Kinetics of US28 gene expression during active human cytomegalovirus infection in lung-transplant recipients

Journal of Infectious Diseases

Volumn 193, Issue 11, 2006, Pages 1552-1556

  Boomker, Jasper M ^a,c   Verschuuren, Erik A M ^b   Brinker, Marja G L ^a,c   De Leij, Lou F M H ^a,c   Hauw The, T ^b   Harmsen, Martin C ^a,b,c  

^a Medical Biology Section ^*  (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AZATHIOPRINE; COTRIMOXAZOLE; CYCLOSPORIN A; CYTOMEGALOVIRUS ANTIBODY; FOSCARNET; FOSCARNET SODIUM; GANCICLOVIR; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; TACROLIMUS; THYMOCYTE ANTIBODY;

ACUTE GRAFT REJECTION; ADULT; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; GENETIC TRANSCRIPTION; HERPES VIRUS INFECTION; HUMAN; HUMAN CYTOMEGALOVIRUS; IMMEDIATE EARLY 1 GENE; IMMEDIATE EARLY GENE; IMMUNOSUPPRESSIVE TREATMENT; KINETICS; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; PNEUMOCYSTOSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; US28 GENE; VIRUS GENE; VIRUS REPLICATION;

ADULT; ANTIGENS, VIRAL; CYTOMEGALOVIRUS INFECTIONS; GENE EXPRESSION; HUMANS; IMMEDIATE-EARLY PROTEINS; KINETICS; LUNG TRANSPLANTATION; MIDDLE AGED; PHOSPHOPROTEINS; RECEPTORS, CHEMOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRAL MATRIX PROTEINS; VIRAL PROTEINS;

EID: 33646905628     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/503779     Document Type: Article

References (19)

1. Fishman JA, Rubin RH. Infection in organ-transplant recipients. N Engl J Med 1998; 338:1741-51.
2. Beisser PS, Goh CS, Cohen FE, Michelson S. Viral chemokine receptors and chemokines in human cytomegalovirus trafficking and interaction with the immune system: CMV chemokine receptors. Curr Top Microbiol Immunol 2002; 269:203-34.
3. Boomker JM, van Luyn MJ, The TH, de Leij LF, Harmsen MC. US28 actions in HCMV infection: lessons from a versatile hijacker. Rev Med Virol 2005; 15:1-14.
4. Zipeto D, Bodaghi B, Laurent L, Virelizier JL, Michelson S. Kinetics of transcription of human cytomegalovirus chemokine receptor US28 in different cell types. J Gen Virol 1999; 80:543-7.
5. Beisser PS, Laurent L, Virelizier JL, Michelson S. Human cytomegalovirus chemokine receptor gene US28 is transcribed in latently infected THP-1 monocytes. J Virol 2001; 75:5949-57.
6. Billstrom MA, Johnson GL, Avdi NJ, Worthen GS. Intracellular signaling by the chemokine receptor US28 during human cytomegalovirus infection. J Virol 1998; 72:5535-44.
7. Streblow DN, Soderberg-Nauder C, Vieira J, et al. The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration. Cell 1999; 99:511-20.
8. Streblow DN, Orloff SL, Nelson JA. The HCMV chemokine receptor US28 is a potential target in vascular disease. Curr Drug Targets Infect Disord 2001; 1:151-8.
9. Kledal TN, Rosenkilde MM, Schwartz TW. Selective recognition of the membrane-bound CX3C chemokine, fractalkine, by the human cytomegalovirus-encoded broad-spectrum receptor US28. FEBS Lett 1998; 441:209-14.
10. Casarosa P, Bakker RA, Verzijl D, et al. Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28. J Biol Chem 2001; 276:1133-7.
11. McLean KA, Holst PJ, Martini L, Schwartz TW, Rosenkilde MM. Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74. Virology 2004; 325: 241-51.
12. Boomker JM, The TH, de Leij LF, Harmsen MC. The human cytomegalovirus-encoded receptor US28 increases the activity of the major immediate-early promoter/enhancer. Virus Res 2006; 28 January [electronically published ahead of print].
13. Casarosa P, Menge WM, Minisini R, et al. Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor. J Biol Chem 2003; 278:5172-8.
14. Greijer AE, Adriaanse HM, Dekkers CA, Middeldorp JM. Multiplex real-time NASBA for monitoring expression dynamics of human cytomegalovirus encoded IE1 and pp67 RNA. J Clin Virol 2002; 24:57-66.
15. The TH, Harmsen MC, van der Bij W, van den Berg AP, van Son W. Relationship between monitoring the viral load in blood, human cytomegalovirus pathophysiology and management strategies of patients after transplantation. In: Scholz M, Rabenau HF, Doerr HW, Cinatl J Jr, eds. CMV-related immunopathology. Basel: Karger, 1998:262-79.
16. van der Giessen M, van den Berg AP, van der Bij W, Postma S, van Son WJ, The TH. Quantitative measurement of cytomegalovirus-specific IgG and IgM antibodies in relation to cytomegalovirus antigenaemia and disease activity in kidney recipients with an active cytomegalovirus infection. Clin Exp Immunol 1990; 80:56-61.
17. Boom R, Sol CJ, Salimans MM, Jansen CL, Wertheim-van Dillen PM, van der Noordaa J. Rapid and simple method for purification of nucleic acids. J Clin Microbiol 1990; 28:495-503.
18. Greijer AE, Verschuuren EA, Dekkers CA, et al. Expression dynamics of human cytomegalovirus immune evasion genes US3, US6, and US11 in the blood of lung transplant recipients. J Infect Dis 2001; 184:247-55.
19. Pleskoff O, Casarosa P, Verneuil L, et al. The human cytomegalovirus- encoded chemokine receptor US28 induces caspase-dependent apoptosis. FEBS J 2005; 272:4163-77.