Effects of low abdominal blood flow and dobutamine on blood flow distribution and on the hepatic arterial buffer response in anaesthetized pigs

Shock

Volumn 25, Issue 4, 2006, Pages 402-413

  Brander, Lukas ^a,b   Jakob, Stephan M ^a   Knuesel, Rafael ^a   Savolainen, Hannu ^a   Widmer, Matthias K ^a   Schmidli, Juerg ^a   Takala, Jukka ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Hepatic arterial buffer response; Regional blood flow; Splanchnic circulation

Indexed keywords

DOBUTAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA FLOW; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ECHOGRAPHY; FEMALE; HEART OUTPUT; HEPATIC ARTERY; KIDNEY BLOOD FLOW; LASER DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; NONHUMAN; PORTAL VEIN OBSTRUCTION; SPLANCHNIC BLOOD FLOW; SWINE;

ABDOMEN; ANIMALS; CARDIOTONIC AGENTS; DOBUTAMINE; FEMALE; HEPATIC ARTERY; MALE; REGIONAL BLOOD FLOW; SWINE;

EID: 33646773632     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000217813.50104.5d     Document Type: Article

References (39)

1. Kirton OC, Windsor J, Wedderburn R, Hudson-Civetta J, Shatz DV, Mataragas NR, Civetta JM: Failure of splanchnic resuscitation in the acutely injured trauma patient correlates with multiple organ system failure and length of stay in the ICU. Chest 113:1064-1069, 1998.
2. Schlichtig R, Kramer DJ, Pinsky MR: Flow redistribution during progressive hemorrhage is a determinant of critical O2 delivery. J Appl Physiol 70:169-178, 1991.
3. Creteur J, De Backer D, Sun Q, Vincent JL: The hepatosplanchnic contribution to hyperlactatemia in endotoxic shock: effects of tissue ischemia. Shock 21:438-443, 2004.
4. Reilly PM, Wilkins KB, Fuh KC, Haglund U, Bulkley GB: The mesenteric hemodynamic response to circulatory shock: an overview. Shock 15:329-343, 2001.
5. Varela JE, Cohn SM, Diaz I, Giannotti GD, Proctor KG: Splanchnic perfusion during delayed, hypotensive, or aggressive fluid resuscitation from uncontrolled hemorrhage. Shock 20:476-480, 2003.
6. Jakob SM, Merasto-Minkkinen M, Tenhunen JJ, Heino A, Alhava E, Takala J: Prevention of systemic hyperlactatemia during splanchnic ischemia. Shock 14:123-127, 2000.
7. Jakob SM, Tenhunen JJ, Laitinen S, Heino A, Alhava E, Takala J: Effects of systemic arterial hypoperfusion on splanchnic hemodynamics and hepatic arterial buffer response in pigs. Am J Physiol Gastrointest Liver Physiol 280:G819-G827, 2001.
8. Bailey RW, Bulkley GB, Hamilton SR, Morris JB, Haglund UH, Meilahn JE: The fundamental hemodynamic mechanism underlying gastric "stress ulceration" in cardiogenic shock. Ann Surg 205:597-612, 1987.
9. Jakob SM, Tenhunen JJ, Heino A, Pradl R, Alhava E, Takala J: Splanchnic vasoregulation during mesenteric ischemia and reperfusion in pigs. Shock 18:142-147, 2002.
10. De Backer D, Creteur J, Noordally O, Smail N, Gulbis B, Vincent JL: Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients? Am J Respir Crit Care Med 157:1219-1225, 1998.
11. Hayes MA, Timmins AC, Yau EHS, Palazzo M, Hinds CJ, Watson D: Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med 330:1717-1722, 1994.
12. Ruokonen E, Takala J, Uusaro A: Effect of vasoactive treatment on the relationship between mixed venous and regional oxygen saturation. Crit Care Med 19:1365-1369, 1991.
13. Uusaro A, Ruokonen E, Takala J: Splanchnic oxygen transport after cardiac surgery: evidence for inadequate tissue perfusion after stabilization of hemodynamics. Intensive Care Med 22:26-33, 1996.
14. Creteur J, De Backer D, Vincent JL: A dobutamine test can disclose hepatosplanchnic hypoperfusion in septic patients. Am J Respir Crit Care Med 160:839-845, 1999.
15. Gutierrez G, Clark C, Brown SD, Price K, Ortiz L, Nelson C: Effect of dobutamine on oxygen consumption and gastric-mucosal pH in septic patients. Am J Respir Crit Care Med 150:324-329, 1994.
16. Joly LM, Monchi M, Cariou A, Chiche JD, Bellenfant F, Brunet F, Dhainaut JF: Effects of dobutamine on gastric mucosal perfusion and hepatic metabolism in patients with septic shock. Am J Respir Crit Care Med 160: 1983-1986, 1999.
17. Neviere R, Mathieu D, Chagnon JL, Lebleu N, Wattel F: The contrasting effects of dobutamine and dopamine on gastric mucosal perfusion in septic patients. Am J Respir Crit Care Med 154:1684-1688, 1996.
18. Agusti M, Elizalde JI, Adalia R, Martinez-Palli G, Garcia-Valdecasas JC, Pique JM, Taura P: The effects of vasoactive drugs on hepatic blood flow changes induced by CO2 laparascopy: an animal study. Anesth Analg 93:1121-1126, 2001.
19. Heino A, Hartikainen J, Merasto ME, Koski EM, Tenhunen J, Alhava E, Takala J: Effects of dobutamine on splanchnic tissue perfusion during partial superior mesenteric artery occlusion. Crit Care Med 28:3484-3490, 2000.
20. Tenhunen JJ, Kosunen H, Alhava E, Tuomisto L, Takala JA: Intestinal luminal microdialysis: a new approach to assess gut mucosal ischemia. Anesthesiology 91:1807-1815, 1999.
21. Smits GJ, Roman RJ, Lombard JH: Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow. J Appl Physiol 61:666-672, 1986.
22. Hiltebrand LB, Krejci V, tenHoevel ME, Banic A, Sigurdsson GH: Redistribution of microcirculatory blood flow within the intestinal wall during sepsis and general anesthesia. Anesthesiology 98:658-669, 2003.
23. 2 gradients during isolated abdominal aortic blood flow reduction. Intensive Care Med 29:2255-2265, 2003.
24. Bracht H, Takala J, Tenhunen JJ, Brander L, Knuesel R, Merasto-Minkkinen M, Jakob SM: Hepatosplanchnic blood flow control and oxygen extraction are modified by the underlying mechanism of impaired perfusion. Crit Care Med 33:645-653, 2005.
25. Marshall JC, Christou NV, Meakins JL: The gastrointestinal tract. The "undrained abscess" of multiple organ failure. Ann Surg 218:111-119, 1993.
26. Moore EE, Moore FA, Franciose RJ, Kim FJ, Biffl WL, Banerjee A: The postischemic gut serves as a priming bed for circulating neutrophils that provoke multiple organ failure. J Trauma 37:881-887, 1994.
27. Ayuse T, Brienza N, O'Donnell CP, Robotham JL: Pressure-flow analysis of portal vein and hepatic artery interactions in porcine liver. Am J Physiol 267:H1233-H1242, 1994.
28. Lautt WW, McQuaker JE: Maintenance of hepatic arterial blood flow during hemorrhage is mediated by adenosine. Can J Physiol Pharmacol 67: 1023-1028, 1989.
29. Rasmussen A, Skak C, Kristensen M, Ott P, Kirkegaard P, Secher NH: Preserved arterial flow secures hepatic oxygenation during haemorrhage in the pig. J Physiol 516:539-548, 1999.
30. Rendig SV, Chahal PS, Longhurst JC: Cardiovascular reflex responses to ischemia during occlusion of celiac and/or superior mesenteric arteries. Am J Physiol 272:H791-H796, 1997.
31. Biro GP, Douglas JR, Keon WJ, Taichman GC: Changes in regional blood-flow distribution induced by infusions of dopexamine hydrochloride or dobutamine in anesthetized dogs. Am J Cardiol 62:C30-C36, 1988.
32. Parviainen I, Ruokonen E, Takala J: Dobutamine-induced dissociation between changes in splanchnic blood flow and gastric intramucosal pH after cardiac surgery. Br J Anaesth 74:277-282, 1995.
33. Ruokonen E, Takala J, Kari A: Regional blood-flow and oxygen-transport in patients with the low cardiac-output syndrome after cardiac-surgery. Crit Care Med 21:1304-1311, 1993.
34. Schneider AJ, Groeneveld ABJ, Teule GJJ, Wesdorp RIC, Thijs LG: Total-body blood-volume redistribution in porcine escherichia-coli septic shock - effect of volume loading, dobutamine, and norepinephrine. Circ Shock 35:215-222, 1991.
35. Ujita T, Nonami T, Kurokawa T, Kobayashi H, Takagi H: Hepatic hemodynamics and oxygen-metabolism during hepatic-artery occlusion and reperfusion - effects of dobutamine and inhalation of 100-percent oxygen. Eur Surg Res 26:149-155, 1994.
36. Priebe HJ, Noldge GFE, Armbruster K, Geiger K: Differential-effects of dobutamine, dopamine, and noradrenaline on splanchnic hemodynamics and oxygenation in the pig. Acta Anaesthesiol Scand 39:1088-1096, 1995.
37. Ferrara JJ, Dyess DL, Peeples GL, Christenberry DP, Roberts WS, Tacchi EJ, Swafford AN, Ardell JL, Powell RW: Effects of dopamine and dobutamine on regional blood-flow distribution in the neonatal piglet. Ann Surg 221: 531-542, 1995.
38. Guerin JP, Levraut J, Samat-Long C, Leverve X, Grimaud D, Ichai C: Effects of dopamine and norepinephrine on systemic and hepatosplanchnic hemodynamics, oxygen exchange, and energy balance in vasoplegic septic patients. Shock 23:18-24, 2005.
39. Lautt WW: The 1995 Ciba-Geigy Award Lecture. Intrinsic regulation of hepatic blood flow. Can J Physiol Pharmacol 74:223-233, 1996.