Attenuation of restraint induced behavioral deficits by buspirone and propranolol in rats

Journal of the College of Physicians and Surgeons Pakistan

Volumn 15, Issue 12, 2005, Pages 795-798

  Samad, Noreen ^a   Parveen, Tahira ^a   Haider, Saida ^a   Haleem, Darakhshan Jabeen ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

5 HT1A receptors; Behavioral deficits; Buspirone; Learned helplessness; Propranolol; Somatodendritic; Stress

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUSPIRONE; PROPRANOLOL; SEROTONIN AGONIST;

ANIMAL; ANIMAL BEHAVIOR; ARTICLE; DRUG ADMINISTRATION; DRUG EFFECT; EXERCISE; MALE; RAT; WISTAR RAT;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BEHAVIOR, ANIMAL; BUSPIRONE; DRUG ADMINISTRATION SCHEDULE; MALE; PROPRANOLOL; RATS; RATS, WISTAR; RESTRAINT, PHYSICAL; SEROTONIN AGONISTS;

EID: 33646852859     PISSN: 1022386X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Kennett GA, Curzon G. Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors: hypophagia induced by RU24969 only required 5-HT1B receptors. Psychopharmacology (Berl) 1988; 96: 93-100.
2. Haleem DJ, Kennett G, Curzon G. Adaptation of female rats to stress: shift to male pattern by inhibition of corticosterone synthesis. Brain Res 1988; 458: 339-47.
3. Weiss JM, Goodman PA, Nositi BG, Corrigan S, Charry JM, Bailey WH. Behavioral depression produced by uncontrollable stressor: relationship to norepinephrine, dopamine and serotonin levels in various regions of rat brain. Brain Res Rev 1986; 3: 167-75.
4. Haleem DJ, Parveen T. Brain regional serotonin synthesis following adaptation to repeated restraint. Neuro Report 1994; 5: 1785-8.
5. Samad N, Parveen T, Haider S, Haleem DJ. Effect of repeated injection of neem leaf extract and restraint stress on a model of anxiety and brain serotonin metabolism in rats. J Hamdard Medicus 2002; 45: 54-8.
6. Haleem DJ. Serotonergic mechanism of anti-depressant action and adaptation to stress. J Coll Physicians Surg Pak 1999; 9: 139-46.
7. Haleem DJ, Saify ZS, Siddiqui S, Batool F, Haleem MA. Pre- and postsynaptic receptors to 1-(1-nepthyl piperazine) following adaptation to stress in rats. Prog Neuropsychopharmacol Biol Psychiatry 2002; 26: 146-56.
8. Invernizzi R, Carli M, Di Clemente A, Samanin R. Administration of 8-OH-DPAT in raphe nuclei dorsalis and madianus reduces serotonin synthesis in the rat brain: differences in potency and regional sensitivity. J Neurochem 1991; 56: 243-7.
9. O'Connell MT, Curzon G. A comparison of the effects of 8-OH-DPAT pre-treatment of differential behavioral responses to 8-OH-DPAT. Eur J Pharmacol 1996; 312: 137-43.
10. Johnson BA. Role of the serotonergic system in the neurobiology of alcoholism: implications of treatment. CNS Drugs 2004; 18: 1105-18.
11. Smith LM, Peroutka SJ. Differential effects of 5-hydroxytryptamine 1A drugs on the 5-HT behavioral syndrome. Pharmacol Biochem Behav 1986; 24: 1313-9.
12. Blier P, de Montigny C. Modification of 5-HT neurons properties by sustained administration of the 5-HT 1A agonist gepirone: electrophysiological studies in the rat brain. Synapse 1987; 1: 470-80.
13. Okazawa H, Yamane F, Blier P, Diksic M. Effect of acute and chronic administration of the serotonin-1A agonist buspirone on serotonin synthesis in rat brain. J Neurochem 1999; 72: 2022-31.
14. Haller J, Halasz J, Majercsik E. Psychosocial conditions and the efficacy of clinically available anxiolytics. Curr Drug Targets 2004; 5: 655-64.
15. Khouzam HR, Emes R. The use of buspirone in primary care. J Psychosoc Nurs Ment Health Serv 2002; 40: 34-41.
16. Blier P, Ward NM. Is there a role for 5-HT (1A) agonists in the treatment of depression? Biol Pshychiatry 2003; 53: 193-203.
17. VanderMaelen CP, Matheson GK, Wilderman RC, Patterson LA. Inhibition of serotonergic dorsal rapheneurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug. Eur J Pharmacol 1986; 129: 123-30.
18. Sprouse JS, Aghajanian GK. Electrophysiological responses of serotonergic dorsal rapheneurons to 5-HT1A and 5-HT1B agonists. Synapse 1987; 1: 3-9.
19. Blier P, de Montigny C. Differential effects of gepirone on pre-synaptic and postsynaptic serotonin receptors: single cell recording studies. J Clin Psychopharmacol 1990; 10(supp 3): 13S-20S.
20. Glieter CH, Deckert J. Adverse CNS effect of beta-adrenoceptor blockers. Pharmacopshchiatry 1996; 29: 201-11.
21. Kumar A, Shahani BT, Gulati A. Modification of systemic and regional circulatory effect of intracerebroventricular administration of endothelin-1 by propranolol in anesthetized rats. Gen Pharmacol 1996; 27: 1025-33.
22. Noyes R Jr. Beta adrenergic blocking drugs in anxiety and stress. Psychiatr Clin North Am 1985; 8: 119-32.
23. Ossowska G, Zebrowska-Lupina I, Danilczuk Z, Klenk-Majewska B. Repeated treatment with selective serotonin re-uptake inhibitors but not anxiolytics prevents the stress-induced deficits of fighting behavior. Pol J Pharmacol 2002; 54: 373-80.
24. Ju CY, Tsai CT. Serotonergic mechanism involved in the suppression of feeding by 5-HTP in rats. Chin J Physiol 1995; 38: 235-40.
25. Shimada T, Matsumoto K, Osanai M, Matsuda H, Terasawa K, Watanabe H. The modified light/dark transition test in mice: evaluation of classic and putative anxiolytic and anxiogenic drugs. Gen Pharmacol 1995; 26: 205-10.
26. Young R, Johnson DN. Comparison of routes of administration and time course effect of zacopride and buspirone in mice using an automated light-dark test. Pharmacol Biochem Biobehav 1991; 40: 733-7.
27. Gilbert F, Dourish CT. Effect of the novel anxiolytic gepirone, buspirone and ipsapirone on free feeding and on feeding induced by 8-OH-DPAT. Psychopharmacology (Berl) 1987; 93: 349-54.
28. Tunnicliff G, Brokaw JJ, Hausz JA, Metheson GK, White GW. Influence of repeated treatment with buspirone on 5-hydroxytryptamine and dopamine synthesis. Neuropharmacology 1992; 31: 991-5.
29. Sprouse JS, Aghajanian GK. (-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT 1A selective agonists. Eur J Pharmacol 1986; 128: 295-8.
30. Prisco S, Cagnotto A, Talone D, De Blasi A, Mennini T, Esposito E. Tertatolol a new b-blocker is a serotonin (5-hydroxytryptamine 1A) receptor antagonist in rat brain. J Pharmacol Exp Thr 1993; 265: 739-44.
31. D'Arbe M, Einstien R, Lavidas NA. Stressful animals housing conditions and their potential effect on sympathetic neurotransmission in mice. Am J Physiol Regular Integr Comp Physiol 2002; 282: 1422-8.
32. Pineyro G, Blier P. Autoregulation of serotonin neurons: role in antidepressant drugs action. Pharmacol Rev 1999; 51: 533-91.
33. Taylor F, Cahill L. Propranolol for re-emergent posttraumatic stress disorder following an event of retraumatization: a case study. J Trauma Stress 2002; 15: 433-7.
34. Dyck JB, Chung F. A comparision of propranolol and diazepam for pre-operative anxiolysis. Can J Anaesth 1991; 38: 704-9.
35. Mealy K, Ngeh N, Gillen P, Fitzpatrick G, Keane FB, Tanner A. Propranolol reduces the anxiety associated with day case surgery. Eur J Surg 1996; 162: 11-4.