Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal

Clinical Endocrinology

Volumn 64, Issue 6, 2006, Pages 659-666

  Prazeres, Hugo João ^a   Rodrigues, Fernando ^a   Figueiredo, Paulo ^a   Naidenov, Plamen ^a   Soares, Paula ^b   Bugalho, Maria João ^c   Lacerda, Manuela ^a   Campos, Beatriz ^a   Martins, Teresa C ^a  

^a Instituto Portugues de Oncologia Francisco Gentil Centro Regional de Oncologia de Coimbra SA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; PROTEIN RET; PROTEIN TYROSINE KINASE; TYROSINE;

ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; FAMILY; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; MULTIPLE ENDOCRINE NEOPLASIA; MUTATIONAL ANALYSIS; NEUROFIBROMATOSIS; POLYMERASE CHAIN REACTION; PORTUGAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTO ONCOGENE; RECURRENT DISEASE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; SIPPLE SYNDROME; STATISTICAL SIGNIFICANCE; THYROID MEDULLARY CARCINOMA;

ADULT; AGED; ANIMALS; BASE SEQUENCE; CARCINOMA, MEDULLARY; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A; MUTATION; PEDIGREE; PORTUGAL; PROTO-ONCOGENE PROTEINS C-RET; SEQUENCE ALIGNMENT; THYROID NEOPLASMS;

EID: 33646830149     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2006.02524.x     Document Type: Article

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