Gabapentin may cause reversible visual field constriction

British Medical Journal

Volumn 332, Issue 7551, 2006, Pages 1193-

  Bekkelund, Svein Ivar ^a   Lilleng, Hallvard ^a   Tønseth, Stig ^b  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b Centre of Ophthalmology   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; GABAPENTIN; TIAGABINE; VIGABATRIN; 4 AMINOBUTYRIC ACID; AMINE; ANALGESIC AGENT; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE;

ADULT; ARTICLE; CASE REPORT; CLINICAL EXAMINATION; DIZZINESS; DOSE RESPONSE; ELECTRORETINOGRAPHY; FEMALE; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYNEUROPATHY; PRIORITY JOURNAL; VISUAL FIELD DEFECT; CHEMICALLY INDUCED DISORDER; LEG; MIDDLE AGED; PAIN; SCOTOMA;

AMINES; ANALGESICS; CYCLOHEXANECARBOXYLIC ACIDS; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; LEG; MIDDLE AGED; PAIN; SCOTOMA;

EID: 33646929537     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Eke T, Talbot JF, Lawden MC. Severe persistent visual field constriction associated with vigabatrin. BMJ 1997;314:180-1.
2. Kälviäinen R, Nousiainen I, Mäntyjärvi M, Nikoskelainen E, Partanen J, Partanen K, et al. A gabaergic antiepileptic drug causes concentric visual field defects. Neurology 1999;53:922-6.
3. Sills GJ, Parsalos PN, Butler E, Forrest G, Ratnaraj N, Brodie MJ. Visual field constriction: accumulation of vigabatrin but not tiagabine in the retina. Neurology 2001;57:196-200.
4. Lawden MC. Vigabatrin, tiagabine, and visual fields. J Neurol Neurosurg Psychiatry 2003;74:286.