Adaptation to chronic hypoxia during diet-induced ketosis

Advances in Experimental Medicine and Biology

Volumn 566, Issue , 2005, Pages 51-57

  Puchowicz, Michelle A ^a   Emancipator, Douglas S ^a   Xu, Kui ^a   Magness, Danielle L ^a   Ndubuizu, Obinna I ^a   Lust, W David ^a   LaManna, Joseph C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; KETONE; LACTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BODY WEIGHT; CARBOHYDRATE DIET; CONFERENCE PAPER; CONTROLLED STUDY; DIETARY INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HYPOBARISM; HYPOXIA; KETOACIDOSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CHRONIC DISEASE; DIET; GLUCOSE; GLYCOLYSIS; HYPOXIA, BRAIN; KETOSIS; LACTIC ACID; MALE; RATS; RATS, WISTAR;

RATTUS NORVEGICUS;

EID: 33646863907     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/0-387-26206-7_8     Document Type: Conference Paper

References (16)

1. S. I. Harik, R. A. Behmand, and J. C, LaManna, Hypoxia increases glucose transport at blood-brain barrier in rats, J. Appl. Physiol. 77, 896-901 (1994).
2. S. I. Harik, W. D. Lust, S. C. Jones, K. L. Lauro, S. Pundik, and J. C. LaManna, Brain glucose metabolism in hypobaric hypoxia, J. Appl. Physiol. 79, 136-140 (1995).
3. J. C. LaManna, Hypoxia/ischemia and the pH paradox, Adv. Exp. Med. Biol. 388, 283-292 (1996).
4. O. E. Owen, A. P. Morgan, H. G. Kemp, J. M. Sullivan, M. G. Herrera, and G. F. Cahill Jr., Brain metabolism during fasting, J. Clin. Invest. 46, 1589-1595 (1967).
5. L. Sokoloff, Metabolism of ketone bodies by the brain, Ann. Rev. Med. 24, 271-280 (1973).
6. M. C. McKenna, J. T. Tildon, J. H. Stevenson, R. Boatright, and S. Huang, Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: differences revealed using aminooxyacetate, Develop. Neurosci. 15, 320-329 (1993).
7. J. M. Freeman, M. T. Kelly, and J. B. Freeman, The Epilepsy Diet Treatment, 2nd edition (Demos Vermande, New York, 1996).
8. G. F. J. Cahill, and O. E. Owen, Starvation and survival, Trans. Am. Clin. Climat. Ass. 79, 13-18 (1967).
9. N. B. Ruderman, P. S. Ross, M. Berger, and M. N. Goodman, Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats, Biochem. J. 138, 1-10 (1974).
10. S. I. Harik, A. S. Al-Mudallal, J. C. LaManna, W. D. Lust, and B. E. Levin, Ketogenic diet and the brain, Ann. NY Acad Sci. 835, 218-224 (1997).
11. J. C. LaManna, K. A. McCracken, and K. P. Strohl, Changes in regional cerebral blood flow and sucrose space after 3-4 weeks of hypobaric hypoxia (0.5 ATM), Adv. Exp. Med. Biol. 248, 471-477 (1989).
12. J. C. LaManna, L. M. Vendel, and R. M. Farrell, Brain adaptation to chronic hypobaric hypoxia in rats, J. Appl. Physiol. 72, 2238-2243 (1992).
13. U. Ponten, R. A. Ratcheson, L. G. Salford, and B. K. Siesjo, Optimal freezing conditions for cerebral metabolites in rats, J. Neurochem. 21, 1127-1138 (1973).
14. S. G. Hasselbalch, G. M. Knudsen, J. Jakobsen, L. P. Hageman, S. Holm, and O. B. Paulson, Blood-brain barrier permeability of glucose and ketone bodies during short-term starvation in humans, Am. J. Physiol. 268, E1161-E1166 (1995).
15. D. Z. Gerhart, B. E. Enerson, O. Y. Zhdankina, R. L. Leino, and L. R. Drewes, Expression of the monocarboxylate transporter MCT2 by rat brain glia, Glia 22, 272-281 (1998).
16. J. W. Pan, T. L. Rothman, K. L. Behar, D. T. Stein, and H. P. Hetherington, Human brain beta-hydroxybutyrate and lactate increase in fasting-induced ketosis, J. Cereb. Blood Flow Metab. 20(10), 1502-1507