Quantitative analysis of liquid formulations using FT-Raman spectroscopy and HPLC. The case of diphenhydramine hydrochloride in Benadryl®

Journal of Pharmaceutical and Biomedical Analysis

Volumn 41, Issue 4, 2006, Pages 1406-1411

  Orkoula, M G ^a,b   Kontoyannis, C G ^a,b   Markopoulou, C K ^c   Koundourellis, J E ^c  

^a UNIVERSITY OF PATRAS   (Greece)

^b INSTITUTE OF CHEMICAL ENGINEERING SCIENCES   (Greece)

^c School of Pharmacy   (Greece)

Author keywords

Benadryl ; Diphenhydramine hydrochloride; HPLC; Liquid formulations; Quantitative analysis; Raman spectroscopy

Indexed keywords

DIPHENHYDRAMINE;

ARTICLE; DRUG DETERMINATION; DRUG FORMULATION; ELIXIR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAMAN SPECTROMETRY;

ANTI-ALLERGIC AGENTS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIPHENHYDRAMINE; SPECTRUM ANALYSIS, RAMAN;

EID: 33646824118     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.02.051     Document Type: Article

References (22)

1. Pelletier M.J. Appl. Spectrosc. 57 (2003) 20A-42A and references therein
2. Szostak R., and Mazurek S. J. Mol. Spectrosc. 704 (2004) 235-245
3. Choquette S., Chesler S., Duewer D., Wang S., and O'Haver T. Anal. Chem. 68 (1996) 3525-3533
4. Estienne F., Massart D., Zanier-Szydlowski N., and Marteau P. Anal. Chim. Acta 424 (2000) 185-201
5. Gilles J., Gilmor D., and Bonner Denton M. J. Raman Spectrosc. 30 (1999) 767-771
6. Qu J., and Shao L. Appl. Spectrosc. 55 (2001) 1414-1421
7. Berger A., Koo T., Itzkan I., Horowitz G., and Feld M. Appl. Opt. 38 (1999) 2916-2926
8. Qi D., and Berger A. Appl. Spectrosc. 58 (2004) 1165-1171
9. Sato-Berru R.Y., Medina-Valtierra J., Medina-Gutierrez C., and Frausto-Reyes C. Spectrochim. Acta Part A 60 (2004) 2225-2229
10. Alia J.M., Edwards H., and Kiernan B. Spectrochim. Acta Part A 60 (2004) 1533-1542
11. De Beer T.R.M., Vergot G.J., Baeyens W.R.G., Remon J.P., Vervaet C., and Verpoort F. Eur. J. Pharm. Sci. 23 (2004) 355-362
12. Ferrer I., Heine C., and Thurman E. Anal. Chem. 76 (2004) 1437-1444
13. DiGregorio D., and Sherma J. J. Liq. Chromatogr. R. T. 22 (1999) 1599-1606
14. Lau O., and Mok C. J. Chromatogr. A 693 (1995) 45-54
15. Shoukrallah I. Anal. Lett. 24 (1991) 2043-2058
16. Orkoula M., Konoyannis C., Markopoulou C., and Koundourellis J. Proceedings of 12th Panhellenic Pharmaceutical Congress (2005) PS039, pp. 1-6
17. http://www.sigmaaldrich.com/
18. Strommen D., and Nakamoto K. Laboratory Raman Spectroscopy (1984), J. Wiley, New York p. 71-74
19. USP 23, NF-18, United States Pharmacopeial Convention Inc., 1995, p. 533.
20. The European Agency for the Evaluation of Medical Products. ICH Topc Q2B Note for Guidance on Validation of Analytical Procedures: Methology GPMP/ICH/281/95, 1996.
21. Otto M. Statistics and Computer Application in Analytical Chemistry (1999), Willey-VCH, Weinheim, Germany pp. 178-184
22. Miller J.C., and Miller J.N. Statistics for Analytical Chemistry 4 (1986), Ellis Horwood, England pp. 57-59 and 96-107 (Chapter 3)