Lithium response and Val66Met polymorphism of the brain-derived neurotrophic factor gene in Japanese patients with bipolar disorder

Psychiatric Genetics

Volumn 16, Issue 2, 2006, Pages 49-50

  Masui, Takuya ^a   Hashimoto, Ryota ^b   Kusumi, Ichiro ^a   Suzuki, Katsuji ^a   Tanaka, Teruaki ^a   Nakagawa, Shin ^a   Suzuki, Tatsuyo ^c   Iwata, Nakao ^c   Ozaki, Norio ^d   Kato, Tadafumi ^e   Kunugi, Hiroshi ^b   Koyama, Tsukasa ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Bipolar disorder; Brain derived neurotrophic factor; Lithium; Single nucleotide polymorphism

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; LITHIUM CARBONATE; TRANQUILIZER;

ADULT; ARTICLE; BIPOLAR DISORDER; DRUG EFFICACY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STATISTICAL SIGNIFICANCE; ALLELE; AMINO ACID SUBSTITUTION; DRUG RESISTANCE; GENETICS; LETTER; MIDDLE AGED; PHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; AMINO ACID SUBSTITUTION; ANTIMANIC AGENTS; BIPOLAR DISORDER; BRAIN-DERIVED NEUROTROPHIC FACTOR; DRUG RESISTANCE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; JAPAN; LITHIUM CARBONATE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES;

EID: 33646846328     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ypg.0000180680.72922.57     Document Type: Article

References (4)

1. Hashimoto K, Shimizu E, Iyo M (2004). Critical role of brain-derived neurotrophic factor in mood disorders. Brain Res Brain Res Rev 45:104-114.
2. Kunugi H, Iijima Y, Tatsumi M, Yoshida M, Hashimoto R, Kato T, et al. (2004). No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study. Biol Psychiatry 56:376-378.
3. Masui T, Hashimoto R, Kusumi I, Suzuki K, Tanaka T, Nakagawa S, et al. (in press). A possible association between the -116C/G single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in bipolar disorder. Int J Neuropsychopharmacol [published online June 1-6].
4. Neves-Pereira M, Mundo E, Muglia P, King N, Macciardi F, Kennedy JL (2002). The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet 71:651-655.