A marginal zone phenotype in follicular lymphoma with t(14;18) is associated with secondary cytogenetic aberrations typical of marginal zone lymphoma

Journal of Pathology

Volumn 209, Issue 2, 2006, Pages 258-264

  Torlakovic, E E ^a,b   Aamot, H V ^b   Heim, S ^b,c  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Cytogenetics; Follicular lymphoma; Marginal zone phenotype; Recurrent aberrations

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CHROMOSOME 12; CHROMOSOME 18; CHROMOSOME 1P; CHROMOSOME 1Q; CHROMOSOME 21; CHROMOSOME 22; CHROMOSOME 3; CHROMOSOME 3Q; CHROMOSOME 7P; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION 1; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 14; CHROMOSOME TRANSLOCATION 18; CHROMOSOME TRANSLOCATION 3; CHROMOSOME TRANSLOCATION 6; CONTROLLED STUDY; CYTOGENETICS; FISHER EXACT TEST; FOLLICULAR LYMPHOMA; GENE DELETION; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; TRISOMY; X CHROMOSOME;

CELL DIFFERENTIATION; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 7; CYTOGENETIC ANALYSIS; HUMANS; IMMUNOPHENOTYPING; LYMPHOMA, FOLLICULAR; PHENOTYPE; TRANSLOCATION, GENETIC; TRISOMY;

EID: 33744470350     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.1981     Document Type: Article

References (42)

1. Yunis JJ, Oken MM, Kaplan ME, Ensrud KM, Howe RR, Theologides A. Distinctive chromosomal abnormalities in histologic subtypes of non-Hodgkin's lymphoma. N Engl J Med 1982;307:1231-1236.
2. Tsujimoto Y, Finger LR, Yunis J, Nowell PC, Croce CM. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 1984;226:1097-1099.
3. Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985;228:1440-1443.
4. Bakhshi A, Jensen JP, Goldman P, Wright JJ, McBride OW, Epstein AL, et al. Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 1985;41:899-906.
5. Johansson B, Mertens F, Mitelman F. Cytogenetic evolution patterns in non-Hodgkin's lymphoma. Blood 1995;86:3905-3914.
6. Aamot H, Micci F, Holte H, Delabie J, Heim S. M-FISH cytogenetic analysis of non-Hodgkin lymphomas with t(14;18)(q32;q21) and add(1)(p36) as a secondary abnormality shows that the extra material often comes from chromosome arm l7q. Leuk Lymphoma 2002;43:1051-1056.
7. Streubel B, Simonitsch-Klupp I, Mullauer L, Lamprecht A, Huber D, Siebert R, et al. Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites. Leukemia 2004;18:1722-1726.
8. Dierlamm J, Baens M, Wlodarska I, Stefanova-Ouzounova M, Hernandez JM, Hossfeld DK, et al. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q2l;q2l)p6ssociated with mucosa-associated lymphoid, tissue lymphomas. Blood 1999;93:3601-3609.
9. Auer IA, Gascoyne RD, Connors JM, Cotter FE, Greiner TC, Sanger WG, et al. t(11;18)(q21;q21) is the most common translocation in MALT lymphomas. Ann Oncol 1997;8:979-985.
10. Du MQ, Isaacson PG. Gastric MALT lymphoma: from aetiology to treatment. Lancet Oncol 2002;3:97-104.
11. Streubel B, Lamprecht A, Dierlamm J, Cerroni L, Stolte M, Ott G, et al. T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma. Blood 2003;101:2335-2339.
12. Sonoki T, Harder L, Horsman DE, Karran L, Taniguchi I, Willis TG, et al. Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies. Blood 2001;98:2837-44.
13. Sole F, Espinet B, Salido M, Lloveras E, Fernandez C, Cigudosa JC, et al. Translocation t(6;14)(p12;q32): a novel cytogenetic abnormality in splenic lymphoma with villous lymphocytes. Br J Haematol 2000;110:241-243.
14. Streubel B, Vinatzer U, Lamprecht A, Raderer M, Chott A. T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma. Leukemia 2005;19:652-658.
15. Wotherspoon AC, Finn TM, Isaacson PG. Trisomy 3 in low-grade B-cell lymphomas of mucosa-associated lymphoid tissue. Blood 1995;85:2000-2004.
16. Auer IA, Gascoyne RD, Connors JM, Cotter FE, Greiner TC, Sanger WG, et al. t(11;18)(q21;q21) is the most common translocation in MALT lymphomas. Ann Oncol 1997;8:979-985.
17. Ott G, Kalla J, Steinhoff A, Rosenwald A, Katzenberger T, Roblick U, et al. Trisomy 3 is not a common feature in malignant lymphomas of mucosa-associated lymphoid tissue type. Am J Pathol 1998;153:689-694.
18. Hoeve MA, Gisbertz IA, Schouten HC, Schuuring E, Bot FJ, Hermans J, et al. Gastric low-grade MALT lymphoma, high-grade MALT lymphoma and diffuse large B cell lymphoma show different frequencies of trisomy. Leukemia 1999;13:799-807.
19. Brynes RK, Almaguer PD, Leathery KE, McCourty A, Arber DA, Medeiros LJ, et al. Numerical cytogenetic abnormalities of chromosomes 3, 7, and 12 in marginal zone B-cell lymphomas. Mod Pathol 1996;9:995-1000.
20. Sole F, Woessner S, Florensa L, Espinet B, Mollejo M, Martin P, et al. Frequent involvement of chromosomes 1, 3, 7 and 8 in splenic marginal zone B-cell lymphoma. Br J Haematol 1997;98:446-449.
21. Mateo M, Mollejo M, Villuendas R, Algara P, Sanchez-Beato M, Martinez P, et al. 7q31-32 allelic loss is a frequent finding in splenic marginal zone lymphoma. Am J Pathol 1999;154:1583-1589.
22. Sole F, Salido M, Espinet B, Garcia JL, Martinez Climent JA, Granada I, et al. Splenic marginal zone B-cell lymphomas: two cytogenetic subtypes, one with gain of 3q and the other with loss of 7q. Haematologica 2001;86:71-77.
23. Schmid U, Cogliatti SB, Diss TC, Isaacson PG. Monocytoid/marginal zone B-cell differentiation in follicle centre cell lymphoma. Histopathology 1996;29:201-208.
24. Mollejo M, Menarguez J, Cristobal E, Algara P, Sanchez-Diaz E, Fraga M, et al. Monocytoid B cells. A comparative clinical pathological study of their distribution in different types of low-grade lymphomas. Am J Surg Pathol 1994;18:1131-1139.
25. Yegappan S, Schnitzer B, Hsi ED. FL with marginal zone differentiation: microdissection demonstrates the t(14;18) in both the follicular and marginal zone components. Mod Pathol 2001;14:191-196.
26. Goodlad JR, Batstone PJ, Hamilton D, Hollowood K. Follicular lymphoma with marginal zone differentiation: cytogenetic findings in support of a high-risk variant of follicular lymphoma. Histopathology 2003;42:292-298.
27. Jaffe ES, Harris NL, Stein H, Vardiman JW (eds). Pathology and Genetics of Tumors of Hematopoietic and Lymphoid Tissues. IARC Press: Lyons, France, 2001; 162-167.
28. Mann R, Berard CW. Criteria for the cytologic subclassification of FLs: a proposed alternative method. Hematol Oncol 1983;1:187-192.
29. Isaacson PG, Spencer J. Malignant lymphoma of mucosa-associated lymphoid tissue. Histopathology 1987;11:445-462.
30. Nathwani BN, Anderson JR, Armitage JO, Cavalli F, Diebold J, Drachenberg MR, et al. Clinical significance of follicular lymphoma with monocytoid B cells. Non-Hodgkin's Lymphoma Classification Project. Hum Pathol 1999;30:263-268.
31. Mitelman F (ed). ISCN: An International System for Human Cytogenetic Nomenclature. S. Karger: Basel, 1995.
32. Slovak ML, Weiss LM, Nathwani BN, Bernstein L, Levine AM. Cytogenetic studies of composite lymphomas: monocytoid B-cell lymphoma and other B-cell non-Hodgkin's lymphomas. Hum Pathol 1993;24:1086-1094.
33. Coupland SE, Hellmich M, Auw-Haedrich C, Lee WR, Anagnostopoulos I, Stein H. Plasmacellular differentiation in extranodal marginal zone B cell lymphomas of the ocular adnexa: an analysis of the neoplastic plasma cell phenotype and its prognostic significance in 136 cases. Br J Ophthalmol 2005;89:352-359.
34. Berger F, Traverse-Glehen A, Felman P, Callet-Bauchu E, Baseggio L, Gazzo S, et al. Clinicopathologic features of Waldenstrom's macroglobulinemia and marginal zone lymphoma: are they distinct or the same entity? Clin Lymphoma 2005;5:220-224.
35. Isaacson PG. B cell lymphomas of mucosa associated lymphoid-tumor (MALT) Bull Cancer 1991;78:203-205.
36. Wrong KF, So CC, Chan JC, Kho BC, Chan JK. Gain of chromosome 3/3q in B-cell chronic lymphoproliferative disorder is associated with plasmacytoid differentiation with or without IgM overproduction. Cancer Genet Cytogenet 2002;136:82-85.
37. Corcoran MM, Mould SJ, Orchard JA, Ibbotson RE, Chapman RM, Boright AP, et al. Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chronosome 7q translocations. Oncogene 1999;18:6271-6277.
38. Viaggi S, Abbondandolo A, Carbone M, Ottaggio L, Sessarego M, Zupo S, et al. Uncommon cytogenetic findings in a case of splenic marginal zone lymphoma with aggressive clinical course. Cancer Genet Cytogenet 2004;148:133-136.
39. Cook JR, Sherer ME, Shekhler-Levin S, Swerdlow SH. Nodal marginal zone B-cell lymphoma with a novel t(X;5)(q28;q22): conventional and molecular cytogenetic analysis, Cancer Genet Cytogenet 2003;143:154-159.
40. Harigae H, Ichinohasama R, Miura I, Kameoka J, Meguro K, Miyamura K, et al. Primary marginal zone lymphoma of the thymus accompanied by chromosomal anomaly 46,X, dup(X)(p11p22). Cancer Genet Cytogenet 2002;133:142-147.
41. Boonstra R, Bosga-Bouwer A, van Imhoff GW, Krause V, Palmer M, Coupland RW, et al. Spenic marginal zone lymphomas presenting with slplenomegaly and typical immunophenotype are characterized by allelic loss in 7q31-32. Mod Pathol 2003;16:1210-1217.
42. Streubel B, Lamprecht A, Dierlamm J, Cerroni L, Stolte M, Ott G, et al. T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma. Blood 2003;101:2335-2339.