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Volumn 27, Issue 6, 2005, Pages 718-721

Gender aspects of pharmacokinetics of new and old AEDs: Pregnancy and breast-feeding

Author keywords

Antiepileptic drugs; Breast milk; Epilepsy; Pharmacokinetics; Pregnancy

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETHOSUXIMIDE; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; PRIMIDONE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

EID: 33646837183     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ftd.0000179843.63515.8f     Document Type: Conference Paper
Times cited : (58)

References (32)
  • 1
    • 5344272596 scopus 로고    scopus 로고
    • Navigating toward fetal and maternal health: The challenge of treating epilepsy in pregnancy
    • Tomson T, Battino D, Perucca E. Navigating toward fetal and maternal health: the challenge of treating epilepsy in pregnancy. Epilepsia. 2004;45:1171-1175.
    • (2004) Epilepsia , vol.45 , pp. 1171-1175
    • Tomson, T.1    Battino, D.2    Perucca, E.3
  • 2
    • 0034044555 scopus 로고    scopus 로고
    • Anticonvulsant use during lactation
    • Hägg S, Spigset O. Anticonvulsant use during lactation. Drug Saf. 2000;22:425-440.
    • (2000) Drug Saf , vol.22 , pp. 425-440
    • Hägg, S.1    Spigset, O.2
  • 3
    • 0023267128 scopus 로고
    • Drug metabolism in pregnancy, infancy and childhood
    • Perucca E. Drug metabolism in pregnancy, infancy and childhood. Pharmacol Ther. 1987;34:129-143.
    • (1987) Pharmacol Ther , vol.34 , pp. 129-143
    • Perucca, E.1
  • 4
    • 0141542598 scopus 로고    scopus 로고
    • Antiepileptic drug pharmacokinetics during pregnancy and lactation
    • Pennell PB. Antiepileptic drug pharmacokinetics during pregnancy and lactation. Neurology. 2003;61(Suppl 2):S35-S42.
    • (2003) Neurology , vol.61 , Issue.2 SUPPL.
    • Pennell, P.B.1
  • 5
    • 0026843468 scopus 로고
    • Antiepileptic drug disposition during pregnancy
    • Yerby MS,Friel PN. McCormick K. Antiepileptic drug disposition during pregnancy. Neurology. 1992;42(Suppl 5):12-16.
    • (1992) Neurology , vol.42 , Issue.5 SUPPL. , pp. 12-16
    • Yerby, M.S.1    Friel, P.N.2    McCormick, K.3
  • 6
    • 0021368474 scopus 로고
    • Changes in primidone/phenobarbital ratio during pregnancy and the puerperium
    • Battino D, Binelli S, Bossi L, et al. Changes in primidone/phenobarbital ratio during pregnancy and the puerperium. Clin Pharmacokinet. 1984;9:252-260.
    • (1984) Clin Pharmacokinet , vol.9 , pp. 252-260
    • Battino, D.1    Binelli, S.2    Bossi, L.3
  • 7
    • 0028299243 scopus 로고
    • Epilepsy and pregnancy: A prospective study of seizure control in relation to free and total plasma concentrations of carbamazepine and phenytoin
    • Tomson T, Lindbom U, Ekqvist B, et al. Epilepsy and pregnancy: a prospective study of seizure control in relation to free and total plasma concentrations of carbamazepine and phenytoin. Epilepsia. 1994;35:122-130.
    • (1994) Epilepsia , vol.35 , pp. 122-130
    • Tomson, T.1    Lindbom, U.2    Ekqvist, B.3
  • 8
    • 0030881934 scopus 로고    scopus 로고
    • Lamotrigine in pregnancy and lactation: A case report
    • Tomson T, Öhman I, Vitols S. Lamotrigine in pregnancy and lactation: a case report. Epilepsia. 1997;38:1039-1041.
    • (1997) Epilepsia , vol.38 , pp. 1039-1041
    • Tomson, T.1    Öhman, I.2    Vitols, S.3
  • 9
    • 0034041253 scopus 로고    scopus 로고
    • Lamotrigine in pregnancy: Pharmacokinetics during delivery, in the neonate, and during lactation
    • Öhman I, Vitols S, Tomson T. Lamotrigine in pregnancy: pharmacokinetics during delivery, in the neonate, and during lactation. Epilepsia. 2000;41:709-713.
    • (2000) Epilepsia , vol.41 , pp. 709-713
    • Öhman, I.1    Vitols, S.2    Tomson, T.3
  • 10
    • 0037162365 scopus 로고    scopus 로고
    • Lamotrigine clearance during pregnancy
    • Tran TA, Leppik IE, Blesi K, et al. Lamotrigine clearance during pregnancy. Neurology. 2002;59:251-255.
    • (2002) Neurology , vol.59 , pp. 251-255
    • Tran, T.A.1    Leppik, I.E.2    Blesi, K.3
  • 11
    • 0842282467 scopus 로고    scopus 로고
    • The impact of pregnancy and childbirth on the metabolism of lamotrigine
    • Pennell PB, Newport DJ, Stowe ZN, et al. The impact of pregnancy and childbirth on the metabolism of lamotrigine. Neurology. 2004;62:292-295.
    • (2004) Neurology , vol.62 , pp. 292-295
    • Pennell, P.B.1    Newport, D.J.2    Stowe, Z.N.3
  • 12
    • 3543083352 scopus 로고    scopus 로고
    • Gestation-induced changes in lamotrigine pharmacokinetics: A monotherapy study
    • de Haan GJ, Edelbroek P, Segers J, et al. Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study. Neurology. 2004;63:571-573.
    • (2004) Neurology , vol.63 , pp. 571-573
    • De Haan, G.J.1    Edelbroek, P.2    Segers, J.3
  • 13
    • 33748699501 scopus 로고    scopus 로고
    • Defining fetal exposure to lamotrigine
    • Pennell PB, Ritchie JC, Newport DJ, et al. Defining fetal exposure to lamotrigine (abstract). Epilepsia. 2004;45(Suppl. 7):233.
    • (2004) Epilepsia , vol.45 , Issue.7 SUPPL. , pp. 233
    • Pennell, P.B.1    Ritchie, J.C.2    Newport, D.J.3
  • 14
    • 0031422928 scopus 로고    scopus 로고
    • Lamotrigine: Pharmacokinetics
    • Garnett WR. Lamotrigine: pharmacokinetics. J Child Neurol. 1997;12 (Suppl 1):S10-S15.
    • (1997) J Child Neurol , vol.12 , Issue.1 SUPPL.
    • Garnett, W.R.1
  • 16
    • 0020401577 scopus 로고
    • Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics
    • Nau H, Kuhnz W, Egger HJ, et al. Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics. Clin Pharmacokinet. 1982;7:508-543.
    • (1982) Clin Pharmacokinet , vol.7 , pp. 508-543
    • Nau, H.1    Kuhnz, W.2    Egger, H.J.3
  • 17
    • 0025210032 scopus 로고
    • Pharmacokinetics of anticonvulsants in pregnancy: Alterations in plasma protein binding
    • Yerby MS, Friel PN, McCormick K, et al. Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding. Epilepsy Res. 1990;5:223-228.
    • (1990) Epilepsy Res , vol.5 , pp. 223-228
    • Yerby, M.S.1    Friel, P.N.2    McCormick, K.3
  • 18
    • 0028939634 scopus 로고
    • Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood
    • Pienimaki P, Hartikainen AL, Arvela P, et al. Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood. Epilepsia. 1995;36:241-248.
    • (1995) Epilepsia , vol.36 , pp. 241-248
    • Pienimaki, P.1    Hartikainen, A.L.2    Arvela, P.3
  • 19
    • 0037299332 scopus 로고    scopus 로고
    • Transplacental passage of lamotrigine in a human placenta perfusion system in vitro and in maternal cord blood in vivo
    • Myllynen PK, Pienimäki PK, Vähänkangas KH. Transplacental passage of lamotrigine in a human placenta perfusion system in vitro and in maternal cord blood in vivo. Eur J Clin Pharmacol. 2003;58:677-682.
    • (2003) Eur J Clin Pharmacol , vol.58 , pp. 677-682
    • Myllynen, P.K.1    Pienimäki, P.K.2    Vähänkangas, K.H.3
  • 20
    • 0023876833 scopus 로고
    • Pharmacokinetics of oxcarbazepine and 10-hydroxy-carbazepine in the newborn child of an oxcarbazepine-treated mother
    • Bulau P, Paar WD, von Unruh GE. Pharmacokinetics of oxcarbazepine and 10-hydroxy-carbazepine in the newborn child of an oxcarbazepine-treated mother. Eur J Clin Pharmacol. 1988;34:311-313.
    • (1988) Eur J Clin Pharmacol , vol.34 , pp. 311-313
    • Bulau, P.1    Paar, W.D.2    Von Unruh, G.E.3
  • 21
    • 0035207595 scopus 로고    scopus 로고
    • Transplacental passage of oxcarbazepine and its metabolites in vivo
    • Myllynen P, Pienimäki P, Jouppila P, et al. Transplacental passage of oxcarbazepine and its metabolites in vivo. Epilepsia. 2001;42:1482-1485.
    • (2001) Epilepsia , vol.42 , pp. 1482-1485
    • Myllynen, P.1    Pienimäki, P.2    Jouppila, P.3
  • 22
    • 0036799782 scopus 로고    scopus 로고
    • Topiramate kinetics during delivery, lactation, and in the neonate: Preliminary observations
    • Öhman I, Vitols S, Luef G, et al. Topiramate kinetics during delivery, lactation, and in the neonate: preliminary observations. Epilepsia. 2002;43:1157-1160.
    • (2002) Epilepsia , vol.43 , pp. 1157-1160
    • Öhman, I.1    Vitols, S.2    Luef, G.3
  • 23
    • 0036119946 scopus 로고    scopus 로고
    • Pharmacokinetics of zonisamide in perinatal period
    • Kawada K, Itoh S, Kusaka T, et al. Pharmacokinetics of zonisamide in perinatal period. Brain Dev. 2002;24:95-97.
    • (2002) Brain Dev , vol.24 , pp. 95-97
    • Kawada, K.1    Itoh, S.2    Kusaka, T.3
  • 24
    • 18244369989 scopus 로고    scopus 로고
    • Levetiracetam concentrations in serum and in breast-milk at birth and during lactation
    • Johannessen SI, Helde G, Brodtkorb E. Levetiracetam concentrations in serum and in breast-milk at birth and during lactation. Epilepsia. 2005;46:1-3.
    • (2005) Epilepsia , vol.46 , pp. 1-3
    • Johannessen, S.I.1    Helde, G.2    Brodtkorb, E.3
  • 26
    • 0027402753 scopus 로고
    • A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of lack of proportionality between increasing dose and drug levels in plasma
    • Stewart BH, Kugler AR, Thompson PR, et al. A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of lack of proportionality between increasing dose and drug levels in plasma. Pharm Res. 1993;10:276-281.
    • (1993) Pharm Res , vol.10 , pp. 276-281
    • Stewart, B.H.1    Kugler, A.R.2    Thompson, P.R.3
  • 27
    • 0020401577 scopus 로고
    • Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics
    • Nau H, Kuhnz W, Egger HJ, et al. Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics. Clin Pharmacokinet. 1982;7:508-543.
    • (1982) Clin Pharmacokinet , vol.7 , pp. 508-543
    • Nau, H.1    Kuhnz, W.2    Egger, H.J.3
  • 28
    • 0021145288 scopus 로고
    • Valproic acid in breastmilk: How much is really there?
    • Von Unruh GE, Froescher W, Hoffmann F, et al. Valproic acid in breastmilk: how much is really there? Ther Drug Monit. 1984;6:272-276.
    • (1984) Ther Drug Monit , vol.6 , pp. 272-276
    • Von Unruh, G.E.1    Froescher, W.2    Hoffmann, F.3
  • 30
    • 0021748759 scopus 로고
    • Ethosuxumide in epileptic women during pregnancy and lactation period. Placental transfer, serum concentrations in nursed infants and clinical status
    • Kuhnz W, Koch S, Jakob S, et al. Ethosuxumide in epileptic women during pregnancy and lactation period. Placental transfer, serum concentrations in nursed infants and clinical status. Br J Clin Pharmacol. 1984;18:671-677.
    • (1984) Br J Clin Pharmacol , vol.18 , pp. 671-677
    • Kuhnz, W.1    Koch, S.2    Jakob, S.3
  • 31
    • 0023881871 scopus 로고
    • Primidone and phenobarbital during lactation period in epileptic women: Total and free drug serum levels in the nursed infants and their effects on neonatal behaviour
    • Kuhnz W, Koch S, Helge H, et al. Primidone and phenobarbital during lactation period in epileptic women: total and free drug serum levels in the nursed infants and their effects on neonatal behaviour. Dev Pharmacol Ther. 1988;11:147-154.
    • (1988) Dev Pharmacol Ther , vol.11 , pp. 147-154
    • Kuhnz, W.1    Koch, S.2    Helge, H.3
  • 32
    • 0032815294 scopus 로고    scopus 로고
    • Monitoring of zonisamide in human breast milk and maternal plasma by solid-phase extraction HPLC method
    • Shimoyama R, Ohkubo T, Sugawara K. Monitoring of zonisamide in human breast milk and maternal plasma by solid-phase extraction HPLC method. Biomed Chromatogr. 1999;13:370-372.
    • (1999) Biomed Chromatogr , vol.13 , pp. 370-372
    • Shimoyama, R.1    Ohkubo, T.2    Sugawara, K.3


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