Regioselective benzylation of azido-containing monosaccharides

Synlett

Volumn , Issue 8, 2006, Pages 1217-1220

  Fan, Qiu Hua ^a   Li, Qin ^a   Zhang, Li He ^a   Ye, Xin Shan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Alkylation; Azido containing monosaccharides; Hydroxyl group; Protection; Selective benzylation

Indexed keywords

AZIDE; HYDROXYL GROUP; MONOSACCHARIDE;

ALKYLATION; ARTICLE; BENZYLATION; CHEMICAL REACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 33744478646     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-939681     Document Type: Article

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26. The reaction conditions such as solvents, temperature, and ratio of reagents were investigated. The optimized reaction conditions: molar ratio of NaH/BnBr/substrates (1.3:1.3:1), DMF as solvent, reaction temperature (-15 °C to r.t.).
27. 3S: C, 62.77; H, 5.46; N, 16.27. Found: C, 62.70; H, 5.40; N, 16.25.