Increased expression of lipoxygenase enzymes during pollen season in nasal biopsies of pollen-allergic patients

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 61, Issue 6, 2006, Pages 725-730

  Plewako, H ^a   Holmberg, K ^a   Oancea, I ^a   Rak, S ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cyclo oxygenase pathway; Eicosanoids; Lipo oxygenase pathway; Seasonal rhinitis

Indexed keywords

ACRIVASTINE; ANTASTEN PRIVIN; ANTAZOLINE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CROMOGLYCATE DISODIUM; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GRASS POLLEN EXTRACT; ICOSANOID; LEUKOTRIENE A4 HYDROLASE; LEVOCABASTINE; LIPOXYGENASE; POLLEN ANTIGEN; PROSTAGLANDIN SYNTHASE; XYLOMETAZOLINE;

ADULT; ARTICLE; BIRCH; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; HAY FEVER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; ICOSANOID METABOLISM; MALE; MAST CELL; NASAL BIOPSY; NEUTROPHIL; POLLEN ALLERGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHINOCONJUNCTIVITIS; SCORING SYSTEM; SEASONAL VARIATION; SYMPTOM; T LYMPHOCYTE; TISSUE SECTION;

ADULT; ALLERGENS; BIOPSY; CARRIER PROTEINS; EOSINOPHILS; EPOXIDE HYDROLASES; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOHISTOCHEMISTRY; LIPOXYGENASE; MALE; MAST CELLS; MEMBRANE PROTEINS; MIDDLE AGED; NASAL MUCOSA; POLLEN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RHINITIS, ALLERGIC, SEASONAL;

EID: 33744468255     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2006.00980.x     Document Type: Article

References (29)

1. Broide DH. Molecular and cellular mechanisms of allergic disease. J Allergy Clin Immunol 2001 108 Suppl. 2 S65 71.
2. Howarth PH. Mediators of nasal blockage in allergic rhinitis. Allergy 1997 52 Suppl. 40 12 18.
3. Creticos PS Peters SP Adkinson NF Jr. Naclerio RM Hayes EC Norman PS et al. Peptide leukotriene release after antigen challenge in patients sensitive to ragweed. N Engl J Med 1984 310 : 1626 1630.
4. Miadonna A Milazzo N Gibelli S Salmaso C Lorini M Tedeschi A. Nasal response to a single antigen challenge in patients with allergic rhinitis - inflammatory cell recruitment persists up to 48 hours. Clin Exp Allergy 1999 29 : 941 949.
5. Volovitz B Osur SL Bernstein JM Ogra PL. Leukotriene C4 release in upper respiratory mucosa during natural exposure to ragweed-sensitive children. J Allergy Clin Immunol 1988 82 : 414 418.
6. Smith WL Garavito RM DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 1996 271 : 33157 33160.
7. Dixon RA Diehl RE Opas E Rands E Vickers PJ Evans JF et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990 343 : 282 284.
8. Haeggstrom JZ. Structure, function, and regulation of leukotriene A4 hydrolase. Am J Respir Crit Care Med 2000 161 2 Pt 2 S25 31.
9. Christmas P Weber BM McKee M Brown D Soberman RJ. Membrane localization and topology of leukotriene C4 synthase. J Biol Chem 2002 277 : 28902 28908 (Epub 2002, 21 May).
10. Maltby NH Taylor GW Ritter JM Moore K Fuller RW Dollery CT. Leukotriene C4 elimination and metabolism in man. J Allergy Clin Immunol 1990 85 1 Pt 1 3 9.
11. Higashi N Taniguchi M Mita H Ishii T Akiyama K. Nasal blockage and urinary leukotriene E4 concentration in patients with seasonal allergic rhinitis. Allergy 2003 58 : 476 480.
12. Dahlen B Dahlen SE. Leukotrienes as mediators of airway obstruction and inflammation in asthma. Clin Exp Allergy 1995 25 Suppl. 2 50 54.
13. Seymour ML Rak S Aberg D Riise GC Penrose JF Kanaoka Y et al. Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics. Am J Respir Crit Care Med 2001 164 : 2051 2056.
14. Johansson SG Hourihane JO Bousquet J Bruijnzeel-Koomen C Dreborg S Haahtela T et al. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy 2001 56 : 813 824.
15. Fokkens WJ Godthelp T Holm AF Blom H Mulder PG Vroom TM et al. Dynamics of mast cells in the nasal mucosa of patients with allergic rhinitis and non-allergic controls: a biopsy study. Clin Exp Allergy 1992 22 : 701 710.
16. Calderon MA Lozewicz S Prior A Jordan S Trigg CJ Davies RJ. Lymphocyte infiltration and thickness of the nasal mucous membrane in perennial and seasonal allergic rhinitis. J Allergy Clin Immunol 1994 93 : 635 643.
17. Ciprandi G Buscaglia S Pesce G Pronzato C Ricca V Parmiani S et al. Minimal persistent inflammation is present at mucosal level in patients with asymptomatic rhinitis and mite allergy. J Allergy Clin Immunol 1995 96 6 Pt 1 971 979.
18. Bandeira-Melo C Bozza PT Weller PF. The cellular biology of eosinophil eicosanoid formation and function. J Allergy Clin Immunol 2002 109 : 393 400.
19. Cai Y Bjermer L Halstensen TS. Bronchial mast cells are the dominating LTC4S-expressing cells in aspirin-tolerant asthma. Am J Respir Cell Mol Biol 2003 29 : 683 693 (Epub 2003, 19 June).
20. Williams JD Czop JK Austen KF. Release of leukotrienes by human monocytes on stimulation of their phagocytic receptor for particulate activators. J Immunol 1984 132 : 3034 3040.
21. Shaw RJ Cromwell O Kay AB. Preferential generation of leukotriene C4 by human eosinophils. Clin Exp Immunol 1984 56 : 716 722.
22. Hakansson L Westerlund D Venge P. New method for the measurement of eosinophil migration. J Leukoc Biol 1987 42 : 689 696.
23. Diamant Z Hiltermann JT van Rensen EL Callenbach PM Veselic-Charvat M van der Veen H et al. The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma. Am J Respir Crit Care Med 1997 155 : 1247 1253.
24. Laitinen LA Laitinen A Haahtela T Vilkka V Spur BW Lee TH. Leukotriene E4 and granulocytic infiltration into asthmatic airways. Lancet 1993 341 : 989 990.
25. Figueroa DJ Borish L Baramki D Philip G Austin CP Evans JF. Expression of cysteinyl leukotriene synthetic and signalling proteins in inflammatory cells in active seasonal allergic rhinitis. Clin Exp Allergy 2003 33 : 1380 1388.
26. Coffey MJ Wilcoxen SE Peters-Golden M. Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages. Am J Respir Cell Mol Biol 1994 11 : 153 158.
27. Sugimoto M Sugiyama S Yanagita N Ozawa T. Laser high performance liquid chromatography determination of prostaglandins in nasal lavage fluid in allergic rhinitis. Clin Exp Allergy 1994 24 : 324 329.
28. Demoly P Crampette L Lebel B Campbell AM Mondain M Bousquet J. Expression of cyclo-oxygenase 1 and 2 proteins in upper respiratory mucosa. Clin Exp Allergy 1998 28 : 278 283.
29. Church MK Griffiths TJ Jeffery S Ravell LC Cowburn AS Sampson AP et al. Are cysteinyl leukotrienes involved in allergic responses in human skin Clin Exp Allergy 2002 32 : 1013 1019.