Soluble adhesion molecules in young children with signs of β-cell autoimmunity - Prospective follow-up from birth

Diabetes/Metabolism Research and Reviews

Volumn 22, Issue 3, 2006, Pages 176-183

  Toivonen, Anna M ^a,b   Kimpimäki, Teija ^a,b   Kupila, Antti ^a,c   Korhonen, Sari ^a,d   Hyöty, Heikki ^a,b   Virtanen, Suvi M ^a,e,f   Ilonen, Jorma ^a,c   Simell, Olli ^a,c   Knip, Mikael ^a,b,g  

^a Juvenile Diabetes Research Foundation International   (United States)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d UNIVERSITY OF OULU   (Finland)

^e UNIVERSITY OF TAMPERE   (Finland)

^f NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^g UNIVERSITY OF HELSINKI   (Finland)

Author keywords

ICAM 1; L selectin; Prediction; Prospective; Type 1 diabetes; Young children

Indexed keywords

AUTOANTIBODY; HLA ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN;

ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELL DAMAGE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE PREDISPOSITION; ENTEROVIRUS; ENTEROVIRUS INFECTION; ENVIRONMENTAL FACTOR; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; PANCREAS ISLET BETA CELL; PATHOGENESIS; PATIENT SELECTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SEROCONVERSION;

AUTOANTIBODIES; AUTOIMMUNITY; DIABETES MELLITUS, TYPE 1; DISEASE SUSCEPTIBILITY; ENTEROVIRUS INFECTIONS; FETAL BLOOD; FOLLOW-UP STUDIES; GENOTYPE; HLA ANTIGENS; HUMANS; INFANT; INFANT, NEWBORN; INTERCELLULAR ADHESION MOLECULE-1; ISLETS OF LANGERHANS; L-SELECTIN; RISK FACTORS;

EID: 33744469849     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.597     Document Type: Article

References (33)

1. Tuomilehto J, Karvonen M, Pitkäniemi J, et al. Record-high incidence of type 1 (insulin-dependent) diabetes mellitus in Finnish children. Diabetologia 1999; 42: 655-660.
2. Rosenbauer J, Herzig P, von Kries R, Neu A, Giani G. Temporal, seasonal, and geographical incidence patterns of type 1 diabetes mellitus in children under 5 years of age in Germany. Diabetologia 1999; 42: 1055-1059.
3. Springer TA. Adhesion receptors of the immune system. Nature 1990; 346: 425-434.
4. von Andrian UH, Mackay CR. T-cell function and migration. Two sides of the same coin. N Engl J Med 2000; 343: 1020-1034.
5. Boyd AW, Wawryk SO, Burns GF, Fecondo JV. Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell-cell contact-mediated immune mechanisms. Proc Natl Acad Sci U S A 1988; 85: 3095-3099.
6. Roep BO, Heidenthal E, de Vries RR, Kolb H, Martin S. Soluble forms of intercellular adhesion molecule-1 in insulin-dependent diabetes mellitus. Lancet 1994; 343: 1590-1593.
7. Martin S, Heidenthal E, Schulte B, Rothe H, Kolb H. Soluble forms of intercellular adhesion molecule-1 inhibit insulitis and onset of autoimmune diabetes. Diabetologia 1998; 41: 1298-1303.
8. Hamann A, Jablonski-Westrich D, Jonas P, Thiele HG. Homing receptors re-examined: mouse LECAM-1 (MEL-14 antigen) is involved in lymphocyte migration into gut-associated lymphoid tissue. Eur J Immunol 1991; 21: 2925-2929.
9. Lampeter ER, Kishimoto TK, Rothlein R, et al. Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM. Diabetes 1992; 41: 1668-1671.
10. Myśliwiec J, Krȩtowski A, Kinalski M, Kinalska I. CD11a expression and soluble ICAM-1 levels in peripheral blood in high-risk and overt type 1 diabetes subjects. Immunol Lett 1999; 70: 69-72.
11. Krȩtowski A, Gillespie KM, Bingley PJ, Kinalska I. Soluble L-selectin levels in type 1 diabetes mellitus: a surrogate marker for disease activity? Immunology 2000; 99: 320-325.
12. Toivonen A, Kulmala P, Savola K, Åkerblom HK, Knip M, The Childhood Diabetes in Finland Study Group. Soluble adhesion molecules in preclinical type 1 diabetes. Pediatr Res 2001; 49: 24-29.
13. Toivonen AM, Kulmala P, Savola K, Åkerblom HK, Knip M, The Childhood Diabetes in Finland Study Group. Soluble adhesion molecules in preclinical type 1 diabetes: a prospective study. Diabetologia 2003; 46: 492-495.
14. Gearing AJ, Newman W. Circulating adhesion molecules in disease. Immunol Today 1993; 14: 506-512.
15. Kupila A, Muona P, Simell T, et al. Feasibility of genetic and immunological prediction of type 1 diabetes in a population-based birth cohort. Diabetologia 2001; 44: 290-297.
16. Kimpimäki T, Kupila A, Hämäläinen A-M, et al.. The first signs of β-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study. J Clin Endocrinol Metab 2001; 86: 4782-4788.
17. Sjöroos M, Iitiä A, Ilonen J, Reijonen H, Lövgren T. Triple-label hybridization assay for type-1 diabetes-related HLA alleles. Biotechniques 1995; 18: 870-877.
18. Lernmark AA, Molenaar JL, van Beers WAM, et al. The Fourth international serum exchange workshop to standardize cytoplasmic islet cell antibodies. Diabetologia 1991; 34: 534-535.
19. Ronkainen M, Hämäläinen A-M, Koskela P, Åkerblom HK, Knip M, The Finnish TRIGR Study Group. Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord blood serum. Clin Exp Immunol 2001; 124: 190-196.
20. Williams AJK, Bingley PJ, Bonifacio E, Palmer JP, Gale EAM. A novel micro-assay for insulin autoantibodies. J Autoimmun 1997; 10: 473-478.
21. Savola K, Sabbah E, Kulmala P, et al. Autoantibodies associated with type 1 diabetes mellitus persist after diagnosis in children. Diabetologia 1998; 41: 1293-1297.
22. Savola K, Bonifacio E, Sabbah E, et al. 1998 IA-2 antibodies - a sensitive marker of IDDM with clinical onset in childhood and adolescence. Diabetologia 1998; 41: 424-429.
23. Lönnrot M, Korpela K, Knip M, et al. Enterovirus infection as a risk factor for β-cell autoimmunity in a prospectively observed birth cohort: the Finnish Diabetes Prediction and Prevention Study. Diabetes 2000; 49: 1314-1318.
24. Lönnrot M, Sjöroos M, Salminen K, et al. Diagnosis of entero-and rhinovirus infections by RT-PCR and time-resolved fluorometry with lanthanide chelate labeled probes. J Med Virol 1999; 59: 378-384.
25. Matthews JNS, Altman DG, Campbell MJ, Royston P. Analysis of serial measurement in medical research. BMJ 1990; 300: 230-235.
26. Schleiffenbaum B, Spertini O, Tedder TF. Soluble L-selectin is present in human plasma at high levels and retains functional activity. J Cell Biol 1992; 119: 229-238.
27. Toivonen A, Kulmala P, Rahko P, Ilonen J, Knip M. Soluble adhesion molecules in Finnish school children with signs of preclinical type 1 diabetes. Diabetes Metab Res Rev 2004; 20: 48-54.
28. Foulis AK, Liddle CN, Farquharson MA, Richmond JA, Weir RS. The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom. Diabetologia 1986; 29: 267-274.
29. Racaniello VR. Early events in infection: receptor binding and cell entry. In Human Enterovirus Infections, Rothbart HA (ed). American Society for Microbiology: Washington, DC, 1995; 73-93.
30. Smyth RL, Fletcher JN, Thomas HM, Hart CA. Immunological responses to respiratory syncytial virus infection in infancy. Arch Dis Child 1997; 76: 210-214.
31. van Kempen M, Bachert C, van Cauwenberge P. An update on the pathophysiology of rhinovirus upper respiratory tract infections. Rhinology 1999; 37: 97-103.
32. Kulander L, Pauksens K, Venge P. Soluble adhesion molecules, cytokines and cellular markers in serum in patients with acute infections. Scand J Infect Dis 2001; 33: 290-300.
33. Hyöty H, Hiltunen M, Knip M, et al. A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Diabetes 1995; 44: 652-657.