Treatment of childhood diffuse brain stem tumors: Comparison of results in different treatment modalities

Clinical and Translational Oncology

Volumn 8, Issue 1, 2006, Pages 45-49

  Aquino Gorayeb, Melissa M ^a,b   Aisen, Salim ^a   Nadalin, Wladimir ^a   Gorayeb, Rodrigo Panico ^a   Andrade Carvalho, Heloisa ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Portugal)

Author keywords

Brain stem tumors; Chemotherapy; Children; Hormone therapy; Radiotherapy

Indexed keywords

CARBOPLATIN; TAMOXIFEN; VINCRISTINE; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS;

ADOLESCENT; ARTICLE; BRAIN STEM TUMOR; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INTERMETHOD COMPARISON; MALE; OPTIMAL DRUG DOSE; PROGNOSIS; RADIATION DOSE; SURVIVAL RATE; SURVIVAL TIME; SYMPTOM; TREATMENT RESPONSE; ASTROCYTOMA; BRAZIL; COMPARATIVE STUDY; LIFE TABLE; MEGAVOLTAGE RADIOTHERAPY; MORTALITY; MULTIMODALITY CANCER THERAPY; PRESCHOOL CHILD; REMISSION; SALVAGE THERAPY; SURVIVAL; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS, HORMONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASTROCYTOMA; BRAIN STEM NEOPLASMS; BRAZIL; CARBOPLATIN; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; FEMALE; HUMANS; LIFE TABLES; MALE; PROGNOSIS; RADIOTHERAPY, HIGH-ENERGY; REMISSION INDUCTION; SALVAGE THERAPY; SURVIVAL ANALYSIS; TAMOXIFEN; TREATMENT OUTCOME; VINCRISTINE;

EID: 33646841499     PISSN: 1699048X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12094-006-0094-9     Document Type: Article

References (23)

1. Gurney JG, Davis S, Severson RK, et al. Trends in cancer incidence among children in U.S. Cancer. 1996, p. 552-41.
2. Barkovich AJ, Krischer J, Kun LE. Brain stem gliomas: A classification system based on magnetic resonance imaging. Pediatr Neurosurg. 1990;16:73-83.
3. Vandertop WP, Hoffman HJ, Drake JM, et al. Focal midbrain tumors in children. Neurosurgery. 1992;31:186-94.
4. Greenberger JS, Cassady JR, Levene MB. Radiation therapy of thalamic, midbrain, and brain stem gliomas. Radiology. 1977; 122:463-8.
5. Edwards MSB, Prados M. Current management of brain stem gliomas. Pediatr Neurosci. 1987;13:509-15.
6. Albright AL, Guthkelch AN, Packer RJ, et al. Prognostic factors in pediatric brain stem gliomas. J. Neurosurg. 1986;65:751-5.
7. Albright AL, Packer RJ, Zimmerman R, et al. MR scans may replace biopsy in the diagnosis of brain stem gliomas: A report from the Children's Cancer Group. Neurosurgery. 1993;53:1026-9.
8. Hibi T, Shitara N, Genka S, et al. Radiotherapy for pediatric brain stem glioma: Radiation dose, response, and survival. Neurosurgery. 1992;31:643-50.
9. Langmoen A, Lundar T, Storn-Mathisen I, et al. Management of pediatric brain stem gliomas. Childs Nerv Syst. 1991;7:13-5.
10. Mandell LR, Kadota R, Freeman C, et al. There is no role for hyperfractionated radiotherapy in the management of children with newly diagnosed diffuse intrinsic brain stem tumors: Results of a Pediatric Oncology Group phase III trial comparing conventional vs hyperfractionated radiotherapy. Int J Radiat Biol Phys. 1999;43:959-64.
11. Benesch M, Lackner H, Moser A, et al. Outcome and long-term side effects after synchronous radiochemotherapy for childhood brain stem gliomas. Pediatr Neurosurg. 2001;35:173-80.
12. Statistical Package for Social Science-Systat. Version 10.0 SPSS Inc; 2000.
13. Guiney MJ, Smith JG, Hughes P, et al. Contemporary management of adult and pediatric brain stem gliomas. Int. J Radiat Oncol Biol Phys. 1993;25:235-41.
14. Rubin G, Michowitz S, Horev G, et al. Pediatric brain stem gliomas: An update. Childs Nerv Syst. 1998;14:4-5.
15. Shrieve DC, Wara WM, Edwards MS, et al. Hyperfractionated radiation therapy for gliomas of the brain stem in children and in adults. Int. J Radiat Oncol Biol Phys. 1992;24:599-610.
16. Farmer JP, Montes JL, Freeman CR, et al. Brain stem Gliomas. A 10-year institutional review. Pediatr Neurosurg. 2001; 34:206-14.
17. Broniscer A, Leite CC, Lanchote VL, et al. Radiation therapy and high-dose TMX in the treatment of patients with brain stem gliomas: results of a Brazilian cooperative study. J Clin Oncol. 2000;18:1246-53.
18. Bouffet E, Raquin M, Doz F, et al. Radiotherapy followed by high dose busulfan and thiotepa: A prospective assessment of high dose chemotherapy in children with diffuse pontine glioma. Cancer. 2000;88:685-92.
19. Packer RJ, Prados M, Phillips P, et al. Treatment of children with newly diagnosed brain stem gliomas with intravenous recombinant beta-interferon and hyperfractionated radiation therapy: A childrens cancer group phase I/II study. Cancer. 1996; 77:2150-6.
20. Lashoford LS, Thiesse P, Jouvet A, et al. Temozolomide in malignant gliomas of childhood: A United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. J. Clin Oncol. 2002;20:4684-91.
21. Kuo DJ, Weiner HL, Wisoff J, et al. Temozolomide is active in childhood, progressive, unresectable, low-grade gliomas. J Pediatr Hematol Oncol 2005;25:372-8.
22. Verschuur AC, Grill J, Lelouch-Tubiana A, et al. Temozolomide in paediatric highgrade glioma: A key for combination therapy? Br J Cancer 2004;91:425-9.
23. Broniscer A, Iacono L, Chintagumpala M, et al., Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: Results of a multiinstitutional study (SJHG-98). Cancer. 2005;103:153-9.