In vitro effects on proliferation, apoptosis and colony inhibition in ER-dependent and ER-independent human breast cancer cells by selected mushroom species

Oncology Reports

Volumn 15, Issue 2, 2006, Pages 417-423

  Gu, Yu Huan ^a   Leonard, Jessica ^a  

^a BASTYR UNIVERSITY   (United States)

Author keywords

Coprinellus sp.; Coprinus comatus; Estrogen receptor positive and negative; Flammulina velutipes; Human breast cancer; Rapid apoptosis

Indexed keywords

ESTROGEN RECEPTOR; PLANT EXTRACT;

AGARICALES; APOPTOSIS; ARTICLE; BREAST TUMOR; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HUMAN; IN VITRO STUDY; METABOLISM; NICK END LABELING; PHYTOTHERAPY; TUMOR CELL LINE;

AGARICALES; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IN SITU NICK-END LABELING; PHYTOTHERAPY; PLANT EXTRACTS; RECEPTORS, ESTROGEN;

EID: 33744470919     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.15.2.417     Document Type: Article

References (28)

1. Ikekawa T, Uehara N, Maeda Y, Nankinishi M and Fukoka F: Antitumor activity of aqueous extracts of edible mushrooms. Cancer Res 29: 734-735, 1969.
2. Borchers AT, Stern JS and Hackman RM: Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med 221: 281-293, 1999. (Pubitemid 29386016)
3. Ikekawa T: Beneficial effects of edible and medicinal mushrooms on health care. Int J Med Mushrooms 3: 291-298, 2001.
4. Hawksworth DL: Mushrooms: the extent of the unexplored potential. Int J Med Mushrooms 3: 333-340, 2001.
5. Kidd PM: The use of mushroom glucans and proteoglycans in cancer treatment. Altern Med Rev 5: 4-27, 2000.
6. Lam YW, Ng TB and Wang HX: Antiproliferative and antimitogenic activities in a peptide from puffball mushroom Calvatia caelata. Biochem Biophys Res Commun 289: 744-749, 2001. (Pubitemid 33152296)
7. Hsieh TC and Wu JM: Cell growth and gene modulatory activities of Yunzhi (Windsor Wunxi) from mushroom Trametes versicolor in androgen-dependent and androgen-insensitive human prostate cancer cells. Int J Oncol 18: 81-88, 2001.
8. Jiang J, Slivova V, Valachovicova T, Harvey K and Sliva D: Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3. Int J Oncol 24: 1093-1099, 2004.
9. Gu YH and Belury M: Selective induction of apoptosis in murine skin carcinoma cells (CH72) by an ethanol extract of Lentinula edodes. Cancer Lett 220: 21-28, 2005.
10. Sliva D, Labarrere C, Slivova V, Sedlak M, Loyd FP and Ho NWY: Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells. Biochem Biophys Res Commun 298: 602-612, 2002.
11. Grube BJ, Eng ET, Kao YC, Kwon A and Chen S: White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation. J Nutr 131: 3288-3293, 2001. (Pubitemid 33136151)
12. Chen S, Zhou D, Okubo T, Kao Y, Eng E, Grube B, Kwon A, Yang C and Yu B: Prevention and treatment of breast cancer by suppression aromatase activity and expression. Ann NY Acad Sci 963: 229-238, 2002. (Pubitemid 34721716)
13. Toi M, Hattori T and Akagi M: Randomized adjuvant trial to evaluate the addition of tamoxifan and PSK to chemotherapy in patients with primary breast cancer. Cancer 70: 2475-2483, 1992.
14. Morimoto T, Ogawa M and Orita K: Postoperative adjuvant randomized trial comparing chemo-endocrine therapy, chemotherapy and immunotherapy for patients with stage II breast cancer: 5-year results from the Nishinihon cooperative study group of adjuvant chemo-endocrine therapy for breast cancer of Japan. Eur J Cancer 32A: 235-242, 1996.
15. Vermes I, Haanen C, Steffens-Nakken H and Reutelingsperger C: A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Annexin V. J Immunol Methods 184: 39-51, 1995.
16. Gavrieli Y, Sherman Y and Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119: 493-501, 1992.
17. Nomura Y, Tashiro H and Hisamatsu K: Differential effects of estrogen and antiestrogen on in vitro clonogenic growth of human breast cancers in soft agar. J Natl Cancer Inst 82: 1146-1149, 1990. (Pubitemid 20213256)
18. Dorssers LC, van der Flier S, Brinkman A, van Agthoven T, Veldscholte J, Berns EM, Klijn JG, Beex LV and Foekens JA: Tamoxifen resistance in breast cancer: elucidating mechanisms. Drugs 61: 1721-1733, 2001. (Pubitemid 32980504)
19. Wasser SP and Weis AL: Therapeutic effects of substances occurring in higher basidiomycetes mushrooms: a modern perspective (review). Crit Rev Immunol 19: 65-96, 1999. (Pubitemid 29062102)
20. Jong SC and Donovick R: Antitumor and antiviral substances from fungi. Adv Appl Microbiol 34: 183-261, 1989.
21. Otagiri K, Ohkuma T, Ikekawa T and Tanaka S: Intensification of antitumor-immunity by protein-bound polysaccharide, EA6, derived from Flammulina velutipes (Curt. ex Fr.) Sing. Combined with murine leukemia L1210 vaccine in animal experiments. J Pharmacobiodyn 6: 96-104, 1983. (Pubitemid 13107945)
22. Ikekawa T, Yoshioka Y, Emori M, Sano T and Fukuoka F: Studies on the antitumor activity of polysaccharides from Flammulina velutipes (Curt. ex Fr.) Sing. Cancer Chemother Rep 57: 85-86, 1973.
23. Ikekawa T, Ikeda Y, Yoshioka Y, Nakanishi K, Yokoyama E and Yamazaki E: Studies on antitumor polysaccharide, EA3 isolated from a Japanese edible mushroom, Flammulina velutipes (Curt. ex Fr.) Sing. II. The structure of EA3 and further purification of EA5. J Pharmacobiodyn 5: 576-581, 1982. (Pubitemid 13197792)
24. Ikekawa T, Maruyama H, Miyano T, Okura A, Sawasaki Y, Naito K, Kawamura K and Shiratori K: Proflamin, a new antitumor agent: preparation, physicochemical properties and antitumor activity. Jpn J Cancer Res 76: 142-148, 1985. (Pubitemid 15098504)
25. Fujimiya Y, Suzuki Y, Oshiman K, Kobori H, Moriguchi K, Nakashima H, Matumoto Y, Takahara S, Ebina T and Katakura R: Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis. Cancer Immunol Immunother 43: 147-159, 1998. (Pubitemid 28239880)
26. Fullerton SA, Samadi AA, Tortorelis DG, Choudhury MS, Mallouh C, Tazaki H and Konno S: Induction of apoptosis in human prostatic cancer cells with beta-glucan (Maitake mushroom polysaccharide). Mol Urol 4: 7-13, 2000. (Pubitemid 30238683)
27. Finkelstein MP, Aynehchi S, Samadi AA, Drinis S, Choudhury MS, Tazaki H and Konno S: Chemosensitization of carmustine with maitake beta-glucan on androgen-independent prostate cancer cells: involvement of glyoxalase I. J Altern Complem Med 8: 573-580, 2002.
28. De Vere WRW, Hackman RM, Soares SE, Beckett LA and Sun B: Effects of a mushroom mycelium extract on the treatment of prostate cancer. Urology 60: 640-644, 2002. (Pubitemid 35246450) Medicine, National Institutes of Health