Topical interferon-α2b and keloid treatment: A place for pretreatment? [8]

Plastic and Reconstructive Surgery

Volumn 117, Issue 5, 2006, Pages 1645-1646

  Potgieter, Anton ^a   Candy, Geoff ^a   Leong, Cheryl V ^a   Widgerow, Alan D ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; COLLAGEN; IMIQUIMOD; AMINOQUINOLINE DERIVATIVE; IMMUNOLOGICAL ADJUVANT; INTERFERON INDUCING AGENT;

ACTINIC KERATOSIS; BASAL CELL CARCINOMA; COLLAGEN SYNTHESIS; CONDYLOMA; DRUG EFFECT; DRUG EFFICACY; HUMAN; INFORMED CONSENT; KELOID; LETTER; OUTCOME ASSESSMENT; PREMEDICATION; PRIORITY JOURNAL; SURGEON; SURGICAL PATIENT; SUTURE REMOVAL; SUTURING METHOD; THERAPY EFFECT; TREATMENT OUTCOME; ADULT; EXTERNAL EAR; FEMALE; MALE; MULTIMODALITY CANCER THERAPY; PILOT STUDY; TOPICAL DRUG ADMINISTRATION;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, TOPICAL; ADULT; AMINOQUINOLINES; COMBINED MODALITY THERAPY; EAR, EXTERNAL; FEMALE; HUMANS; INTERFERON INDUCERS; KELOID; MALE; PILOT PROJECTS;

EID: 33646838585     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000208927.66623.2e     Document Type: Letter

References (5)

1. Berman, B., and Duncan, M. R. Short-term keloid treatment in vivo with human interferon-α2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan and collagenase production in vitro. J. Am. Acad. Dermatol. 21: 694, 1989.
2. Jimenez, S. A., Freundlich, B., and Rosenbloom, J. Selective inhibition of human diploid fibroblast collagen synthesis by interferons. J. Clin. Invest. 3: 1112, 1984.
3. Berman, B., and Flores, F. Recurrence in excised keloids treated with postoperative triamcinolone acetonide injections or interferon-α2b injections. J. Am. Acad. Dermatol. 37: 755, 1997.
4. Berman, B., and Bieley, H. C. Adjuvant therapies to surgical management of keloids. Dermatol. Surg. 22: 126, 1996.
5. Berman, B., and Bieley, H. C. Keloids. J. Am. Acad. Dermatol. 33: 117, 1995.