Acute effects of cage cleaning at different frequencies on laboratory rat behaviour and welfare

Animal Welfare

Volumn 15, Issue 2, 2006, Pages 161-171

  Burn, Charlotte C ^a   Peters, A ^a   Mason, G J ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

Aggression; Animal welfare; Behaviour; Husbandry; Rats; Stress

Indexed keywords

AGGRESSION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL HEALTH; ANIMAL HOUSING; ANIMAL WELFARE; ARTICLE; AVERSIVE BEHAVIOR; CAGE; CLEANING; CONTROLLED STUDY; DOMINANCE BEHAVIOR; ENVIRONMENTAL ENRICHMENT; EXPERIMENTAL RAT; FEEDING BEHAVIOR; FREQUENCY ANALYSIS; HARDER GLAND; LACRIMATION; MALE; NONHUMAN; PHYSICAL STRESS; RAT; SPECIES DIFFERENCE;

ANIMALIA; RATTUS NORVEGICUS; RODENTIA;

EID: 33646842706     PISSN: 09627286     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Adams N and Boice R 1983 A longitudinal study of dominance in an outdoor colony of domestic rats. Journal of Comparative Psychology 97: 24-33
2. Barnett SA, Fox IA and Hocking WE 1982 Some social postures of five species of Rattus. Australion Journal of Zoology 30: 581-601
3. Bender R and Lange S 2001 Adjusting for multiple testing - when and how? Journal of Clinical Epidemiology 54: 343-349
4. Borrello P, D'Amore E, Di Virgilio A, Panzini G, Valeri M and Lorenzini RN 1998 The use of AGI as a method to measure microbial contamination in the cage microenvironment Animal Technology 49: 81-85
5. Broderson J, Lindsey J and Crawford J 1976 The role of environmental ammonia in respiratory mycoplasmosis of rats. American Journal of Pathology 85: 115-130
6. Buelke-Sam J, Sullivan PA, Kimmel CA and Nelson CJ 1984 Sex and strain differences in the developmental activity profile of the rat tested over clean vs home cage bedding. Developmental Psychobiology 17: 67-77
7. Bulla G 1999 Fancy Rats: A Complete Pet Owner's Manual. Barrons Educational Series Inc: New York, USA
8. Burn CC Unpublished Effects of Husbandry Manipulations and the Laboratory Environment on Rat Health and Welfare. DPhil Thesis, University of Oxford, Oxford, UK
9. Burn CC, Day MJ, Peters A and Mason GJ 2006 Long-term effects of cage-cleaning frequency and bedding type on laboratory rat health, welfare and handleability: a cross-laboratory study. Laboratory Animals: in press
10. Carissimi AS, Chaguri LCAA, Teixeira MA, Mori CMC, Macchione M, Sant' Anna ETG, Saidiva PHN, Souza NL and Merusse JBL 2000 Effects of two ventilation systems and bedding change frequency on cage environmental factors in rats (Rattus norvegicus). Animal Technology 51: 161-170
11. Clement JG 1994 Chromodacryorrhea in rats - absence following soman poisoning. Toxicology and Applied Pharmacology 124: 52-58
12. Dagg AI, Bell WL and Windsor DE 1971 Urine marking of cages and visual isolation as possible sources of error in behavioural studies of small mammals. Laboratory Animals 5: 163-167
13. De Villiers C, Seier JV and Bok E 2004 Cage enrichment: the rats decide. Some preliminary observations. 9th FELASA Symposium: Internationalization and Harmonization in Laboratory Animal Care and Use Issues. 14-17 June 2004. Nantes, France
14. Doerning B 1999 Effects of routine animal husbandry and experimental procedures on physiological parameters of rats. Workshop on Refinements in Toxicology Testing. 14 March 1999. Hosted by the Humane Society of the United States: New Orleans, USA
15. Duke J, Zammit T and Lawson D 2001 The effects of routine cage-cleaning on cardiovascular and behavioural parameters in male Sprague-Dawley rats. Contemporary Topics in Laboratory Animal Science 40: 17-20
16. Foulkes A 2004 Effects of Enrichment on Chromodoccryrhoea in Rats. MSc Thesis, University of Guelph, Ontario, Canada
17. Fox S 1997 The Guide to Owning a Rat. TFH Publications Inc: Neptune City, NJ, USA
18. Gattermann R and Weinandy R 1996 Time of day and stress response to different stressors in experimental animals. Part I: Golden hamster (Mesocricetus ouratus Waterhouse, 1839). Journal of Experimental Animal Science 38: 66-76
19. Gray S and Hurst JL 1995 The effect of cage cleaning on aggression within groups of male laboratory mice. Animal Behaviour 49: 821-826
20. Harkness JE and Ridgway MD 1980 Chromodacryorrhea in laboratory rats (Rattus norvegicus): etiologic considerations. Laboratory Animal Science 30: 841-844
21. Hepburn MJ, Little PJ, Gingras J and Kuhn CM 1997 Differential effects of naltrindole on morphine-induced tolerance and physical dependence in rats. Journal of Pharmacology and Experimental Therapeutics 281: 1350-1356
22. Home Office 1995 Code of Practice for the Housing and Care of Animals in Designated Breeding and Supplying Establishments. Animals (Scientific Procedures) Act 1986. HMSO: London, UK
23. Hugo J, Krijt J, Vokurka M and Janousek V 1987 Secretory response to light in rat Harderian gland: possible photoprotective role of Harderian porphyrin. General Physiology and Biophysics 6: 401-404
24. Ishii T, Yoshida K, Hasegawa M, Mizuno S, Okamoto M, Tajima M and Kurosawa T 1998 Invention of a forced-air-ventilated micro-isolation cage and rack system. Environment within cages: temperature and ammonia concentration. Applied Animal Behaviour Science 59: 115-123
25. Kerins CA, Carlson DS, McIntosh JE and Bellinger LL 2003 Meal pattern changes associated with temporomandibular joint inflammation/pain in rats; analgesic effects. Pharmacology Biochemistry and Behavior 75: 181-189
26. Komorowska J and Pisula W 2003 Does changing levels of stress affect the characteristics of grooming behavior in rats? International Joumal of Comparative Psychology 16: 237-246
27. Lore R and Flannelly KJ 1978 Habitat selection and burrow construction by wild Rattus norvegicus in a landfill. Journal of Comparative and Physiological Psychology 92: 888-896
28. Manser CE, Broom DM, Overend P and Morris TH 1998 Investigations into the preferences of laboratory rats for nestboxes and nesting materials. Laboratory Animals 32: 23-35
29. Mason G, Wilson D, Hampton C and Wurbel H 2004 Non-invasively assessing disturbance and stress in laboratory rats by scoring chromodacryorrhoea. Alternatives to Laboratory Animals 32: 153-159
30. Meany MJ and Stewart J 1981 A descriptive study of social development in the rat, Rattus norvegicus. Animal Behaviour 29: 34-45
31. Mulder JB 1975 Bedding preferences of pregnant laboratory-reared mice. Behavior Research Methods and Instrumentation 7: 21-22
32. Odynets A, Simonova O, Kozhuhov A, Zaitsev T, Verreva A, Gnilomedova L and Rudzish R 1991 Beddings for laboratory animals: criteria of biological evaluation. Laboratomye Zhyvotnye 1: 70-76
33. Panksepp J and Burgdorf J 2000 50-kHz chirping (laughter?) in response to conditioned and unconditioned tickle-induced reward in rats: effects of social housing and genetic variables. Behavioural Brain Research 115: 25-38
34. Patterson Kane EG 2003 Shelter enrichment for rats. Contemporary Topics in Laboratory Animal Science 42: 46-48
35. Pellis SM and Pellis VC 1987 Play-fighting differs from serious fighting in both target of attack and tactics of fighting in the laboratory rat Rattus norvegicus. Aggressive Behavior 13: 227-242
36. Pellis SM and Pellis VC 1992 juvenilized play fighting in subordinate male rats. Aggressive Behavior 18: 449-457
37. Pellis SM, Pellis VC and McKenna MM 1993 Some subordinates are more equal than others: play fighting amongst adult subordinate male rats. Aggressive Behavior 19: 385-393
38. Perkins SE and Lipman NS 1995 Characterization and quantification of microenvironmental contaminants in isolator cages with a variety of contact beddings. Contemporary Topics in Laboratory Animal Science 34: 93-98
39. Ras T, van de Ven M, Patterson-Kane E and Nelson K 2002 Rats' preferences for corn versus wood-based bedding and nesting materials. Laboratory Animals 36:420-426
40. Richardson R and Campbell BA 1988 Effects of home nest odors on black-white preference in the developing rat implications for developmental learning research. Behavioral and Neural Biology 50: 361-366
41. Rohde DS and Basbaum AI 1998 Activation of coeruleospinal noradrenergic inhibitory controls during withdrawal from morphine in the rat. Journal of Neuroscience 18:4393-4402
42. Saibaba P, Sales GD, Stodulski G and Hau J 1996 Behaviour of rats in their home cages: daytime variations and effects of routine husbandry procedures analysed by time sampling techniques. Laboratory Animals 30: 13-21
43. Schnecko A, Witte K and Lemmer B 1998 Effects of routine procedures on cardiovascular parameters of Sprague-Dawley rats in periods of activity and rest. Journal of Experimental Animal Science 38: 181-190
44. Schultz D 1972 The effects of novelty on laboratory rat digging behavior. Psychonomic Science 29: 303-304
45. Sharp J, Zammit T and Lawson D 2002a Stress-like responses to common procedures in rats: effect of the estrous cycle. Contemporary Topics in Laboratory Animal Science 41: 15-22
46. Sharp JL, Zammit TG, Azar TA and Lawson DM 2002b Stress-like responses to common procedures in male rats housed alone or with other rats. Contemporary Topics in Laboratory Animal Science 41: 8-14
47. Sharp J, Zammit T, Azar T and Lawson D 2003 Are 'by-stander' female Sprague-Dawley rats affected by experimental procedures? Contemporary Topics in Laboratory Animal Science 42: 19-27
48. Sherwin CM 1996 Preferences of laboratory mice for characteristics of soiling sites. Animal Welfare 5: 283-288
49. Singh A, Einstein R and Lavidis N 2001 Effects of restraint stress on responsiveness of atria and vas deferens in Sprague-Dawley rats. Journal of Autonomic Pharmacology 21: 255-261
50. Smith LK, Fantella SLN and Pellis SM 1999 Playful defensive responses in adult male rats depend on the status of the unfamiliar opponent. Aggressive Behavior 25: 141-152
51. Takahashi LK and Lore RK 1983 Play fighting and the development of agonistic behavior in male and female rats. Aggressive Behavior 9: 217-227
52. Toates F 1995 Stress: Conceptual and Biological Aspects. Wiley: Chichester, UK
53. Townsend P 1997 Use of in-cage shelters by laboratory rats. Animal Welfare 6: 95-103
54. Van Loo PLP, Kruitwagen CLJJ, Van Zutphen LFM, Koolhaas JM and Baumans V 2000 Modulation of aggression in male mice: influence of cage cleaning regime and scent marks. Animal Welfare 9: 281-295
55. Van Loo PLP, Van der Meer E, Kruitwagen CLJJ, Koolhaas JM, Van Zutphen LFM and Baumans V 2003 Strain-specific aggressive behavior of male mice submitted to different husbandry procedures. Aggressive Behavior 29: 69-80
56. Weinandy R and Gattermann R 1997 Time of day and stress response to different stressors in experimental animals. Part II: Mongolian gerbil (Meriones unguiculatus, Milne Edwards, 1867). Journal of Experimental Animal Science 38: 109-122