drosophila transformer and transformer-2 proteins to the regulatory elements of doublesex primary transcript for sex-specific RNA processing. Proc Natl Acad Sci USA 89 : 8092 8096.
27. Kapitskaya M.Z. Dittmer N.T. Deitsch K.W. Cho W.L. Taylor D.G. Leff T. Raikhel A.S. 1998 Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito. J Biol Chem 273 : 29801 29810.
28. Kokoza V. Ahmed A. Cho W.-L. Jasinskiene N. James A.A. Raikhel A. 2000 Engineering blood meal-activated systemic immunity in the yellow fever mosquito, Aedes aegypti. Proc Natl Acad Sci USA 97 : 9144 9149.
29. Kokoza V.A. Martin D. Mienaltowski M.J. Ahmed A. Christina M.M. Raikhel A.S. 2001 Transcriptional regulation of the mosquito vitellogenin gene via a blood meal-triggered cascade. Gene 274 : 47 65.
30. Korochkina S.E. Gordadze A.V. Zakharkin S.O. Beneš H. 1997 Differential accumulation and tissue distribution of mosquito hexamerins during metamorphosis. Insect Biochem Mol Biol 27 : 813 824.
31. Kuhn S. Sievert V. Traut W. 2000 The sex-determining gene doublesex in the fly Megaselia scalaris: conserved structure and sex-specific splicing. Genome 43 : 1011 1020.
32. Livak K.J. Schmittgen T.D. 2001 Analysis of relative gene expression data using real-time quantitative PCR and the method. Methods 25 : 402 408.
33. Martin D. Piulachs M.D. Raikhel A.S. 2001 A novel GATA factor transcriptionally represses yolk protein precursor genes in the mosquito Aedes aegypti via interaction with the CtBP corepressor. Mol Cell Biol 21 : 164 174.
34. Mitsialis S.A. Kafatos F.C. 1985 Regulatory elements controlling chorion gene expression are conserved between flies and moths. Nature 317 : 453 456.
35. Nagoshi R.N. Baker B.S. 1990 Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns. Genes Dev 4 : 89 97.
36. Pirrotta V. 1988 Vectors for P-mediated transformation in Drosophila. Biotechnology 10 : 437 456.
37. Raymond C.S. Shamu C.E. Shen M.M. Seifert K.J. Hirsch B. Hodgkin J. Zarkower D. 1998 Evidence for evolutionary conservation of sex-determining genes. Nature 391 : 691 695.
38. Rubin G.M. Spradling A.C. 1982 Genetic transformation of Drosophila with transposable element vectors. Science 218 : 348 353.
39. Scali C. Catteruccia F. Li Q. Crisanti A. 2005 Identification of sex-specific transcripts of the Anopheles gambiae doublesex gene. J Exp Biol 208 : 3701 3709.
40. Sofer W. Martin P.F. 1987 Analysis of alcohol dehydrogenase gene expression in Drosophila. Annu Rev Genet 21 : 203 205.
41. Suzuki M.G. Funaguma S. Kanda T. Tamura T. Shimada T. 2003 Analysis of the biological functions of a doublesex homologue in Bombyx mori. Dev Genes Evol 213 : 345 354.
42. Tan K.H. 2000 Area-wide Control of Fruit Flies and Other Pests. Pulau Penang. Penerbir Univeriti Sains, Wallingford, UK.
43. Telfer W.H. Kunkel J.G. 1991 The function and evolution of insect storage hexamers. Annu Rev Entomol 36 : 205 228.
44. Zakharkin S.O. Gordadze A.V. Krochkina S.E. Mathiopoulos K.D. della Torre A. Beneš H. 1997 Molecular cloning and expression of an hexamerin gene from the malaria mosquito, Anopheles gambiae. Eur J Biochem 246 : 719 726.
45. Zakharkin S.O. Headley V.V. Kumar N.K. Buck N.A. Wheeler D.E. Beneš H. 2001 Female-specific expression of a hexamerin gene in larvae of an autogenous mosquito. Eur J Biochem 268 : 5713 5722.
46. Zarkower D. 2002 Invertebrates may not be so different after all. Novartis Found Symp 244 : 115 126 Discussion 126-135 203-116 253 117.