In vivo reactivation of a quiescent cell population located in the ocular ciliary body of adult mammals

Experimental Eye Research

Volumn 83, Issue 1, 2006, Pages 153-164

  Abdouh, Mohamed ^a   Bernier, Gilbert ^a,b  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

adult mammals; ciliary body; growth factors; in vivo activation; iris; stem cells

Indexed keywords

BROXURIDINE; CYCLIN D1; GROWTH FACTOR; HOMEODOMAIN PROTEIN; KI 67 ANTIGEN; NESTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CHX10; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL CYCLE; CELL DIVISION; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CELL SUBPOPULATION; CILIARY BODY; CONTROLLED STUDY; EPITHELIUM CELL; MALE; MAMMAL; NERVOUS SYSTEM DEVELOPMENT; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RETINA INJURY; RETINA NEUROEPITHELIAL LAYER;

ANIMALS; BIOLOGICAL MARKERS; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; CILIARY BODY; CYCLIN D1; EPITHELIAL CELLS; EYE PROTEINS; GROWTH SUBSTANCES; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INJECTIONS; INTERMEDIATE FILAMENT PROTEINS; IRIS; KI-67 ANTIGEN; NERVE TISSUE PROTEINS; NEURONS; PAIRED BOX TRANSCRIPTION FACTORS; RATS; RATS, WISTAR; REPRESSOR PROTEINS; RETINA; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 33646864314     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.11.016     Document Type: Article

References (46)

1. Ahmad I., Tang L., and Pham H. Identification of neural progenitors in the adult mammalian eye. Biochem. Biophys. Res. Commun. 270 (2000) 517-521
2. Akagawa K., and Barnstable C.J. Identification and characterization of cell types in monolayer cultures of rat retina using monoclonal antibodies. Brain Res. 383 (1986) 110-120
3. Akagi T., Mandai M., Ooto S., Hirami Y., Osakada F., Kageyama R., Yoshimura N., and Takahashi M. Otx2 homeobox gene induces photoreceptors-specific phenotypes in cells derived from adult iris and ciliary tissue. Invest. Ophthalmol. Vis. Sci. 45 (2004) 4570-4575
4. Arnhold S., Klein H., Semkova I., Addicks K., and Schraermeyer U. Neurally selected embryonic stem cells induce tumor formation after long-term survival following engraftment into the subretinal space. Invest. Ophthalmol. Vis. Sci. 45 (2004) 4251-4255
5. Beebe D.C. Development of the ciliary body: a brief review. Trans. Ophthalmol. Soc. U. K. 105 (1986) 123-130
6. Belecky-Adams T., Tomarev S., Li H.S., Ploder L., Mcinnes R.R., Sundin O., and Adler R. Pax-6, Prox 1, and Chx10 homeobox gene expression correlates with phenotypic fate of retinal precursor cells. Invest. Ophthalmol. Vis. Sci. 38 (1997) 1293-1303
7. Cayouette M., Whitmore A.V., Jeffery G., and Raff M. Asymmetric segregation of Numb in retinal development and the influence of the pigment epithelium. J. Neurosci. 21 (2001) 5643-5651
8. Cepko C.L. The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Curr. Opin. Neurobiol. 9 (1999) 37-46
9. Clarke G., Heon E., and McInnes R.R. Recent advances in the molecular basis of inherited photoreceptor degeneration. Clin. Genet. 57 (2000) 313-329
10. Coulombre A.J. Organogenesis (1965), Academic Press, New York
11. Del Bigio M.R., and Bruni J.E. Periventricular pathology in hydrocephalic rabbits before and after shunting. Acta Neuropathol. 77 2 (1988) 186-195
12. Del Bigio M.R., and Zhang Y.W. Cell death, axonal damage, and cell birth in the immature rat brain following induction of hydrocephalus. Exp. Neurol. 154 (1998) 157-169
13. Doetsch F., Garcia-Verdugo J.M., and Alvarez-Buylla A. Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci. 17 (1997) 5046-5061
14. Doetsch F., Garcia-Verdugo J.M., and Alvarez-Buylla A. Regeneration of a germinal layer in the adult mammalian brain. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 11619-11624
15. Fischer A.J., and Reh T.A. Identification of a proliferating marginal zone of retinal progenitors in the postnatal chicken. Dev. Biol. 220 (2000) 197-210
16. Fischer A.J., McGuire C.R., Dierks B.D., and Reh T.A. Insulin and fibroblast growth factor 2 activate a neurogenic program in Muller glia of the chicken retina. J. Neurosci. 22 (2002) 9387-9398
17. Fischer A.J., and Reh T.A. Growth factors induce neurogenesis in the ciliary body. Dev. Biol. 259 (2003) 225-240
18. Goldberg J.L., Klassen M.P., Hua Y., and Barres B.A. Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science 296 (2002) 1860-1864
19. Günhan E., van der List D., and Chalupa L.M. Ectopic photoreceptors and cone bipolar cells in the developing and mature retina. Neuroscience 23 (2003) 1383-1389
20. Haruta M., Kosaka M., Kanegae Y., Saito I., Inuoe T., Kageyama R., Nishida A., Honda Y., and Takahashi M. Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue. Nat. Neurosci. 4 (2001) 1163-1164
21. Klein J.A., Longo-Guess C.M., Rossmann M.P., Seburn K.L., Hurd R.E., Frankel W.N., Bronson R.T., and Ackerman S.L. The harlequin mouse mutation down-regulates apoptosis-inducing factor. Nature 419 (2002) 367-374
22. Lehmann M., Fournier A., Selles-Navarro I., Dergham P., Sebok A., Leclerc N., Tigyi G., and McKerracher L. Inactivation of Rho signaling pathway promotes CNS axon regeneration. J. Neurosci. 19 17 (1999) 7537-7547
23. Lendahl U., Zimmerman L.B., and McKay R.D. CNS stem cells express a new class of intermediate filament protein. Cell 60 4 (1990) 585-595
24. Liu I.S.C., Chen J.d., Ploder L., Vidgen D., van der Kooy D., Kalnins V.I., and Mclnnes R.R. Developmental expression of a novel murine homeobox gene (Chx10): Evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron 13 2 (1994) 377-393
25. Lu B., Jan L., and Jan Y.-N. Control of cell division in the nervous system: symmetry and asymmetry. Annu. Rev. Neurosci. 23 (2000) 531-556
26. Malatesta P., Gotz M., Barsacchi G., Price J., Zoncu R., and Cremisi F. PC3 overexpression affects the pattern of cell division of rat cortical precursors. Mech. Dev. 90 1 (2000) 17-28
27. de Melo J., Qiu X., Du G., Cristante L., and Eisenstat D.D. Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina. J. Comp. Neurol. 461 (2003) 187-204
28. Morshead C.M., Craig C.G., and van der Kooy D. In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain. Development 125 (1998) 2251-2261
29. Morshead C.M., Reynolds B.A., Craig C.G., McBurney M.W., Staines W.A., Morassutti D., Weiss S., and van der Kooy D. Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron 13 5 (1994) 1071-1082
30. Moshiri A., and Reh T.A. Persistent progenitors at the retinal margin of ptc+/- mice. J. Neurosci. 24 (2004) 229-237
31. Okabe S., Shiomura Y., and Hirokawa N. Immunocytochemical localization of microtubule-associated proteins 1A and 2 in the rat retina. Brain Res. 483 (1989) 335-346
32. Ooto S., Akagi T., Kageyama R., Akita J., Mandai M., Honda Y., and Takahashi M. Potential for neural regeneration after neurotoxic injury in the adult mammalian retina. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 13654-13659
33. Pacione L.R., Szego M.J., Ikeda S., Nishima P.M., and McInnes R.R. Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations. Annu. Rev. Neurosci. 26 (2003) 657-700
34. Perron M., and Harris W.A. Retinal stem cells in vertebrates. Bioessays 22 (2000) 685-688
35. Raymond P.A., and Hitchcock P.F. Retinal regeneration: common principles but diverse mechanisms. Adv. Neurol. 72 (1997) 171-184
36. Raymond P.A., and Hitchcock P.F. How the neural retina regenerates. Results Probl. Cell. Differ. 31 (2000) 121-197
37. Reh T.A., and Levine E.M. Multipotential stem cells and progenitors in the vertebrate retina. J. Neurobiol. 36 (1998) 206-220
38. Sakai T., Calderone J.B., Lewis G.P., Linberg K.A., Fisher S.K., and Jacobs G.H. Cone photoreceptor recovery after experimental detachment and reattachment: an immunocytochemical, morphological, and electrophysiological study. Invest. Ophthalmol. Vis. Sci. 44 (2003) 416-425
39. Scott I.S., Morris L.S., Bird K., Davies R.J., Vowler S.L., Rushbrook S.M., Marshall A.E., Laskey R.A., Miller R., Arends M.J., and Coleman N. A novel immunohistochemical method to estimate cell-cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer. J. Pathol. 201 2 (2003) 187-197
40. Tropepe V., Coles B.L., Chaisson B.J., Horsford D.J., Elia A.J., Mclnnes R.R., and Van der Kooy D. Retinal stem cells in the adult mammalian eye. Science 287 (2000) 2032-2036
41. Vecchi A., Garlanda C., and Lampugnari M.G. Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium. Eur. J. Cell Biol. 63 (1994) 247-254
42. Walther C., and Gruss P. Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 113 4 (1991) 1435-1449
43. Watanabe M., Rutishauser U., and Silver J. Formation of the retinal ganglion cell and optic fiber layers. J. Neurobiol. 22 (1991) 85-96
44. Weibel D., Cadelli D., and Schwab M.E. Regeneration of lesioned rat optic nerve fibers is improved after neutralization of myelin-associated neurite growth inhibitors. Brain Res. 642 1-2 (1994) 259-266
45. Wu H.H., Ivkovic S., and Murray R.C. Autoregulation of neurogenesis by GDF11. Neuron 37 (2003) 197-207
46. Zinovyeva M.V., Zijlmans J.M., Fibbe W.E., Visser J.W., and Belyavsky A.V. Analysis of gene expression in subpopulations of murine hematopoietic stem and progenitor cells. Exp. Hematol. 28 3 (2000) 318-334