Effect of temperature on the retention of ionizable compounds in reversed-phase liquid chromatography: Application to method development

Journal of Chromatography A

Volumn 1118, Issue 2, 2006, Pages 234-243

  Heinisch, Sabine ^a   Puy, Guillaume ^a   Barrioulet, Marie Pierre ^a   Rocca, Jean Louis ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

High temperature; Ionizable compounds; Liquid chromatography; Method development; Retention behaviour

Indexed keywords

COMPUTATIONAL METHODS; HIGH TEMPERATURE OPERATIONS; IONIZATION; LIQUID CHROMATOGRAPHY; SEPARATION; THERMAL EFFECTS;

HIGH TEMPERATURE; IONIZABLE COMPOUNDS; METHOD DEVELOPMENT; RETENTION BEHAVIOUR;

PHARMACODYNAMICS;

AMITRIPTYLINE; AMOXAPINE; BENZENE; BUFFER; CHLOROPROCAINE; CLOZAPINE; CODEINE; DIPHENHYDRAMINE; IMIPRAMINE; PHENOL; PROTRIPTYLINE; QUININE; URACIL;

ARTICLE; DISSOCIATION CONSTANT; DRUG DETERMINATION; HIGH TEMPERATURE; LOW TEMPERATURE; PHYSICAL PHASE; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLUTE; TEMPERATURE SENSITIVITY; THEORETICAL MODEL;

ALGORITHMS; CHROMATOGRAPHY, LIQUID; HYDROGEN-ION CONCENTRATION; IONS; TEMPERATURE; THERMODYNAMICS;

EID: 33646929252     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.03.112     Document Type: Article

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