Diagnostic and prognosis of overt disseminated intravascular coagulation in a general hospital - Meaning of the isth score system, fibrin monomers, and lipoprotein-C-reactive protein complex formation

American Journal of Hematology

Volumn 81, Issue 6, 2006, Pages 414-419

  Cauchle, Ph ^a,d   Cauchie, Ch ^a   Boudjeltia, K Zouaoui ^a   Carlier, E ^a   Deschepper, N ^a   Govaerts, D ^a   Migaud Fressart, M ^b   Woodhams, B ^c   Brohee D ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Diagnostica Stago ^*  (France)

^c Stago R and D   (France)

^d CHU Andre Vesale   (Belgium)

Author keywords

Biphasic APTT waveform; Disseminated intravascular coagulation; Fibrin monomer; Scoring system; Sepsis

Indexed keywords

ANTITHROMBIN; C REACTIVE PROTEIN; CREATININE; D DIMER; FIBRIN; FIBRIN MONOMER; LIPOPROTEIN; LIPOPROTEIN C REACTIVE PROTEIN; PROTEIN C; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MULTIPROTEIN COMPLEX; PLASMA PROTEIN;

COMPLEX FORMATION; DIAGNOSTIC VALUE; DISEASE MARKER; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; FIBRIN FORMATION; GRAM NEGATIVE INFECTION; HUMAN; INFLAMMATION; LETHALITY; MAJOR CLINICAL STUDY; MEDICAL SOCIETY; PRIORITY JOURNAL; PROGNOSIS; REVIEW; RISK FACTOR; SCORING SYSTEM; SEPSIS; ARTICLE; BLOOD; BLOOD CLOTTING TEST; EVALUATION; FEMALE; GENERAL HOSPITAL; HEMOSTASIS; MALE; MORTALITY; THROMBOSIS;

BIOLOGICAL MARKERS; BLOOD COAGULATION TESTS; BLOOD PROTEINS; DISSEMINATED INTRAVASCULAR COAGULATION; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HEMOSTASIS; HOSPITALS, GENERAL; HUMANS; MALE; MULTIPROTEIN COMPLEXES; PROGNOSIS; RISK FACTORS; SEPSIS; SOCIETIES, MEDICAL; THROMBOSIS;

EID: 33646875104     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.20597     Document Type: Review

References (24)

1. Wada H, Gabazza E, Asakura H, Koike K, Okamato K, Maruyama I, Shiku H, Nobori T. Comparison of diagnostic criteria for disseminated intravascular coagulation (DIC): diagnostic criteria of the International Society of Thrombosis and Haemostasis (ISTH) and the Japanese ministry of health and welfare for overt DIC. Am J Hematol 2003;74:17-22.
2. Taylor FB, Toh CH, Hoots WK, Wada H, Levi M. Towards definition, clinical and laboratory criteria and a scoring system for disseminated intravascular coagulation. Thromb Haemost 2001;86:1327-1330.
3. Levi M. Disseminated intravascular coagulation: what's new? Crit Care Clin 2005;21:449-467.
4. Bakhtiari K, Meijers JC, De Jonge E, Levi M. Prospective assessment of the diagnostic accuracy of the ISTH criteria for the diagnosis of DIC. J Thromb Haemost 2003;1 (Suppl 1):P0621.
5. Downey C, Kazmi R, Toh CH. Novel and diagnostically applicable information from optical waveform analysis of blood coagulation in disseminated intravascular coagulation. Br J Haematol 1997;98(1):68-73.
6. Toh CH, Samis J, Downey C, Walker J, Becker L, Brufatto N, Tejidor L, Jones G, Houdijk W, Giles A, Koschinsky M, Ticknor LO, Paton R, Wenstone R, Nesheim M. Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca(++)-dependent complex of C-reactive protein with very-low-density lipoprotein and is a novel marker of impending disseminated intravascular coagulation Blood 2002; 100(7):2522-2529.
7. Dennis MW, Downey C, Brufatto N, Nesheim ME, Stevenson K, Toh CH. Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein. Thromb Haemost 2004;91(3):522-530.
8. Downey C, Kazmi R, Toh CH. Early identification and prognostic implications in disseminated intravascular coagulation through transmittance waveform analysis. Thromb Haemost 1998;80:65-69.
9. Toh CH, Giles AR. Waveform analysis of clotting test optical profiles in the diagnosis and management of disseminated intravascular coagulation (DIC). Clin Lab Haematol 2002;24(6):321-327.
10. Dempfle CE, Lorenz S, Smolinski M, Wurst M, West S, Houdijk W, Quintel M, Borggrefe M. Utility of activated partial thromboplastin time waveform analysis for identification of sepsis and overt disseminated intravascular coagulation in patients admitted to surgical intensive care unit. Crit Care Med 2004;32(2):520-524.
11. Levy M, Fink M, Marshall J, Abraham E, Angus D, Cook D, Cohen J, Opal S, Vincent JL, Ramsay G. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31(4):1250-1256.
12. Fernandes B, Giles A. An abnormal activated partial thromboplastin time clotting waveform is associated with high mortality and a procoagulant state. Lab Hematol 2003;9(3):138-142.
13. Toh CH, Ticknor LO, Downey C, Giles AR, Paton RC, Wenstone R. Early identification of sepsis and mortality risk through simple, rapid clot-waveform analysis. Intensive Care Med 2003;29:55-61.
14. Smith EY, Charles LA, Van Cott EM. Biphasic activated partial thromboplastin time waveform and adverse events in non-intensive care unit patients. Am J Clin Pathol 2004;121(1):138-141.
15. Samis JA, Stewart KA, Toh CH, Day A, Downey C, Nesheim ME. Temporal changes in factors associated with neutrophil elastase and coagulation in intensive care patients with biphasic waveform and disseminated intravascular coagulation. J Thromb Haemost 2004;2:1535-1544.
16. Carpentier YA, Scruel O. Changes in concentration and composition of plasma lipoproteins during the acute phase response. Curr Opin Clin Nutr Metab Care 2002;5:153-158.
17. Lanza-Jacoby S, Wong SH, Tabares A, Baer D, Scheider T. Disturbance in the composition of plasma lipoproteins during gram-negative sepsis in the rat. Biochim Biophys Acta 1992; 1124:233-240.
18. Toh CH. APTT revisited: detecting dysfunction in the hemostatic system through waveform analysis. Thromb Haemost 1999;82(2):684-687.
19. Toh CH. Transmittance waveform of routine coagulation tests is a sensitive and specific method for diagnosing non-overt disseminated intravascular coagulation. Blood Rev 2002;16 (Suppl 1):S11-S14.
20. Wada H, Matsumoto TM, Sase TS, Nobori TN, Shiku HS, Houdijk WH. Frequency of biphasic transmittance in the APTT coagulation assay in the patients with underlying diseases of DIC. J Thromb Haemost 2003;1 (Suppl 1):P0610.
21. Dempfle C. The use of soluble fibrin in evaluating the acute and chronic hypercoagulable state. Thromb Haemost 1999;82(2):673-683.
22. Wada H, Sase T, Matsumoto T, Kushiya F, Sakakura M, Mori Y, Nishikawa M, Ohnishi K, Nakatani K, Gabazza EC, Shiku H, Nobori T. Increased soluble fibrin in plasma of patients with disseminated intravascular coagulation. Clin Appl Thromb Hemost 2003;9(3):233-240.
23. Demfle CE, Wurst M, Smolinski M, Lorenz S, Osika A, Olenik D, Fiedler F, Borggrefe M. Use of soluble fibrin antigen instead of D-dimer as fibrin-related marker may enhance the prognostic power of the ISTH overt DIC score. Thromb Haemost 2004;91:812-818.
24. Fourrier F, Chopin C, Goudemand J, Hendrycx S, Caron C, Rime A, Marey A, Lestavel P. Septic shoe, multiple organ failure and disseminated intravascular coagulation. Chest 1992;101(3):816-823.