Insights into the role of electrostatic forces on the behavior of dry pharmaceutical particulate systems

Pharmaceutical Research

Volumn 23, Issue 5, 2006, Pages 997-1007

  DesRosiers Lachiver, Emilie ^a,b   Abatzoglou, Nicolas ^a   Cartilier, Louis ^c   Simard, Jean Sébastien ^b  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Electrostatic forces; Flow; Lubricant; Mixing; Powders

Indexed keywords

CALCIUM PHOSPHATES; CHEMISTRY, PHARMACEUTICAL; ELECTROSTATICS; EXCIPIENTS; HUMIDITY; PLASTICS; POWDERS; STAINLESS STEEL; STATIC ELECTRICITY; STEARIC ACIDS; SWEETENING AGENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 33646893051     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9934-0     Document Type: Article

References (17)

1. L. H. Cartilier A. J. Moës 1989 Effect of drug agglomerates upon the kinetics of mixing of low dosage cohesive powder mixtures Drug Dev. Ind. Pharm. 15 12 1911 1931
2. G. Rowley 2001 Quantifying electrostatic interactions in pharmaceutical solid systems Int. J. Pharm. 227 47 55
3. W. A. D. Rudge 1913 On the electrification associated with dust-clouds Philos. Mag. 25 481 494
4. J. N. Staniforth J. E. Rees 1982 Electrostatic charge interactions in ordered powder mixes J. Pharm. Pharmacol. 34 69 76
5. F. Muzzio and A. Alexander. Scale up of powder-blending operations. Pharm. Technol. 34-42 (March 2005).
6. C. U. Yurteri M. K. Mazumder N. Grable 2002 Electrostatic effects on dispersion, transport, and deposition of fine pharmaceutical powders: development of an experimental method for quantitative analysis Part. Sci. Technol. 20 59 79
7. A. G. Bailey 1984 Electrostatic phenomena during powder handling Powder Technol. 37 71 81
8. D. C. Montgomery 2001 Design and Analysis of Experiments 5 Wiley New York 684
9. C. Merle. Contribution à l'étude et à l'élimination de l'électricité statique en technologie des poudres. Thèse pour l'obtention du Doctorat d'État en Pharmacie, Université de Lille, March 1975 (French).
10. L. B. Loeb 1958 Static Electrification Springer Berlin Heidelberg New York
11. W. B. Kunkel 1950 The static electrification of dust particles on dispersion into a cloud J. Appl. Phys. 21 820
12. R. P. Bhatia N. G. Lordi 1979 Electrical conductance of directly compressible materials under pressure J. Pharm. Sci. 68 2 222 226
13. H. Vromans G. K. Bolhuis C. F. Lerk 1988 Magnesium stearate susceptibility of directly compressible materials as an indication of fragmentation properties Powder Technol. 54 39 44
14. J. C. Carter 2002 Pre-blends: why do we do them? Pharm. Can. 3 3 27 28
15. L. Roblot-Treupel F. Puissieux 1986 Distribution of magnesium stearate on the surface of lubricated particles Int. J. Pharm. 31 131 136
16. E. B. Mpenza. Électricité statique en technologie des poudres pharmaceutiques: sa mesure, son élimination et son influence. Thèse pour l'obtention du grade de Docteur en Sciences Pharmaceutiques, Université Catholique de Louvain, 1981 (French).
17. F. Podczeck Y. Miah 1996 The influence of particle size and shape on the angle of internal friction and the flow factor of unlubricated and lubricated powders Int. J. Pharm. 144 187 194