-
1
-
-
0026430348
-
Brain tumors. Part 1
-
Black PM. Brain tumors. Part 1. N. Engl. J. Med. 324(21), 1471-1476 (1991).
-
(1991)
N. Engl. J. Med.
, vol.324
, Issue.21
, pp. 1471-1476
-
-
Black, P.M.1
-
2
-
-
0026434030
-
Brain tumors. Part 2
-
Black PM. Brain tumors. Part 2. N. Engl. J. Med. 324(22), 1555-1564 (1991).
-
(1991)
N. Engl. J. Med.
, vol.324
, Issue.22
, pp. 1555-1564
-
-
Black, P.M.1
-
3
-
-
0027923776
-
Gene therapy
-
Mavilio F, Bordignon C. Gene therapy. Nature 362(6418), 284 (1993).
-
(1993)
Nature
, vol.362
, Issue.6418
, pp. 284
-
-
Mavilio, F.1
Bordignon, C.2
-
4
-
-
0028807727
-
T lymphocyte-directed gene therapy for ADA-SCID: Initial trial results after 4 years
-
Blaese RM, Culver KW, Miller AD et al. T lymphocyte-directed gene therapy for ADA-SCID: initial trial results after 4 years. Science 270(5235), 475-480 (1995).
-
(1995)
Science
, vol.270
, Issue.5235
, pp. 475-480
-
-
Blaese, R.M.1
Culver, K.W.2
Miller, A.D.3
-
5
-
-
0028875936
-
Transfer of genes to humans: Early lessons and obstacles to success
-
Crystal RG. Transfer of genes to humans: early lessons and obstacles to success. Science 270(5235), 404-410 (1995).
-
(1995)
Science
, vol.270
, Issue.5235
, pp. 404-410
-
-
Crystal, R.G.1
-
6
-
-
0030928619
-
Gene therapy - Promises, problems and prospects
-
Verma IM, Somia N. Gene therapy - promises, problems and prospects. Nature 389(6648), 239-242 (1997).
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
7
-
-
0028946357
-
Targeted vectors for gene therapy
-
Miller N, Vile R. Targeted vectors for gene therapy. FASEB J. 9(2), 190-199 (1995).
-
(1995)
FASEB J.
, vol.9
, Issue.2
, pp. 190-199
-
-
Miller, N.1
Vile, R.2
-
9
-
-
0035030198
-
Delivery systems intended for in vivo gene therapy of cancer: Targeting and replication competent viral vectors
-
Galanis E, Vile R, Russell SJ. Delivery systems intended for in vivo gene therapy of cancer: targeting and replication competent viral vectors. Crit. Rev. Oncol. Hematol. 38(3), 177-192 (2001).
-
(2001)
Crit. Rev. Oncol. Hematol.
, vol.38
, Issue.3
, pp. 177-192
-
-
Galanis, E.1
Vile, R.2
Russell, S.J.3
-
10
-
-
0032580348
-
Human gene therapy
-
Anderson WF. Human gene therapy. Nature 392(Suppl. 6679), 25-30 (1998).
-
(1998)
Nature
, vol.392
, Issue.6679 SUPPL.
, pp. 25-30
-
-
Anderson, W.F.1
-
11
-
-
0025864440
-
Experimental therapy of human glioma by means of a genetically engineered virus mutant
-
Martuza RL, Malick A, Markert JM et al. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science 252(5007), 854-856 (1991).
-
(1991)
Science
, vol.252
, Issue.5007
, pp. 854-856
-
-
Martuza, R.L.1
Malick, A.2
Markert, J.M.3
-
12
-
-
0346873921
-
Oncolytic viruses: Clinical applications as vectors for the treatment of malignant gliomas
-
Shah AC, Benos D, Gillespie GY et al. Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas. J. Neurooncol. 65(3), 203-226 (2003).
-
(2003)
J. Neurooncol.
, vol.65
, Issue.3
, pp. 203-226
-
-
Shah, A.C.1
Benos, D.2
Gillespie, G.Y.3
-
13
-
-
0031463632
-
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
-
Ram Z, Culver KW, Oshiro EM et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nature Med. 3(12), 1354-1361 (1997).
-
(1997)
Nature Med.
, vol.3
, Issue.12
, pp. 1354-1361
-
-
Ram, Z.1
Culver, K.W.2
Oshiro, E.M.3
-
14
-
-
0033588816
-
A Phase 1 2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
-
GLI328 European-Canadian Study Group
-
Shand N, Weber F, Mariani L et al. A Phase 1 2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum. Gene Ther. 10(14), 2325-2335 (1999).
-
(1999)
Hum. Gene Ther.
, vol.10
, Issue.14
, pp. 2325-2335
-
-
Shand, N.1
Weber, F.2
Mariani, L.3
-
15
-
-
0034694011
-
A Phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
-
Rainov NG. A Phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther. 11(17), 2389-2401 (2000).
-
(2000)
Hum. Gene Ther.
, vol.11
, Issue.17
, pp. 2389-2401
-
-
Rainov, N.G.1
-
16
-
-
8944253769
-
Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas
-
Goebel EA, Davidson BL, Zabner J et al. Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas. Ann. Otol. Rhinol. Laryngol. 105(7), 562-567 (1996).
-
(1996)
Ann. Otol. Rhinol. Laryngol.
, vol.105
, Issue.7
, pp. 562-567
-
-
Goebel, E.A.1
Davidson, B.L.2
Zabner, J.3
-
17
-
-
17444427673
-
Differential susceptibility of primary and established human glioma cells to adenovirus infection: Targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer
-
Miller CR, Buchsbaum DJ, Reynolds PN et al. Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer. Cancer Res. 58(24), 5738-5748 (1998).
-
(1998)
Cancer Res.
, vol.58
, Issue.24
, pp. 5738-5748
-
-
Miller, C.R.1
Buchsbaum, D.J.2
Reynolds, P.N.3
-
18
-
-
0033556093
-
Loss of adenoviral receptor expression in human bladder cancer cells: A potential impact on the efficacy of gene therapy
-
Li Y, Pong RC, Bergelson JM et al. Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy. Cancer Res. 59(2), 325-330 (1999).
-
(1999)
Cancer Res.
, vol.59
, Issue.2
, pp. 325-330
-
-
Li, Y.1
Pong, R.C.2
Bergelson, J.M.3
-
19
-
-
0033373328
-
Variability of adenovirus receptor density influences gene transfer efficiency and therapeutic response in head and neck cancer
-
Li D, Duan L, Freimuth P et al. Variability of adenovirus receptor density influences gene transfer efficiency and therapeutic response in head and neck cancer. Clin. Cancer Res. 5(12), 4175-4181 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, Issue.12
, pp. 4175-4181
-
-
Li, D.1
Duan, L.2
Freimuth, P.3
-
20
-
-
0032212265
-
The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures
-
Hemmi S, Geertsen R, Mezzacasa A et al. The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures. Hum. Gene Ther. 9(16), 2363-2373 (1998).
-
(1998)
Hum. Gene Ther.
, vol.9
, Issue.16
, pp. 2363-2373
-
-
Hemmi, S.1
Geertsen, R.2
Mezzacasa, A.3
-
21
-
-
0034039807
-
Dependence of efficient adenoviral gene delivery in malignant glioma cells on the expression levels of the coxsackievirus and adenovirus receptor
-
Asaoka K, Tada M, Sawamura Y et al. Dependence of efficient adenoviral gene delivery in malignant glioma cells on the expression levels of the coxsackievirus and adenovirus receptor. J. Neurosurg. 92(6), 1002-1008 (2000).
-
(2000)
J. Neurosurg.
, vol.92
, Issue.6
, pp. 1002-1008
-
-
Asaoka, K.1
Tada, M.2
Sawamura, Y.3
-
22
-
-
0034136802
-
Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors
-
Trask TW, Trask RP, Aguilar-Cordova E et al. Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol. Ther. 1(2), 195-203 (2000).
-
(2000)
Mol. Ther.
, vol.1
, Issue.2
, pp. 195-203
-
-
Trask, T.W.1
Trask, R.P.2
Aguilar-Cordova, E.3
-
23
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53 deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A et al. An adenovirus mutant that replicates selectively in p53 deficient human tumor cells. Science 274(5286), 373-376 (1996).
-
(1996)
Science
, vol.274
, Issue.5286
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
24
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX 015, an E1B 55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A Phase II trial
-
Nemunaitis J, Ganly I, Khuri F et al. Selective replication and oncolysis in p53 mutant tumors with ONYX 015, an E1B 55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a Phase II trial. Cancer Res. 60(22), 6359-6366 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.22
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
25
-
-
0030917202
-
ONYX 015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
-
Heise C, Sampson-Johannes A, Williams A et al. ONYX 015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nature Med. 3(6), 639-645 (1997).
-
(1997)
Nature Med.
, vol.3
, Issue.6
, pp. 639-645
-
-
Heise, C.1
Sampson-Johannes, A.2
Williams, A.3
-
26
-
-
0033831080
-
A controlled trial of intratumoral ONYX 015, a selectively-replicating adenovirus, in combination with cisplatin and 5 fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I et al. A controlled trial of intratumoral ONYX 015, a selectively-replicating adenovirus, in combination with cisplatin and 5 fluorouracil in patients with recurrent head and neck cancer. Nature Med. 6(8), 879-885 (2000).
-
(2000)
Nature Med.
, vol.6
, Issue.8
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
27
-
-
7044228126
-
A Phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX 015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting
-
Chiocca EA, Abbed KM, Tatter S et al. A Phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX 015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol. Ther. 10(5), 958-966 (2004).
-
(2004)
Mol. Ther.
, vol.10
, Issue.5
, pp. 958-966
-
-
Chiocca, E.A.1
Abbed, K.M.2
Tatter, S.3
-
28
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus 1 for the treatment of malignant gliomas
-
Mineta T, Rabkin SD, Yazaki T et al. Attenuated multi-mutated herpes simplex virus 1 for the treatment of malignant gliomas. Nature Med. 1(9), 938-943 (1995).
-
(1995)
Nature Med.
, vol.1
, Issue.9
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
-
29
-
-
0032789088
-
Attenuated, replication-competent herpes simplex virus type 1 mutant G207: Safety evaluation of intracerebral injection in nonhuman primates
-
Hunter WD, Martuza RL, Feigenbaum F et al. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates. J. Virol. 73(8), 6319-6326 (1999).
-
(1999)
J. Virol.
, vol.73
, Issue.8
, pp. 6319-6326
-
-
Hunter, W.D.1
Martuza, R.L.2
Feigenbaum, F.3
-
30
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a Phase I trial
-
Markert JM, Medlock MD, Rabkin SD et al. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a Phase I trial. Gene Ther. 7(10), 867-874 (2000).
-
(2000)
Gene Ther.
, vol.7
, Issue.10
, pp. 867-874
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
-
31
-
-
0028141887
-
The herpes simplex virus type 1 strain 17+ γ 34.5 deletion mutant 1716 is avirulent in SCID mice
-
Valyi-Nagy T, Fareed MU, O'Keefe JS et al. The herpes simplex virus type 1 strain 17+ γ 34.5 deletion mutant 1716 is avirulent in SCID mice. J. Gen. Virol. 75(Pt 8), 2059-2063 (1994).
-
(1994)
J. Gen. Virol.
, vol.75
, Issue.8 PART
, pp. 2059-2063
-
-
Valyi-Nagy, T.1
Fareed, M.U.2
O'Keefe, J.S.3
-
32
-
-
0029113725
-
Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant
-
Randazzo BP, Kesari S, Gesser RM et al. Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant. Virology 211(1), 94-101 (1995).
-
(1995)
Virology
, vol.211
, Issue.1
, pp. 94-101
-
-
Randazzo, B.P.1
Kesari, S.2
Gesser, R.M.3
-
33
-
-
0028892032
-
Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant
-
Kesari S, Randazzo BP, Valyi-Nagy T et al. Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. Lab. Invest. 73(5), 636-648 (1995).
-
(1995)
Lab. Invest.
, vol.73
, Issue.5
, pp. 636-648
-
-
Kesari, S.1
Randazzo, B.P.2
Valyi-Nagy, T.3
-
34
-
-
12944272092
-
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
-
Rampling R, Cruickshank G, Papanastassiou V et al. Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther. 7(10), 859-866 (2000).
-
(2000)
Gene Ther.
, vol.7
, Issue.10
, pp. 859-866
-
-
Rampling, R.1
Cruickshank, G.2
Papanastassiou, V.3
-
35
-
-
8844274068
-
HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: Safety data and long-term survival
-
Harrow S, Papanastassiou V, Harland J et al. HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival. Gene Ther. 11(22), 1648-1658 (2004).
-
(2004)
Gene Ther.
, vol.11
, Issue.22
, pp. 1648-1658
-
-
Harrow, S.1
Papanastassiou, V.2
Harland, J.3
-
36
-
-
85047699172
-
The potential for efficacy of the modified (ICP 34.5[-]) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: A proof of principle study
-
Papanastassiou V, Rampling R, Fraser M et al. The potential for efficacy of the modified (ICP 34.5[-]) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study. Gene Ther. 9(6), 398-406 (2002).
-
(2002)
Gene Ther.
, vol.9
, Issue.6
, pp. 398-406
-
-
Papanastassiou, V.1
Rampling, R.2
Fraser, M.3
-
37
-
-
23044450359
-
Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan
-
Tyminski E, Leroy S, Terada K et al. Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan. Cancer Res. 65(15), 6850-6857 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.15
, pp. 6850-6857
-
-
Tyminski, E.1
Leroy, S.2
Terada, K.3
-
38
-
-
30344448580
-
Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication
-
Aghi M, Rabkin S, Martuza RL. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. J. Natl Cancer Inst. 98(1), 38-50 (2006).
-
(2006)
J. Natl. Cancer Inst.
, vol.98
, Issue.1
, pp. 38-50
-
-
Aghi, M.1
Rabkin, S.2
Martuza, R.L.3
-
39
-
-
0032515141
-
Reovirus therapy of tumors with activated Ras pathway
-
Coffey MC, Strong JE, Forsyth PA et al. Reovirus therapy of tumors with activated Ras pathway. Science 282(5392), 1332-1334 (1998).
-
(1998)
Science
, vol.282
, Issue.5392
, pp. 1332-1334
-
-
Coffey, M.C.1
Strong, J.E.2
Forsyth, P.A.3
-
40
-
-
0035918857
-
Reovirus as an oncolytic agent against experimental human malignant gliomas
-
Wilcox ME, Yang W, Senger D et al. Reovirus as an oncolytic agent against experimental human malignant gliomas. J. Natl Cancer Inst. 93(12), 903-912 (2001).
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, Issue.12
, pp. 903-912
-
-
Wilcox, M.E.1
Yang, W.2
Senger, D.3
-
41
-
-
19944427873
-
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: Racine and nonhuman primates
-
Yang WQ, Lun X, Palmer CA et al. Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates. Clin. Cancer Res. 10(24), 8561-8576 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, Issue.24
, pp. 8561-8576
-
-
Yang, W.Q.1
Lun, X.2
Palmer, C.A.3
-
42
-
-
0036528167
-
Oncolytics Biotech releases REOLYSIN Phase I clinical trial results
-
Oncolytics Biotech releases REOLYSIN Phase I clinical trial results. Expert Rev. Anticancer Ther. 2(2), 139 (2002).
-
(2002)
Expert Rev. Anticancer Ther.
, vol.2
, Issue.2
, pp. 139
-
-
-
43
-
-
0026751242
-
Newcastle disease virus selectively kills human tumor cells
-
Reichard KW, Lorence RM, Cascino CJ et al. Newcastle disease virus selectively kills human tumor cells. J. Surg. Res. 52(5), 448-453 (1992).
-
(1992)
J. Surg. Res.
, vol.52
, Issue.5
, pp. 448-453
-
-
Reichard, K.W.1
Lorence, R.M.2
Cascino, C.J.3
-
44
-
-
0035935255
-
Newcastle disease virus therapy of human tumor xenografts: Antitumor effects of local or systemic administration
-
Phuangsab A, Lorence RM, Reichard KW et al. Newcastle disease virus therapy of human tumor xenografts: antitumor effects of local or systemic administration. Cancer Lett. 172(1), 27-36 (2001).
-
(2001)
Cancer Lett.
, vol.172
, Issue.1
, pp. 27-36
-
-
Phuangsab, A.1
Lorence, R.M.2
Reichard, K.W.3
-
45
-
-
0028081158
-
Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy
-
Lorence RM, Katubig BB, Reichard KW et al. Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy. Cancer Res. 54(23), 6017-6021 (1994).
-
(1994)
Cancer Res.
, vol.54
, Issue.23
, pp. 6017-6021
-
-
Lorence, R.M.1
Katubig, B.B.2
Reichard, K.W.3
-
46
-
-
0027980233
-
Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapy
-
Lorence RM, Reichard KW, Katubig BB et al. Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapy. J. Natl Cancer Inst. 86(16), 1228-1233 (1994).
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, Issue.16
, pp. 1228-1233
-
-
Lorence, R.M.1
Reichard, K.W.2
Katubig, B.B.3
-
47
-
-
0027144317
-
Attenuated veterinary virus vaccine for the treatment of cancer
-
Csatary LK, Eckhardt S, Bukosza I et al. Attenuated veterinary virus vaccine for the treatment of cancer. Cancer Detect. Prev. 17(6), 619-627 (1993).
-
(1993)
Cancer Detect. Prev.
, vol.17
, Issue.6
, pp. 619-627
-
-
Csatary, L.K.1
Eckhardt, S.2
Bukosza, I.3
-
48
-
-
0346458886
-
Overview of Phase I studies of intravenous administration of PV701, an oncolytic virus
-
Lorence RM, Pecora AL, Major PP et al. Overview of Phase I studies of intravenous administration of PV701, an oncolytic virus. Curr. Opin. Mol. Ther. 5(6), 618-624 (2003).
-
(2003)
Curr. Opin. Mol. Ther.
, vol.5
, Issue.6
, pp. 618-624
-
-
Lorence, R.M.1
Pecora, A.L.2
Major, P.P.3
-
49
-
-
0033526315
-
Use of Newcastle disease virus vaccine (MTH 68/H) in a patient with high-grade glioblastoma
-
Csatary LK, Bakacs T. Use of Newcastle disease virus vaccine (MTH 68/H) in a patient with high-grade glioblastoma. JAMA 281(17), 1588-1589 (1999).
-
(1999)
JAMA
, vol.281
, Issue.17
, pp. 1588-1589
-
-
Csatary, L.K.1
Bakacs, T.2
-
50
-
-
1842484851
-
MTH 68/H oncolytic viral treatment in human high-grade gliomas
-
Csatary LK, Gosztonyi G, Szeberenyi J et al. MTH 68/H oncolytic viral treatment in human high-grade gliomas. J. Neurooncol. 67(12), 83-93 (2004).
-
(2004)
J. Neurooncol.
, vol.67
, Issue.12
, pp. 83-93
-
-
Csatary, L.K.1
Gosztonyi, G.2
Szeberenyi, J.3
-
51
-
-
0031797971
-
Introduction of adhesive and costimulatory immune functions into tumor cells by infection with Newcastle disease virus
-
Haas C, Ertel C, Gerhards R, Schirrmacher V. Introduction of adhesive and costimulatory immune functions into tumor cells by infection with Newcastle disease virus. Int. J. Oncol. 13(6), 1105-1115 (1998).
-
(1998)
Int. J. Oncol.
, vol.13
, Issue.6
, pp. 1105-1115
-
-
Haas, C.1
Ertel, C.2
Gerhards, R.3
Schirrmacher, V.4
-
52
-
-
0037089478
-
Tumor immunity within the central nervous system stimulated by recombinant Listeria monocytogenes vaccination
-
Liau LM, Jensen ER, Kremen TJ et al. Tumor immunity within the central nervous system stimulated by recombinant Listeria monocytogenes vaccination. Cancer Res. 62(8), 2287-2293 (2002).
-
(2002)
Cancer Res.
, vol.62
, Issue.8
, pp. 2287-2293
-
-
Liau, L.M.1
Jensen, E.R.2
Kremen, T.J.3
-
53
-
-
11444268362
-
Cellular immunity and immunotherapy of brain tumors
-
Prins RM, Liau LM. Cellular immunity and immunotherapy of brain tumors. Front. Biosci. 9, 3124-3136 (2004).
-
(2004)
Front. Biosci.
, vol.9
, pp. 3124-3136
-
-
Prins, R.M.1
Liau, L.M.2
-
54
-
-
0031183754
-
Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma
-
Miyatake S, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma. Cancer Gene Ther. 4(4), 222-228 (1997).
-
(1997)
Cancer Gene Ther.
, vol.4
, Issue.4
, pp. 222-228
-
-
Miyatake, S.1
Martuza, R.L.2
Rabkin, S.D.3
-
55
-
-
0034050884
-
Engineered herpes simplex virus expressing IL 12 in the treatment of experimental murine brain tumors
-
Parker JN, Gillespie GY, Love CE et al. Engineered herpes simplex virus expressing IL 12 in the treatment of experimental murine brain tumors. Proc. Natl Acad. Sci. USA 97(5), 2208-2213 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.5
, pp. 2208-2213
-
-
Parker, J.N.1
Gillespie, G.Y.2
Love, C.E.3
-
56
-
-
0031963349
-
Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins
-
Andreansky S, He B, van Cott J et al. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Ther. 5(1), 121-130 (1998).
-
(1998)
Gene Ther.
, vol.5
, Issue.1
, pp. 121-130
-
-
Andreansky, S.1
He, B.2
Van Cott, J.3
-
57
-
-
85047700220
-
In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma
-
Liu Y, Ehtesham M, Samoto K et al. In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma. Cancer Gene Ther. 9(1), 9-15 (2002).
-
(2002)
Cancer Gene Ther.
, vol.9
, Issue.1
, pp. 9-15
-
-
Liu, Y.1
Ehtesham, M.2
Samoto, K.3
-
58
-
-
0033946488
-
Immune gene therapy of experimental mouse brain tumor with adenovirus-mediated gene transfer of murine interleukin 4
-
Yoshikawa K, Kajiwara K, Ideguchi M et al. Immune gene therapy of experimental mouse brain tumor with adenovirus-mediated gene transfer of murine interleukin 4. Cancer Immunol. Immunother. 49(1), 23-33 (2000).
-
(2000)
Cancer Immunol. Immunother.
, vol.49
, Issue.1
, pp. 23-33
-
-
Yoshikawa, K.1
Kajiwara, K.2
Ideguchi, M.3
-
59
-
-
4644311756
-
Transcriptional targeting of adenovirally delivered tumor necrosis factor α by temozolomide in experimental glioblastoma
-
Yamini B, Yu X, Gillespi.e., GY et al. Transcriptional targeting of adenovirally delivered tumor necrosis factor α by temozolomide in experimental glioblastoma. Cancer Res. 64(18), 6381-6384 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.18
, pp. 6381-6384
-
-
Yamini, B.1
Yu, X.2
Gillespie, G.Y.3
-
60
-
-
0035139013
-
Low-dose vaccinia virus-mediated cytokine gene therapy of glioma
-
Chen B, Timiryasova TM, Haghighat P et al. Low-dose vaccinia virus-mediated cytokine gene therapy of glioma. J. Immunother. 24(1), 46-57 (2001).
-
(2001)
J. Immunother.
, vol.24
, Issue.1
, pp. 46-57
-
-
Chen, B.1
Timiryasova, T.M.2
Haghighat, P.3
-
61
-
-
0242382624
-
Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways
-
Newton HB. Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways. Expert Rev. Anticancer Ther. 3(5), 595-614 (2003).
-
(2003)
Expert Rev. Anticancer Ther.
, vol.3
, Issue.5
, pp. 595-614
-
-
Newton, H.B.1
-
62
-
-
2442495498
-
Development of novel targeted therapies in the treatment of malignant glioma
-
Rich JN, Bigner DD. Development of novel targeted therapies in the treatment of malignant glioma. Nature Rev. Drug Discov. 3(5), 430-446 (2004).
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, Issue.5
, pp. 430-446
-
-
Rich, J.N.1
Bigner, D.D.2
-
63
-
-
0034987702
-
Malignant glioma: Genetics and biology of a grave matter
-
Maher EA, Furnari FB, Bachoo RM et al. Malignant glioma: genetics and biology of a grave matter. Genes Dev. 15(11), 1311-1333 (2001).
-
(2001)
Genes Dev.
, vol.15
, Issue.11
, pp. 1311-1333
-
-
Maher, E.A.1
Furnari, F.B.2
Bachoo, R.M.3
-
64
-
-
2942670180
-
PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
-
Ostman A. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine Growth Factor Rev. 15(4), 275-286 (2004).
-
(2004)
Cytokine Growth Factor Rev.
, vol.15
, Issue.4
, pp. 275-286
-
-
Ostman, A.1
-
65
-
-
0028911678
-
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop
-
Guha A, Dashner K, Black PM et al. Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int. J. Cancer 60(2), 168-173 (1995).
-
(1995)
Int. J. Cancer
, vol.60
, Issue.2
, pp. 168-173
-
-
Guha, A.1
Dashner, K.2
Black, P.M.3
-
66
-
-
1142287357
-
Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis
-
Newton HB. Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis. Expert Rev. Anticancer Ther. 4(1), 105-128 (2004).
-
(2004)
Expert Rev. Anticancer Ther.
, vol.4
, Issue.1
, pp. 105-128
-
-
Newton, H.B.1
-
67
-
-
0041307002
-
Analysis of gene expression in the normal and malignant cerebellum
-
Wechsler-Reya RJ. Analysis of gene expression in the normal and malignant cerebellum. Recent Prog. Horm. Res. 58, 227-248 (2003).
-
(2003)
Recent Prog. Horm. Res.
, vol.58
, pp. 227-248
-
-
Wechsler-Reya, R.J.1
-
69
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy SL, Tamayo P, Gaasenbeek M et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415(6870), 436-442 (2002).
-
(2002)
Nature
, vol.415
, Issue.6870
, pp. 436-442
-
-
Pomeroy, S.L.1
Tamayo, P.2
Gaasenbeek, M.3
-
70
-
-
4544285754
-
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice
-
Romer JT, Kimura H, Magdaleno S et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 6(3), 229-240 (2004).
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 229-240
-
-
Romer, J.T.1
Kimura, H.2
Magdaleno, S.3
-
71
-
-
0030070484
-
CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated
-
Ueki K, Ono Y, Henson JW et al. CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res. 56(1), 150-153 (1996).
-
(1996)
Cancer Res.
, vol.56
, Issue.1
, pp. 150-153
-
-
Ueki, K.1
Ono, Y.2
Henson, J.W.3
-
72
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces antiglioma effect in vivo
-
Fueyo J, Gomez-Manzano C, Alemany R et al. A mutant oncolytic adenovirus targeting the Rb pathway produces antiglioma effect in vivo. Oncogene 19(1), 2-12 (2000).
-
(2000)
Oncogene
, vol.19
, Issue.1
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
-
73
-
-
13444292787
-
Comparative effect of oncolytic adenoviruses with E1A 55 kDa or E1B 55 kDa deletions in malignant gliomas
-
Jiang H, Gomez-Manzano C, Alemany R et al. Comparative effect of oncolytic adenoviruses with E1A 55 kDa or E1B 55 kDa deletions in malignant gliomas. Neoplasia 7(1), 48-56 (2005).
-
(2005)
Neoplasia
, vol.7
, Issue.1
, pp. 48-56
-
-
Jiang, H.1
Gomez-Manzano, C.2
Alemany, R.3
-
74
-
-
31544439172
-
δ 24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan
-
Gomez-Manzano C, Alonso MM, Yung WK et al. δ 24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan. Clin. Cancer Res. 12(2), 556-562 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.2
, pp. 556-562
-
-
Gomez-Manzano, C.1
Alonso, M.M.2
Yung, W.K.3
-
75
-
-
20044388552
-
δ24 hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization
-
Conrad C, Miller CR, Ji Y et al. δ24 hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization. Cancer Gene Ther. 12(3), 284-294 (2005).
-
(2005)
Cancer Gene Ther.
, vol.12
, Issue.3
, pp. 284-294
-
-
Conrad, C.1
Miller, C.R.2
Ji, Y.3
-
76
-
-
4243175966
-
Infectious delivery of the 132 kb CDKN2A/CDKN2B genomic DNA region results in correctly spliced gene expression and growth suppression in glioma cells
-
Inoue R, Moghaddam KA, Ranasinghe M et al. Infectious delivery of the 132 kb CDKN2A/CDKN2B genomic DNA region results in correctly spliced gene expression and growth suppression in glioma cells. Gene Ther. 11(15), 1195-1204 (2004).
-
(2004)
Gene Ther.
, vol.11
, Issue.15
, pp. 1195-1204
-
-
Inoue, R.1
Moghaddam, K.A.2
Ranasinghe, M.3
-
77
-
-
0031981427
-
Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin 4 gene
-
Wei MX, Li F, Ono Y et al. Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin 4 gene. J. Neurovirol. 4(2), 237-241 (1998).
-
(1998)
J. Neurovirol.
, vol.4
, Issue.2
, pp. 237-241
-
-
Wei, M.X.1
Li, F.2
Ono, Y.3
|