Valproic Acid Prevents Brain Injury in a Canine Model of Hypothermic Circulatory Arrest: A Promising New Approach to Neuroprotection During Cardiac Surgery

Annals of Thoracic Surgery

Volumn 81, Issue 6, 2006, Pages 2235-2242

  Williams, Jason A ^a   Barreiro, Christopher J ^a   Nwakanma, Lois U ^a   Lange, Mary S ^a   Kratz, Lisa E ^a   Blue, Mary E ^a   Berrong, Jennifer ^a   Patel, Nishant D ^a   Gott, Vincent L ^a   Troncoso, Juan C ^a   Johnston, Michael V ^a   Baumgartner, William A ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N ACETYLASPARTIC ACID; PLACEBO; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN NECROSIS; CEREBELLUM; CONTROLLED STUDY; DOG; ENTORHINAL CORTEX; HEART ARREST; HEART SURGERY; HIPPOCAMPUS; HISTOPATHOLOGY; HYPOTHERMIA; MASS SPECTROMETRY; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

ANIMALS; APOPTOSIS; ASPARTIC ACID; BEHAVIOR, ANIMAL; BIOLOGICAL MARKERS; BRAIN; BRAIN CHEMISTRY; BRAIN DAMAGE, CHRONIC; CARDIOPULMONARY BYPASS; CIRCULATORY ARREST, DEEP HYPOTHERMIA INDUCED; CONSCIOUSNESS DISORDERS; CRANIAL NERVE DISEASES; DOGS; DRUG EVALUATION, PRECLINICAL; HISTONE DEACETYLASES; HYPOXIA-ISCHEMIA, BRAIN; MALE; MOVEMENT DISORDERS; NECROSIS; NEUROPROTECTIVE AGENTS; SENSATION DISORDERS; SINGLE-BLIND METHOD; VALPROIC ACID;

EID: 33646822802     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2005.12.060     Document Type: Article

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