Influence of a proton gradient on the transport kinetics of the H+/amino acid cotransporter PAT1 in Caco-2 cells

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 63, Issue 3, 2006, Pages 360-364

  Metzner, Linda ^a   Brandsch, Matthias ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Caco 2 cells; DEPC; Drug delivery; H+ amino acid cotransporter; Histidyl residues; Proton gradient

Indexed keywords

4 AMINOBUTYRIC ACID DERIVATIVE; ALLOHYDROXYPROLINE; AMINO ACID TRANSPORTER; AZETIDINE 2 CARBOXYLIC ACID; CYCLOSERINE; DIETHYL PYROCARBONATE; HISTIDINE DERIVATIVE; HOMOTAURINE; NIPECOTIC ACID; PROLINE; PROLINE DERIVATIVE; PROTEIN PAT1; PROTON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; DRUG UPTAKE; INTESTINE CELL; MOLECULAR CLONING; NONHUMAN; PH MEASUREMENT; VELOCITY;

AMINO ACID TRANSPORT SYSTEMS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CATALYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; PROLINE; SYMPORTERS;

EID: 33646853892     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.01.009     Document Type: Article

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