Effects of growth hormone treatment on neutrophil count in children born small for gestational age [26]

Pediatrics

Volumn 117, Issue 5, 2006, Pages 1868-1869

  Ibáñez, Lourdes ^a   Ong, Ken ^b,c   Dunger, David B ^c   De Zegher, Francis ^d  

^a UNIVERSITY OF BARCELONA   (Spain)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; METFORMIN; ANTIDIABETIC AGENT; HUMAN GROWTH HORMONE;

CLINICAL TRIAL; DRUG EFFECT; GESTATIONAL AGE; HUMAN; HYPERANDROGENISM; HYPERINSULINEMIA; LETTER; LOW BIRTH WEIGHT; META ANALYSIS; NEUTROPHIL COUNT; PRECOCIOUS PUBERTY; PRIORITY JOURNAL; SHORT STATURE; SYSTEMATIC REVIEW; CHILD; GROWTH DISORDER; LEUKOCYTE COUNT; NEUTROPHIL; NEWBORN; SMALL FOR DATE INFANT;

CHILD; GROWTH DISORDERS; HUMAN GROWTH HORMONE; HUMANS; HYPOGLYCEMIC AGENTS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; LEUKOCYTE COUNT; METFORMIN; NEUTROPHILS; PUBERTY, PRECOCIOUS;

EID: 33646851034     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2006-0022     Document Type: Letter

References (9)

1. Ibáñez L, Fucci A, Valls C, Ong K, Dunger D, de Zegher F. Neutrophil count in small-for-gestational age children: contrasting effects of metformin and growth hormone therapy. J Clin Endocrinol Metab. 2005;90:3435-3439
2. Ibáñez L, Jaramillo AM, Ferrer A, de Zegher F. High neutrophil count in girls and women with hyperinsulinaemic hyperandrogenism: normalization with metformin and flutamide overcomes the aggravation by oral contraception. Hum Reprod. 2005;20:2457-2462
3. Ibáñez L, Valls C, Ong K, Dunger D, de Zegher F. Metformin therapy during puberty delays menarche, prolongs pubertal growth, and augments adult height: a randomized study in low-birthweight girls with early-normal onset of puberty. J Clin Endocrinol Metab. 2006; In press
4. Ibáñez L, Ong K, Dunger D, de Zegher F. Early development of adiposity and insulin resistance following catch-up weight gain in small-for-gestational-age children. J Clin Endocrinol Metab. 2006; In press
5. Orio F Jr, Palomba S, Cascella T, et al. The increase of leukocytes as a new putative marker of low-grade chronic inflammation and early cardiovascular risk in polycystic ovary syndrome. J Clin Endocrinol Metab. 2005;90(1):2-5
6. Puder JJ, Varga S, Kraenzlin M, De Geyter C, Keller U, Muller B. Central fat excess in polycystic ovary syndrome: relation to low-grade inflammation and insulin resistance. J Clin Endocrinol Metab. 2005;90:6014-6021
7. Sohmiya M, Kanazawa I, Kato Y. Effect of recombinant human GH on circulating granulocyte colony-stimulating factor and neutrophils in patients with adult GH deficiency. Eur J Endocrinol. 2005;152:211-215
8. de Zegher F, Hokken-Koelega A. Growth hormone therapy for children born small for gestational age: height gain is less dose dependent over the long term than over the short term. Pediatrics. 2005;115(4). Available at: www.pediatrics.org/cgi/content/full/115/4/e458
9. Ibáñez L, Valls C, Marcos MV, Ong K, Dunger D, de Zegher F. Insulin sensitization for girls with precocious pubarche and with risk for polycystic ovary syndrome: effects of prepubertal initiation and postpubertal discontinuation of metformin. J Clin Endocrinol Metab. 2004;89:4331-4337