-
1
-
-
0017370183
-
Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis
-
Ausprunk D.H., and Folkman J. Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc Res 14 (1977) 53-65
-
(1977)
Microvasc Res
, vol.14
, pp. 53-65
-
-
Ausprunk, D.H.1
Folkman, J.2
-
2
-
-
0036984640
-
Role of angiogenesis in tumor growth and metastasis
-
Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol 29 (2002) 15-18
-
(2002)
Semin Oncol
, vol.29
, pp. 15-18
-
-
Folkman, J.1
-
3
-
-
0141988568
-
Fundamental concepts of the angiogenic process
-
Folkman J. Fundamental concepts of the angiogenic process. Curr Mol Med 3 (2003) 643-651
-
(2003)
Curr Mol Med
, vol.3
, pp. 643-651
-
-
Folkman, J.1
-
4
-
-
12344274486
-
The biology of vascular endothelial growth factors
-
Tammela T., Enholm B., Alitalo K., et al. The biology of vascular endothelial growth factors. Cardiovasc Res 65 (2005) 550-563
-
(2005)
Cardiovasc Res
, vol.65
, pp. 550-563
-
-
Tammela, T.1
Enholm, B.2
Alitalo, K.3
-
5
-
-
16644395747
-
The role of VEGF in the regulation of physiological and pathological angiogenesis
-
Ferrara N. The role of VEGF in the regulation of physiological and pathological angiogenesis. EXS 94 (2005) 209-231
-
(2005)
EXS
, Issue.94
, pp. 209-231
-
-
Ferrara, N.1
-
6
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin D.J., and Ellis L.M. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 23 (2005) 1011-1027
-
(2005)
J Clin Oncol
, vol.23
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
7
-
-
4344692045
-
Constitutive and inducible expression and regulation of vascular endothelial growth factor
-
Xie K., Wei D., Shi Q., et al. Constitutive and inducible expression and regulation of vascular endothelial growth factor. Cytokine Growth Factor Rev 15 (2004) 297-324
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 297-324
-
-
Xie, K.1
Wei, D.2
Shi, Q.3
-
8
-
-
0036842215
-
Vascular permeability factor/vascular endothelial growth factor. A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
-
Dvorak H.F. Vascular permeability factor/vascular endothelial growth factor. A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 20 (2002) 4368-4380
-
(2002)
J Clin Oncol
, vol.20
, pp. 4368-4380
-
-
Dvorak, H.F.1
-
9
-
-
0034306974
-
Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
-
Lee C.G., Heijn M., di Tomaso E., et al. Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res 60 (2000) 5565-5570
-
(2000)
Cancer Res
, vol.60
, pp. 5565-5570
-
-
Lee, C.G.1
Heijn, M.2
di Tomaso, E.3
-
10
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
Geng L., Donnelly E., McMahon G., et al. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res 61 (2001) 2413-2419
-
(2001)
Cancer Res
, vol.61
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
-
11
-
-
0033564974
-
Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation
-
Gorski D., Beckett M.A., Jaskowiak N., et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 59 (1999) 3374-3378
-
(1999)
Cancer Res
, vol.59
, pp. 3374-3378
-
-
Gorski, D.1
Beckett, M.A.2
Jaskowiak, N.3
-
12
-
-
0035555907
-
Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth
-
Hess C., Vuong V., Hegyi I., et al. Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth. Br J Cancer 85 (2001) 2010-2016
-
(2001)
Br J Cancer
, vol.85
, pp. 2010-2016
-
-
Hess, C.1
Vuong, V.2
Hegyi, I.3
-
13
-
-
19444378359
-
Use of angiogenesis inhibitors in tumour treatment
-
Fayette J., Soria J.C., and Armand J.P. Use of angiogenesis inhibitors in tumour treatment. Eur J Cancer 41 (2005) 1109-1116
-
(2005)
Eur J Cancer
, vol.41
, pp. 1109-1116
-
-
Fayette, J.1
Soria, J.C.2
Armand, J.P.3
-
14
-
-
2942590261
-
Vascular endothelial growth factor as a target for anticancer therapy
-
Ferrara N. Vascular endothelial growth factor as a target for anticancer therapy. Oncologist 9 Suppl. 1 (2004) 2-10
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 1
, pp. 2-10
-
-
Ferrara, N.1
-
15
-
-
23444435294
-
Clinical implications of antiangiogenic therapies
-
Hudis C.A. Clinical implications of antiangiogenic therapies. Oncology (Williston Park) 19 (2005) 26-31
-
(2005)
Oncology (Williston Park)
, vol.19
, pp. 26-31
-
-
Hudis, C.A.1
-
16
-
-
23444460271
-
Antiangiogenic therapy for cancer. Current and emerging concepts
-
Jain R.K. Antiangiogenic therapy for cancer. Current and emerging concepts. Oncology (Williston Park) 19 (2005) 7-16
-
(2005)
Oncology (Williston Park)
, vol.19
, pp. 7-16
-
-
Jain, R.K.1
-
17
-
-
23444443230
-
Antiangiogenic agents in cancer therapy
-
Lenz H.J. Antiangiogenic agents in cancer therapy. Oncology (Williston Park) 19 (2005) 17-25
-
(2005)
Oncology (Williston Park)
, vol.19
, pp. 17-25
-
-
Lenz, H.J.1
-
18
-
-
0031870833
-
The pivotal role of VEGF in tumor angiogenesis. Molecular facts and therapeutic opportunities
-
Siemeister G., Martiny-Baron G., and Marme D. The pivotal role of VEGF in tumor angiogenesis. Molecular facts and therapeutic opportunities. Cancer Metastasis Rev 17 (1998) 241-248
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 241-248
-
-
Siemeister, G.1
Martiny-Baron, G.2
Marme, D.3
-
19
-
-
0031870832
-
Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy
-
Witte L., Hicklin D.J., Zhu Z., et al. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy. Cancer Metastasis Rev 17 (1998) 155-161
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 155-161
-
-
Witte, L.1
Hicklin, D.J.2
Zhu, Z.3
-
20
-
-
0034000699
-
VEGF receptor signaling in tumor angiogenesis
-
McMahon G. VEGF receptor signaling in tumor angiogenesis. The Oncologist 5 Suppl. 1 (2000) 3-10
-
(2000)
The Oncologist
, vol.5
, Issue.SUPPL. 1
, pp. 3-10
-
-
McMahon, G.1
-
21
-
-
0035793623
-
Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants
-
Gille H., Kowalski J., Li B., et al. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem 276 (2001) 3222-3230
-
(2001)
J Biol Chem
, vol.276
, pp. 3222-3230
-
-
Gille, H.1
Kowalski, J.2
Li, B.3
-
22
-
-
0037115405
-
ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases
-
Carlomagno F., Vitagliano D., Guida T., et al. ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases. Cancer Res 62 (2002) 7284-7290
-
(2002)
Cancer Res
, vol.62
, pp. 7284-7290
-
-
Carlomagno, F.1
Vitagliano, D.2
Guida, T.3
-
23
-
-
0037386774
-
Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase
-
Ciardiello F., Caputo R., Damiano V., et al. Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase. Clin Cancer Res 9 (2003) 1546-1556
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1546-1556
-
-
Ciardiello, F.1
Caputo, R.2
Damiano, V.3
-
24
-
-
0037102369
-
ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
-
Wedge S.R., Ogilvie D.J., Dukes M., et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res 62 (2002) 4645-4655
-
(2002)
Cancer Res
, vol.62
, pp. 4645-4655
-
-
Wedge, S.R.1
Ogilvie, D.J.2
Dukes, M.3
-
25
-
-
1642515721
-
ZD-6474. AstraZeneca
-
Bates D. ZD-6474. AstraZeneca. Curr Opin Investig Drugs 4 (2003) 1468-1472
-
(2003)
Curr Opin Investig Drugs
, vol.4
, pp. 1468-1472
-
-
Bates, D.1
-
26
-
-
18244387980
-
A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer
-
Miller K.D., Trigo J.M., Wheeler C., et al. A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer. Clin Cancer Res 11 (2005) 3369-3376
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3369-3376
-
-
Miller, K.D.1
Trigo, J.M.2
Wheeler, C.3
-
27
-
-
1842689545
-
Targeting the tumor vasculature. A strategy to improve radiation therapy
-
Siemann D.W., and Horsman M.R. Targeting the tumor vasculature. A strategy to improve radiation therapy. Expert Rev Anticancer Ther 4 (2004) 321-327
-
(2004)
Expert Rev Anticancer Ther
, vol.4
, pp. 321-327
-
-
Siemann, D.W.1
Horsman, M.R.2
-
29
-
-
12244252749
-
Gene therapy delivery of endostatin enhances the treatment efficacy of radiation
-
Shi W., Teschendorf C., Muzyczka N., et al. Gene therapy delivery of endostatin enhances the treatment efficacy of radiation. Radiother Oncol 66 (2003) 1-9
-
(2003)
Radiother Oncol
, vol.66
, pp. 1-9
-
-
Shi, W.1
Teschendorf, C.2
Muzyczka, N.3
-
30
-
-
11844272606
-
Wilcoxon-type rank-sum precedence tests
-
Ng H.K.T., and Balakrishnan N. Wilcoxon-type rank-sum precedence tests. Austral N Z J Stat 46 (2004) 631-648
-
(2004)
Austral N Z J Stat
, vol.46
, pp. 631-648
-
-
Ng, H.K.T.1
Balakrishnan, N.2
-
31
-
-
0036648424
-
Inhibition of renal cell carcinoma angiogenesis and growth by antisense oligonucleotides targeting vascular endothelial growth factor
-
Shi W., and Siemann D.W. Inhibition of renal cell carcinoma angiogenesis and growth by antisense oligonucleotides targeting vascular endothelial growth factor. Br J Cancer 87 (2002) 119-126
-
(2002)
Br J Cancer
, vol.87
, pp. 119-126
-
-
Shi, W.1
Siemann, D.W.2
-
32
-
-
11144223542
-
ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy. Schedule-dependent enhancement of antitumor activity
-
Williams K.J., Telfer B.A., Brave S., et al. ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy. Schedule-dependent enhancement of antitumor activity. Clin Cancer Res 10 (2004) 8587-8593
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8587-8593
-
-
Williams, K.J.1
Telfer, B.A.2
Brave, S.3
-
33
-
-
27744553032
-
Targeting the tumor vasculature. Enhancing antitumor efficacy through combination treatment with ZD6126 and ZD6474
-
Shi W., and Siemann D.W. Targeting the tumor vasculature. Enhancing antitumor efficacy through combination treatment with ZD6126 and ZD6474. In Vivo 19 (2005) 1045-1050
-
(2005)
In Vivo
, vol.19
, pp. 1045-1050
-
-
Shi, W.1
Siemann, D.W.2
-
34
-
-
10744223116
-
Experimental study on different combination schedules of VEGF-receptor inhibitor PTK787/ZK222584 and fractionated irradiation
-
Zips D., Krause M., Hessel F., et al. Experimental study on different combination schedules of VEGF-receptor inhibitor PTK787/ZK222584 and fractionated irradiation. Anticancer Res 23 (2003) 3869-3876
-
(2003)
Anticancer Res
, vol.23
, pp. 3869-3876
-
-
Zips, D.1
Krause, M.2
Hessel, F.3
-
35
-
-
0035476866
-
The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors. Potential therapy for cancer
-
Rusnak D.W., Affleck K., Cockerill S.G., et al. The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors. Potential therapy for cancer. Cancer Res 61 (2001) 7196-7203
-
(2001)
Cancer Res
, vol.61
, pp. 7196-7203
-
-
Rusnak, D.W.1
Affleck, K.2
Cockerill, S.G.3
-
36
-
-
0043025225
-
Arginine deiminase and other antiangiogenic agents inhibit unfavorable neuroblastoma growth. Potentiation by irradiation
-
Gong H., Pottgen C., Stuben G., et al. Arginine deiminase and other antiangiogenic agents inhibit unfavorable neuroblastoma growth. Potentiation by irradiation. Int J Cancer 106 (2003) 723-728
-
(2003)
Int J Cancer
, vol.106
, pp. 723-728
-
-
Gong, H.1
Pottgen, C.2
Stuben, G.3
-
37
-
-
2542628099
-
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
-
Tong R.T., Boucher Y., Kozin S.V., et al. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res 64 (2004) 3731-3736
-
(2004)
Cancer Res
, vol.64
, pp. 3731-3736
-
-
Tong, R.T.1
Boucher, Y.2
Kozin, S.V.3
-
38
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy. A new paradigm for combination therapy
-
Jain R.K. Normalizing tumor vasculature with anti-angiogenic therapy. A new paradigm for combination therapy. Nat Med 7 (2001) 987-989
-
(2001)
Nat Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
39
-
-
0035341343
-
Effect of ionizing radiation on thymidine uptake, differentiation, and VEGFR2 receptor expression in endothelial cells. The role of VEGF(165)
-
Kermani P., Leclerc G., Martel R., et al. Effect of ionizing radiation on thymidine uptake, differentiation, and VEGFR2 receptor expression in endothelial cells. The role of VEGF(165). Int J Radiat Oncol Biol Phys 50 (2001) 213-220
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.50
, pp. 213-220
-
-
Kermani, P.1
Leclerc, G.2
Martel, R.3
-
40
-
-
0038176480
-
Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents. Exploring mechanisms of interaction
-
Wachsberger P., Burd R., and Dicker A. Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents. Exploring mechanisms of interaction. Clin Cancer Res 9 (2003) 1957-1971
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1957-1971
-
-
Wachsberger, P.1
Burd, R.2
Dicker, A.3
-
41
-
-
0038443099
-
Anti-angiogenic therapy. Rationale, challenges, and clinical studies
-
Longo R., Sarmiento R., Fanelli M., et al. Anti-angiogenic therapy. Rationale, challenges, and clinical studies. Angiogenesis 5 (2002) 237-256
-
(2002)
Angiogenesis
, vol.5
, pp. 237-256
-
-
Longo, R.1
Sarmiento, R.2
Fanelli, M.3
|