Successful report of reduced-intensity stem cell transplantation from unrelated umbilical cord blood in a girl with chronic active Epstein-Barr virus infection

Journal of Pediatric Hematology/Oncology

Volumn 28, Issue 4, 2006, Pages 254-256

  Iguchi, Akihiro ^a   Kobayashi, Ryoji ^a   Sato, Tomonobu Z ^a   Nakajima, Masahide ^a   Kaneda, Makoto ^a   Ariga, Tadashi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Chronic active Epstein Barr virus infection (CAEBV); Cord blood (CB); Reduced intensity stem cell transplantation (RIST)

Indexed keywords

ANTIINFECTIVE AGENT; AZATHIOPRINE; CYCLOSPORIN; ETOPOSIDE; FLUDARABINE; HLA ANTIGEN; HLA DR ANTIGEN; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; PREDNISOLONE; STEROID; TACROLIMUS;

ABDOMINAL PAIN; ACUTE GRAFT VERSUS HOST DISEASE; ARTICLE; BLOOD DONOR; CASE REPORT; CHEMOTHERAPY; CHRONIC ACTIVE EPSTEIN BARR VIRUS INFECTION; CHRONIC GRAFT VERSUS HOST DISEASE; CLINICAL FEATURE; CORD BLOOD STEM CELL TRANSPLANTATION; EPSTEIN BARR VIRUS; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTERSTITIAL LYMPHADENOPATHY; LUNG DISEASE; LYMPHADENOPATHY; MYELOABLATIVE CONDITIONING; PRIORITY JOURNAL; RADIATION DOSE; REDUCED INTENSITY CONDITIONING; SCHOOL CHILD; SKIN MANIFESTATION; TREATMENT OUTCOME; UMBILICAL CORD BLOOD; VIRUS DETECTION; VIRUS INFECTION; WHOLE BODY RADIATION;

BLOOD TRANSFUSION; BONE MARROW; CHILD; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; FETAL BLOOD; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOSUPPRESSIVE AGENTS; STEM CELL TRANSPLANTATION; TRANSPLANTATION CHIMERA; TREATMENT OUTCOME;

EID: 33646907996     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/01.mph.0000212916.29889.c2     Document Type: Article

References (10)

1. Ishihara S, Okada S, Wakiguchi H, et al. Chronic active Epstein-Barr virus infection in children in Japan. Acta Paediatr. 1995;84:1271-1275.
2. Yoshioka M, Ishiguro N, Ishiko H, et al. Heterogeneous, restricted patterns of Epstein-Barr virus (EBV) latent gene expression in patients with chronic active EBV infection. J Gen Virol. 2001;82:2385-2392.
3. Yoshioka M, Kikuta H, Ishiguro N, et al. Unique Epstein-Barr virus (EBV) latent gene expression, EBNA promoter usage and EBNA promoter methylation status in chronic active EBV infection. J Gen Virol. 2003;84:1133-1140.
4. Kikuta H, Sakiyama Y. Etoposide (VP-16) inhibits Epstein-Barr virus determined nuclear antigen (EBNA) synthesis. Br J Haematol. 1995;90:971-973.
5. Chen JS, Lin KH, Lin DT, et al. Longitudinal observation and outcome of nonfamilial childhood haemophagocytic syndrome receiving etoposide-containing regimens. Br J Haematol. 1998;103:756-762.
6. Fujii N, Takenaka K, Hiraki A, et al. Allogeneic peripheral blood stem cell transplantation for the treatment of chronic active Epstein-Barr virus infection. Bone Marrow Transplant. 2000;26:805-808.
7. Taketani T, Kikuchi A, Inatomi J, et al. Chronic active Epstein-Barr virus infection (CAEBV) successfully treated with allogeneic peripheral blood stem cell transplantation. Bone Marrow Transplant. 2002;29:531-533.
8. Ebihara Y, Manabe A, Tanaka R, et al. Successful treatment of natural killer (NK) cell leukemia following a long-standing chronic active Epstein-Barr virus (CAEBV) infection with allogeneic bone marrow transplantation. Bone Marrow Transplant. 2003;31:1169-1171.
9. Sakata N, Sato E, Sawada A, et al. Chronic active Epstein-Barr virus infection treated with reduced intensity stem cell transplantation. Rinsho Ketsueki. 2004;45:393-396.
10. Uehara T, Nakaseko C, Hara S, et al. Successful control of Epstein-Barr virus (EBV)-infected cells by allogeneic nonmyeloablative stem cell transplantation in a patient with the lethal form of chronic active EBV infection. Am J Hematol. 2004;76:368-372.