Toremifene for premenstrual mastalgia: A randomised, placebo-controlled crossover study

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 113, Issue 6, 2006, Pages 713-718

  Oksa, S ^a   Luukkaala, T ^b   Maenpaa J ^c  

^a SATAKUNTA CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF TAMPERE   (Finland)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Mastalgia; Premenstrual syndrome; Selective oestrogen receptor modulators; Toremifene

Indexed keywords

TOREMIFENE;

ADULT; AGE DISTRIBUTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; EVALUATION; FEMALE; GENERAL PRACTICE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MASTALGIA; MENSTRUAL CYCLE; MENSTRUATION; NAUSEA; PREMENSTRUAL SYNDROME; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; UNIVERSITY HOSPITAL; VISUAL ANALOG SCALE;

ADULT; BREAST DISEASES; CROSS-OVER STUDIES; FEMALE; HUMANS; MENSTRUATION DISTURBANCES; MIDDLE AGED; PAIN; PAIN MEASUREMENT; QUALITY OF LIFE; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TOREMIFENE; TREATMENT OUTCOME;

EID: 33646881017     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2006.00943.x     Document Type: Article

References (26)

1. Ader DN, Browne MW. Prevalence and impact of cyclic mastalgia in a United States clinic-based sample. Am J Obstet Gynecol 1997 177 : 126 32.
2. Millet AV, Dirbas FM. Clinical management of breast pain: a review. Obstet Gynecol Surv 2002 57 : 451 61.
3. Goodwin PJ, Miller A, Del Giudice ME, Ritchie K. Breast health and associated premenstrual symptoms in women with severe cyclic mastopathy. Am J Obstet Gynecol 1997 176 : 998 1005.
4. Johnson SR. Premenstrual syndrome, premenstrual dysphoric disorder, and beyond: a clinical primer for practioners. Obstet Gynecol 2004 104 : 845 59.
5. Smith RL, Pruthi S, Fitzpatrick LA. Evaluation and management of breast pain. Mayo Clin Proc 2004 79 : 353 72.
6. Mansel RE. Breast pain. BMJ 1994 309 : 866 8.
7. BeLieu RM. Mastodynia. Obstet Gynecol Clin North Am 1994 21 : 461 7.
8. Mansel RE, Dogliotti L. European multicentre trial of bromocriptine in cyclical mastalgia. Lancet 1990 335 : 190 3.
9. O'Brien PM, Abukhalil IE. Randomized controlled trial of the management of premenstrual syndrome and premenstrual mastalgia using luteal phase-only danazol. Am J Obstet Gynecol 1999 180 : 18 23.
10. Mansel RE, Goyal A, Preece P, Leinster S, Maddox PR, Gateley C, et al. European randomized, multicenter study of goserelin (Zoladex) in the management of mastalgia. Am J Obstet Gynecol 2004 191 : 1942 9.
11. Fentiman IS, Caleffi M, Hamed H, Chaudary MA. Dosage and duration of tamoxifen treatment for mastalgia: a controlled trial. Br J Surg 1988 75 : 845 6.
12. Messinis IE, Lolis D. Treatment of premenstrual mastalgia with tamoxifen. Acta Obstet Gynecol Scand 1988 67 : 307 9.
13. Kontostolis E, Stefanidis K, Navrozoglou I, Lolis D. Comparison of tamoxifen with danazol for treatment of cyclical mastalgia. Gynecol Endocrinol 1997 11 : 393 7.
14. DeGregorio MW, Maenpaa JU, Wiebe VJ. Tamoxifen for the prevention of breast cancer: no. In : DeVita VT, Hellman S, Rosenberg SA, editors. Important Advances in Oncology 1995. Philadelphia, PA : JB Lippincott Company 1995. p. 175 85.
15. Braithwaite RC, Chlebowski RT, Lau J, George S, Hess R, Col NF. Meta-analysis of vascular and neoplastic events associated with tamoxifen. J Gen Intern Med 2003 18 : 937 47.
16. Hayes DF, Van Zyl JA, Hacking A, Goedhals L, Bezwoda WR, Mailliard JA, et al. Randomized comparison of tamoxifen and two separate doses of toremifene in postmenopausal patients with metastatic breast cancer. J Clin Oncol 1995 13 : 2556 66.
17. Holli K, Valavaara R, Blanco G, Kataja V, Hietanen P, Flander M, et al. Safety and efficacy results of a randomized trial comparing adjuvant toremifene and tamoxifen in postmenopausal patients with node-positive breast cancer. J Clin Oncol 2000 18 : 3487 94.
18. Marttunen MB, Cacciatore B, Hietanen P, Pyrhonen S, Tiitinen A, Wahlstrom T, et al. Prospective study on gynaecological effects of two antioestrogens tamoxifen and toremifene in postmenopausal women. Br J Cancer 2001 84 : 897 902.
19. Tomás E, Kauppila A, Blanco G, Apaja-Sarkkinen M, Laatikainen T. Comparison between the effects of tamoxifen and toremifene on the uterus in postmenopausal breast cancer patients. Gynecol Oncol 1995 59 : 261 6.
20. Hirsimaki P, Aaltonen A, Mantyla E. Toxicity of antiestrogens. Breast J 2002 8 : 92 6.
21. Pukkala E, Kyyronen P, Sankila R, Holli K. Tamoxifen and toremifene treatment of breast cancer and risk of subsequent endometrial cancer: a population-based case-control study. Int J Cancer 2002 100 : 337 41.
22. Maenpaa J, Holli K, Pasanen T. Toremifene. Where do we stand? Eur J Cancer 2000 36 Suppl 4 S61 2.
23. Erkkola R, Nevala P, Mantyla E. Toremifene and breast cancer therapy: incidence of secondary endometrial cancers. Breast Cancer Res Treat 2002 76 : 636a.
24. Salokangas RKR, Poutanen O, Stengard E. Screening for depression in primary care. Development and validation of the Depression Scale, a screening instrument for depression. Acta Psychiatr Scand 1995 92 : 10 16.
25. Halbreich U, Kahn LS. Treatment of premenstrual dysphoria disorder with luteal phase dosing of sertraline. Expert Opin Pharmacother 2003 4 : 2065 78.
26. Hamed H, Kotheri A, Beechey-Newman N, Fentiman IS. Toremifene, a new agent for treatment of mastalgia: an open study. Int J Fertil Womens Med 2004 49 : 278 80.