Mannose hyperbranched dendritic polymers interact with clustered organization of DC-SIGN and inhibit gp120 binding

FEBS Letters

Volumn 580, Issue 10, 2006, Pages 2402-2408

  Tabarani, Georges ^a   Reina, José J ^b   Ebel, Christine ^a   Vivès, Corinne ^a   Lortat Jacob, Hugues ^a   Rojo, Javier ^b   Fieschi, Franck ^a  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

Author keywords

Antiviral compound; Carbohydrates; DC SIGN; gp120; Multivalency; Surface plasmon resonance

Indexed keywords

ANTIVIRUS AGENT; BOLTORN HYPERBRANCHED DENDRITIC POLYMER 20; BOLTORN HYPERBRANCHED DENDRITIC POLYMER 30; DENDRIMER; DENDRITIC CELL SPECIFIC ICAM 3 GRABBING NON INTEGRIN; GLYCOPROTEIN GP 120; LECTIN; MANNOSE; POLYMER; UNCLASSIFIED DRUG; BIOPOLYMER; CD209 ANTIGEN; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; DC-SPECIFIC ICAM-3 GRABBING NONINTEGRIN;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; COMPLEX FORMATION; CONCENTRATION RESPONSE; DENDRITIC CELL; DRUG EFFECT; DRUG PROTEIN BINDING; IC 50; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN DOMAIN; SURFACE PLASMON RESONANCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; SOLUTION AND SOLUBILITY;

BIOPOLYMERS; CELL ADHESION MOLECULES; HIV ENVELOPE PROTEIN GP120; LECTINS, C-TYPE; MANNOSE; MOLECULAR STRUCTURE; RECEPTORS, CELL SURFACE; SOLUTIONS;

EID: 33646931865     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.03.061     Document Type: Article

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